Modern Biopharmaceuticals Design Development And Optimization 4 2005
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Modern Biopharmaceuticals Design Development And Optimization 4 2005
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Author : Jörg Knäblein
language : en
Publisher:
Release Date : 2005
Modern Biopharmaceuticals Design Development And Optimization 4 2005 written by Jörg Knäblein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Modern Biopharmaceuticals Design Development And Optimization 3 2005
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Author : Jörg Knäblein
language : en
Publisher:
Release Date : 2005
Modern Biopharmaceuticals Design Development And Optimization 3 2005 written by Jörg Knäblein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Modern Biopharmaceuticals 4 Volume Set
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Author : Jörg Knäblein
language : en
Publisher: John Wiley & Sons
Release Date : 2005-10-28
Modern Biopharmaceuticals 4 Volume Set written by Jörg Knäblein and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-28 with Science categories.
The biopharmaceutical market has come along way since 1982 when the first biopharmaceutical product, recombinant human insulin, was launched. Over 120 such products are currently being marketed around the world including nine blockbuster drugs. The global market for biopharmaceuticals, which is currently valued at US$41 billion, has been growing at an impressive compound annual growth rate of 21% over the previous five years. With over one third of all pipe-line products in active development are biopharmaceuticals, this segment is set to continue outperforming the total pharmaceutical market and could easily reach US$100 billion by the end of this decade.
Modern Biopharmaceuticals
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Author : Jörg Knäblein
language : en
Publisher:
Release Date : 2005
Modern Biopharmaceuticals written by Jörg Knäblein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Modern Biopharmaceuticals
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Author : Jörg Knäblein
language : en
Publisher: John Wiley & Sons
Release Date : 2013-05-07
Modern Biopharmaceuticals written by Jörg Knäblein and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-07 with Science categories.
This collection of high-profile contributions provides a unique insight into the development of novel, successful biopharmaceuticals. Outstanding authors, including Nobel laureate Robert Huber as well as prominent company researchers and CEOs, present valuable insider knowledge, limiting their scope to those procedures and developments with proven potential for the biotechnology industry. They cover all relevant aspects, from the establishment of biotechnology parks, the development of successful compounds and the implementation of efficient manufacturing processes, right up to the establishment of advanced delivery routes.
Aqueous Two Phase Systems For Bioprocess Development For The Recovery Of Biological Products
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Author : Marco Rito-Palomares
language : en
Publisher: Springer
Release Date : 2017-07-18
Aqueous Two Phase Systems For Bioprocess Development For The Recovery Of Biological Products written by Marco Rito-Palomares and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-18 with Technology & Engineering categories.
This comprehensive and unique text presents a full overview of downstream processing useful for those new to the concept as well as professionals with experience in the area. The history and theoretical principles of Aqueous Two-Phase Systems (ATPS) are covered in depth. Information on ATPS characterization and application is included, and ATPS equilibria and system parameters that have significant effect on partition behavior are studied. Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products addresses specific applications of ATPS for the recovery and partial purification of high molecular weight compounds such as proteins, nucleic acids and polysaccharides, particulate bioproducts such as cells and organelles and low molecular weight compounds. Non-conventional strategies involving ATPS such as affinity systems, continuous liquid-liquid fractionation stages and the recovery from plant extracts are presented. Economic analysis of the application of ATPS in comparison to other fractionation techniques, particularly liquid chromatography, is considered, as are opportunity and current trends in the ATPS research area. Each chapter utilizes the contributors' experimental expertise in traditional and non-conventional ATPS strategies, as well as analysis of areas of opportunity and perspectives on the development and future applications of ATPS in both the lab and larger scale operations. The result is a thorough and singular overview of ATPS which has not been matched by any other text on the market.
Pharmacokinetics And Pharmacodynamics Of Biotech Drugs
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Author : Bernd Meibohm
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-13
Pharmacokinetics And Pharmacodynamics Of Biotech Drugs written by Bernd Meibohm and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Science categories.
This first ever coverage of the pharmacokinetic and pharmacodynamic characteristics of biopharmaceuticals meets the need for a comprehensive book in this field. It spans all topics from lead identification right up to final-stage clinical trials. Following an introduction to the role of PK and PD in the development of biotech drugs, the book goes on to cover the basics, including the pharmacokinetics of peptides, monoclonal antibodies, antisense oligonucleotides, as well as viral and non-viral gene delivery vectors. The second section discusses such challenges and opportunities as pulmonary delivery of proteins and peptides, and the delivery of oligonucleotides. The final section considers the integration of PK and PD concepts into the biotech drug development plan, taking as case studies the preclinical and clinical drug development of tasidotin, as well as the examples of cetuximab and pegfilgrastim. The result is vital reading for all pharmaceutical researchers.
Mass Spectrometry In Biopharmaceutical Analysis
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Author : Igor A. Kaltashov
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2021-11-22
Mass Spectrometry In Biopharmaceutical Analysis written by Igor A. Kaltashov and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-22 with Science categories.
Biopharmaceuticals are a unique class of compounds due to their extreme structural complexity. The current text puts together a variety of the state‐of‐the art approaches that use mass spectrometry to evaluate various aspects of biopharmaceutical products ranging from monitoring stress‐related structural changes to their quantitation in pharmacokinetic studies.
Production Of Recombinant Proteins
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Author : Gerd Gellissen
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06
Production Of Recombinant Proteins written by Gerd Gellissen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.
While the choices of microbial and eukaryotic expression systems for production of recombinant proteins are many, most researchers in academic and industrial settings do not have ready access to pertinent biological and technical information since it is normally scattered throughout the scientific literature. This book closes the gap by providing information on the general biology of the host organism, a description of the expression platform, a methodological section -- with strains, genetic elements, vectors and special methods, where applicable -- as well as examples of proteins produced with the respective platform. The systems thus described are well balanced by the inclusion of three prokaryotes (two Gram-negatives and one Gram-positive), four yeasts, two filamentous fungi and two higher eukaryotic cell systems -- mammalian and plant cells. Throughout, the book provides valuable practical and theoretical information on the criteria and schemes for selecting the appropriate expression platform, the possibility and practicality of a universal expression vector, and on comparative industrial-scale fermentation, with the production of a recombinant Hepatitis B vaccine chosen as an industrial example. With a foreword by Herbert P. Schweizer, Colorado State University, USA: "As a whole, this book is a valuable and overdue resource for a varied audience. It is a practical guide for academic and industrial researchers who are confronted with the design of the most suitable expression platform for their favorite protein for technical or pharmaceutical purposes. In addition, the book is also a valuable study resource for professors and students in the fields of applied biology and biotechnology."
Proteins
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Author : Robert A. Meyers
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-25
Proteins written by Robert A. Meyers and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-25 with Science categories.
With three Nobel Laureates contributing to this invaluable collection of high-quality articles, carefully selected from the highly praised R.A. Meyer's Encyclopedia, these two volumes cover a wide range of topics in protein research. Clearly divided into sections on structure, modeling, expression, analysis and others, the chapters are designed to aid readers of all levels of expertise: Each chapter includes a glossary of the most important keywords, a concise summary of the article concerned and comprehensive references for further reading. Similarly, the uniform structure of the articles makes them very easy to use, resulting in a ready reference for molecular and cell biologists, biochemists, biophysicists, and biotechnologists, as well as those working in the pharmaceutical and biotechnological industries.