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Modes Of Action Of Gnrh And Gnrh Analogs


Modes Of Action Of Gnrh And Gnrh Analogs
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Modes Of Action Of Gnrh And Gnrh Analogs


Modes Of Action Of Gnrh And Gnrh Analogs
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Author : William F. Jr. Crowley
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Modes Of Action Of Gnrh And Gnrh Analogs written by William F. Jr. Crowley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Since the awarding of the Nobel Prize to Drs. Guillemin and Schally iJ) 1971 for isolation and chemical characterization of gonadotropin releasing hormone, we have experienced a remarkable period of growth of interest in this hormone. The last 20 years have been characterized by a swift translation of basic science discovery into clinical utility. Approval of GnRH and its analogs for treatment of prostate cancer, endometriosis, of ovulation indicate the range and precocious puberty and for induction of these agents. of usefulness In order to bring together the leaders in the basic and clinical science of GnRH, a conference was organized on "Modes of Action of GnRH and GnRH Analogs" and held in Scottsdale, Arizona, February 26 to March 2, 1991. The presentations, given as chapters in this volume, show both the advances in the body of information in this discipline and the efforts underway to reduce basic science to clinical practice. The audience was a combination of representatives from universities, government, industry, and physicians in practice. The lively discussions and insightful questions indicated the interest in the topics discussed and frequently served to catalyze planned interactions of the meeting participants. The organizers are grateful to the speakers and poster presenters for their contributions and for the timely preparations of the manuscripts included in the present volume. We are also thankful to the staff of Serono Symposia, USA, for the organizational skills and support that allowed the meeting organizers to focus on the science and medicine presented.



Hepatotoxicity


Hepatotoxicity
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Author : Hyman J. Zimmerman
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1999

Hepatotoxicity written by Hyman J. Zimmerman and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.


Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.



Pubertal Suppression In Transgender Youth


Pubertal Suppression In Transgender Youth
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Author : Courtney Finlayson
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-08-03

Pubertal Suppression In Transgender Youth written by Courtney Finlayson and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-03 with Medical categories.


Offering current guidelines on the relatively new practice of puberty suppression for gender-dysphoric adolescents, Pubertal Suppression in Transgender Youth provides a succinct, easy-to-digest overview of this timely topic. This concise, clinically-focused resource by Dr. Courtney Finlayson covers all relevant topics, from a brief history of medical care of transgender youth to emerging developments in the field. - Covers the use of gonadotropin-releasing hormone agonist (GnRHa) therapy in transgender youth, including models of care and current treatment guidelines, fertility issues, ethical considerations and the consent process, and more. - Discusses psychosocial, medical, and surgical side effects of treatment. - Consolidates today's available information on this timely topic into one convenient resource.



Clinical Gynaecology


Clinical Gynaecology
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Author : T. F. Kruger
language : en
Publisher: Juta and Company Ltd
Release Date : 2007

Clinical Gynaecology written by T. F. Kruger and has been published by Juta and Company Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.


Presenting the basis for gynecological studies in South Africa, this comprehensive examination, compiled by 32 leaders in the field, describes the history and basics of gynecology—including genetics, embryology, anatomy, physiology, and cytology bioethics. Incorporating information on the latest diagnostic and therapeutic procedures, HIV/AIDS, abuse and violence against women, and access to gynecological data via electronic media, this third edition includes eight new chapters, a DVD that shows live techniques and procedures, and a quick-reference guide summarizing the salient points of each chapter. An invaluable resource for undergraduates, postgraduate students, and practicing physicians, the topics covered in this authoritative handbook apply not only to sub-Saharan Africa but to any developing community.



Integration Of Pharmaceutical Discovery And Development


Integration Of Pharmaceutical Discovery And Development
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Author : Ronald T. Borchardt
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-01-19

Integration Of Pharmaceutical Discovery And Development written by Ronald T. Borchardt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-19 with Science categories.


In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift occurred in which drug design and development activities became more highly integrated. This new str- egy required medicinal chemists to design drug candidates with structural f- tures that optimized pharmacological (e. g. , high affinity and specificity for the target receptor), pharmaceutical (e. g. , solubility and chemical stability), bioph- maceutical (e. g. , cell membrane permeability), and metabolic/pharmacokinetic (e. g. , metabolic stability, clearance, and protein binding) properties. Successful implementation of this strategy requires a multidisciplinary team effort, incl- ing scientists from drug design (e. g. , medicinal chemists, cell biologists, en- mologists, pharmacologists) and drug development (e. g. , analytical chemists, pharmaceutical scientists, physiologists, and molecular biologists representing the disciplines of pharmaceutics, biopharmaceutics, and pharmacokinetics/drug metabolism). With this new, highly integrated approach to drug design now widely utilized by the pharmaceutical industry, the editors of this book have provided the sci- tific community with case histories to illustrate the nature of the interdisciplinary interactions necessary to successfully implement this new approach to drug d- covery. In the first chapter, Ralph Hirschmann provides a historical perspective of why this paradigm shift in drug discovery has occurred.



Principles And Practice Of Controlled Ovarian Stimulation In Art


Principles And Practice Of Controlled Ovarian Stimulation In Art
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Author : Surveen Ghumman
language : en
Publisher: Springer
Release Date : 2015-09-22

Principles And Practice Of Controlled Ovarian Stimulation In Art written by Surveen Ghumman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-22 with Health & Fitness categories.


This book is on ovulation induction and controlled ovarian stimulation which is an integral part of most infertility therapies like intrauterine insemination and in vitro fertilization. It would deal with causes of anovulation and indications for ovarian stimulation. This book deals with basics as well as current and advanced practices. It provides a step by step protocol for ovarian stimulation. It gives a clear understanding of the science of reproductive endocrinology behind these stimulation protocols and roadmaps the latest therapies, defining their current relevance to treatment. Besides the practical guidance it also covers latest research work done in this field. In this day of information overload it is an attempt to integrate relevant information in a manner which can be applied in infertility practice in evidence based manner, making it rational, logical and rewarding for the reader.



Modern Approaches To Endometriosis


Modern Approaches To Endometriosis
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Author : Eric J. Thomas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Modern Approaches To Endometriosis written by Eric J. Thomas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Endometriosis provides a unique clinical and scientific challenge. It is being diagnosed with increasing frequency and yet we are unsure of the significance of this in many patients. Its appearance varies from a tiny focus of disease to a potently destructive phenomenon. Weare still unsure of the relative value of medical or surgical treatment. The pathogenesis and control of the cellular function of the disease proVide many scientific problems. The presence of a comparative normal epithelium, namely endometrium, provides a unique research opportunity. It is probable that only through basic science research will we be able to solve the clinical dilemmas that endometriosis presents. We felt that it was important to create a book that explored the important scientific and clinical problems. We therefore invited acknowledged experts from both Europe and the United States of America to review their fields. The purpose of these reviews is not only to provide a resource for clinicians and scientists but also to stimulate thought and new ideas for research and treatment. To fulfil that aim we have asked that the authors be more speculative than normal for a volume such as this. We thank them for responding to their task so well and hope that you will feel as stimulated by their efforts as we have been.



A Case Based Guide To Clinical Endocrinology


A Case Based Guide To Clinical Endocrinology
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Author : Terry F. Davies
language : en
Publisher: Springer
Release Date : 2015-10-22

A Case Based Guide To Clinical Endocrinology written by Terry F. Davies and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-22 with Medical categories.


In A Case-Based Guide to Clinical Endocrinology, Second Edition, a renowned group of distinguished clinicians once again provides stimulating instruction and insights into a wide variety of endocrine topics, teaching readers modern management of the conditions described and offering targeted entry into the literature. Importantly, many of the important elements in the current curriculum for clinical endocrine training as recommended by the Association of Program Directors in Clinical Endocrinology, Diabetes and Metabolism are covered in this text. Thoroughly updated, this new edition not only covers new treatment approaches but also emphasizes the latest investigative advances in both imaging and molecular diagnostics. To reinforce learning and retention of knowledge, a question-based approach is used in many of the case studies. Students, residents, fellows, and practitioners will find this reference to be an efficient way to review their understanding and increase their skills and abilities in patient investigation and management. An invaluable contribution to the field, A Case-Based Guide to Clinical Endocrinology, Second Edition, offers the same comprehensive volume of thought-provoking case-studies that made the first edition of significant importance to all clinicians who treat patients with endocrine disorders.



National Library Of Medicine Current Catalog


National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1993

National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.




Lh Rh And Its Analogues


Lh Rh And Its Analogues
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Author : Manfred Schmidt-Gollwitzer
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-11-18

Lh Rh And Its Analogues written by Manfred Schmidt-Gollwitzer and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-18 with Technology & Engineering categories.


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