Molecular And Cellular Methods In Developmental Toxicology

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Molecular And Cellular Methods In Developmental Toxicology

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Author : George P. Daston
language : en
Publisher: CRC Press
Release Date : 2019-04-30

Molecular And Cellular Methods In Developmental Toxicology written by George P. Daston and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-30 with Medical categories.

This new manual provides a convenient source of experimental procedures, including the most modern and frequently used molecular and cellular techniques. Experimental protocols have been carefully selected by developmental toxicologists for developmental toxicologists. The most important new trends, such as evaluation of the safety of therapeutic antisense oligonucleotides, studies of the role of cell death in abnormal development, and the identification of sparingly expressed developmental control genes are featured. This is the perfect manual for scientists trained in classical developmental toxicology who want to add molecular and cellular methods to their research.

Molecular And Cellular Methods In Developmental Toxicology

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Author : George P. Daston
language : en
Publisher:
Release Date : 1997

Molecular And Cellular Methods In Developmental Toxicology written by George P. Daston and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with MEDICAL categories.

Molecular And Cellular Methods In Developmental Toxicology

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Author : George P. Daston
language : en
Publisher: CRC-Press
Release Date : 1996-09-26

Molecular And Cellular Methods In Developmental Toxicology written by George P. Daston and has been published by CRC-Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-09-26 with Science categories.

This new manual provides a convenient source of experimental procedures, including the most modern and frequently used molecular and cellular techniques. Experimental protocols have been carefully selected by developmental toxicologists for developmental toxicologists. The most important new trends, such as evaluation of the safety of therapeutic antisense oligonucleotides, studies of the role of cell death in abnormal development, and the identification of sparingly expressed developmental control genes are featured. This is the perfect manual for scientists trained in classical developmental toxicology who want to add molecular and cellular methods to their research.

Developmental Biology Protocols

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Author : Rocky S. Tuan
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05

Developmental Biology Protocols written by Rocky S. Tuan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Science categories.

Developmental biology is one of the most exciting and fast-growing fields today. In part, this is so because the subject matter deals with the innately fascinating biological events—changes in form, structure, and function of the org- ism. The other reason for much of the excitement in developmental biology is that the field has truly become the unifying melting pot of biology, and provides a framework that integrates anatomy, physiology, genetics, biochemistry, and cellular and mole- lar biology, as well as evolutionary biology. No longer is the study of embryonic development merely “embryology.” In fact, development biology has produced - portant paradigms for both basic and clinical biomedical sciences alike. Although modern developmental biology has its roots in “experimental emb- ology” and the even more classical “chemical embryology,” the recent explosive and remarkable advances in developmental biology are critically linked to the advent of the “cellular and molecular biology revolution.” The impressive arsenal of expe- mental and analytical tools derived from cell and molecular biology, which promise to continue to expand, together with the exponentially developing sophistication in fu- tional imaging and information technologies, guarantee that the study of the devel- ing embryo will contribute one of the most captivating areas of biological research in the next millennium.

In Vitro Methods In Developmental Toxicology

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Author : Gary L. Kimmel
language : en
Publisher: CRC Press
Release Date : 2019-06-04

In Vitro Methods In Developmental Toxicology written by Gary L. Kimmel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.

First Published in 1990, this text brings together the work of several investigators who used in vitro techniques to probe the nature of embryonic cell response to a diverse group of chemical agents. It focuses on the approaches, limitations, usefulness and applicability of defining mechanisms underlying altered development. This work includes discussions on pharmacodynamic principles and placental transfer mechanisms. It also examines the potential for in vitro systems to serve as an adjunct to the risk assessment process. Ideal for both the layman and the expert in this area, this volume provides a general understanding of the types of approaches that can be used and specific approaches in investigating altered development.

Tobacco Specific N Nitrosamines Recent Advances

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Author : Roger O. McClellan
language : en
Publisher: CRC Press
Release Date : 1996-05-10

Tobacco Specific N Nitrosamines Recent Advances written by Roger O. McClellan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-05-10 with Medical categories.

This remarkable book provides updates on various aspects of tobacco - its chemical and biological nature, and its physiological effects.

Information Resources In Toxicology

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Author : P.J. Bert Hakkinen
language : en
Publisher: Elsevier
Release Date : 2000-01-10

Information Resources In Toxicology written by P.J. Bert Hakkinen and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-10 with Medical categories.

Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. - Serves as an all-in-one resource for toxicology information - New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports - Updated to include the latest internet and electronic sources, e-mail addresses, etc. - Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects

Molecular And Cellular Toxicology

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Author : Lesley Stanley
language : en
Publisher: John Wiley & Sons
Release Date : 2014-06-03

Molecular And Cellular Toxicology written by Lesley Stanley and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-03 with Medical categories.

Toxicology is the study of the adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Toxicologists are trained to investigate, interpret, and communicate the nature of those effects. Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which takes advantage of the opportunities offered by modern developments in the life sciences, including new in vitro and in silico approaches, alternative whole organism (non-mammalian) models and the exploitation of ‘omics methods, high throughput screening (HTS) techniques and molecular imaging technologies. This concise, accessible introduction to the field includes the very latest concepts and methodologies. It provides MSc, PhD and final year undergraduate students in pharmacy, biomedical and life sciences, as well as individuals starting out in the cosmetics, consumer products, pharmaceutical and testing industries, with everything they need to know to get to grips with the fast moving field of toxicology and the current approaches used in the risk assessment of drugs and chemicals.

Developmental And Reproductive Toxicology

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Author : Ronald D. Hood
language : en
Publisher: CRC Press
Release Date : 2005-08-30

Developmental And Reproductive Toxicology written by Ronald D. Hood and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-30 with Medical categories.

Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e

Atlas Of Chick Development

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Author : Ruth Bellairs
language : en
Publisher: Academic Press
Release Date : 2014-05-19

Atlas Of Chick Development written by Ruth Bellairs and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-19 with Science categories.

The Atlas of Chick Development, Third Edition, a classic work covering all major event of chick development, is extensively updated with new and more detailed photographs, enlargements showing regions of special-interest and complexity, and new illustrations. The revised text and expanded illustrative material describe the intricate changes that take place during development, together with accounts of recent experimental and molecular research that has transformed our understanding of morphogenesis. These wide-ranging updates make this book an essential resource for developmental biologists, geneticists, molecular biologists, poultry scientists, biochemists, immunologists, and other life scientists who use the chick embryo as their research model. Individuals joining this burgeoning area, ignited by the increased insight into events surrounding organ and tissue differentiation, will find this a valuable tool to help grow a basic knowledge of morphogenesis. - Remains the established standard—the only book providing a comprehensive description of chick development from fertilization to hatching - Contains more than 750 photographs and illustrations, including 410 labelled histological sections and 85 new high-quality plates, showing the major anatomical events from the earliest stages to 13 days of incubation - Includes more than 200 labelled and detailed scanning electron micrographs, showing various tissues in great detail - Leads the reader to important reviews on aspects of this rapidly moving field, along with extensive and updated references