Molecular Basis Of Pulmonary Disease
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Molecular Basis Of Pulmonary Disease
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Author : Francis X. McCormack
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10
Molecular Basis Of Pulmonary Disease written by Francis X. McCormack and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Medical categories.
The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Lung Disease: Insights from Rare Disorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy to read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture’s syndromes to Sarcoidosis and alpha one titrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis of Lung Disease: Insights from Rare Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.
The Lung
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Author : Jerome S. Brody
language : en
Publisher: Saunders
Release Date : 1998
The Lung written by Jerome S. Brody and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
This user-friendly reference provides a basic understanding of the molecular biology underlying pulmonary diseases. Presents the background information necessary to understand the impact that molecular biology has on pulmonary medicine. Chapters begin with a list of basic concepts and a summary of the state-of-the-art information for each disease, starting with a clinical-molecular point of view and concluding with an annotated bibliography. Features excellent color illustrations and a thorough appendix!
Lung Epithelial Biology In The Pathogenesis Of Pulmonary Disease
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Author : Venkataramana K Sidhaye
language : en
Publisher: Academic Press
Release Date : 2017-03-09
Lung Epithelial Biology In The Pathogenesis Of Pulmonary Disease written by Venkataramana K Sidhaye and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-09 with Medical categories.
Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences
Treatment Of Cystic Fibrosis And Other Rare Lung Diseases
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Author : Arata Azuma
language : en
Publisher: Springer
Release Date : 2017-01-28
Treatment Of Cystic Fibrosis And Other Rare Lung Diseases written by Arata Azuma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-28 with Medical categories.
This volume describes the pathogenesis and pathophysiology of several pulmonary diseases as well as their treatment. It also discusses the underlying genetic and molecular biological basis, which opens the way for new treatments for these conditions. It focuses on the treatment of cystic fibrosis including CFTR (cystic fibrosis transmembrane-conductance regulator) modulator therapies, drug therapies that augment airway surface liquid as well as anti-inflammatory and anti-infective therapies. Further topics include long-term, low-dose macrolide therapy for diffuse panbronchiolitis; novel agents for previously untreatable idiopathic pulmonary fibrosis; possible new treatments for pulmonary alveolar proteinosis (PAP); and multiple novel therapeutic targets for treating lymphangiomyomatosis. Research into these conditions has led to major advances in our understanding of the underlying genetic and molecular basis of this disease, and to dramatic improvements in survival and quality of life for affected individuals.
Genetics For Pulmonologists
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Author : Jordan Prutkin
language : en
Publisher: Remedica
Release Date : 2002
Genetics For Pulmonologists written by Jordan Prutkin and has been published by Remedica this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Lung Diseases categories.
Our understanding of the relationship between genetics and pulmonary disorders is still evolving. In 1989 cloning of the gene that, when mutated, causes cystic fibrosis marked a great advance in the study of genetic diseases. Yet, over a decade later, understanding of how this genetic defect leads to colonization by bacteria and inflammation in the lung remains elusive.
Essential Concepts In Molecular Pathology
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Author : William B. Coleman
language : en
Publisher: Academic Press
Release Date : 2019-11-23
Essential Concepts In Molecular Pathology written by William B. Coleman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-23 with Medical categories.
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Molecular Biology Of The Lung
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Author : Robert Stockley
language : en
Publisher: Birkhäuser
Release Date : 1998-12-01
Molecular Biology Of The Lung written by Robert Stockley and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-12-01 with Medical categories.
The techniques and knowledge in molecular biology are advancing rapidly. The basic mechanisms involved in the pathogenesis of various lung conditions including asthma, COPD and lung cancer are being clarified by the application of this powerful technology. Genetic causes of single gene disorders such as cystic fibrosis and alpha-1 antitrypsin deficiency have now been well delineated. This progress leads to an understanding of the pathogenic process that result in disease. The purpose of Volumes I and II of "Molecular Biology of the Lung" is to provide an update on the use of this powerful technology. As such, the books provide an insight into the techniques for the non-specialist. Scientists embarking upon studies in chronic lung disease will find a review of the current status of research. At the same time, the books are useful to clinicians, both specialist and academic, and to scientists already involved in the basic aspects of the pathogenesis of lung disease. Both volumes deal with basic mechanisms of cell biology, receptors and cell activation and provides an insight as to how the technology influences our concepts of pathogenesis and vice versa.
Clinical Relevance Of Genetic Factors In Pulmonary Diseases
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Author : Takeshi Kaneko
language : en
Publisher: Springer
Release Date : 2018-07-12
Clinical Relevance Of Genetic Factors In Pulmonary Diseases written by Takeshi Kaneko and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-12 with Medical categories.
This book describes the underlying genetic basis of common pulmonary diseases and discusses their pathogenesis and pathophysiology. These insights provide the basis for understanding different subtypes and phonotypes, and will promote better treatment strategies and individualized medicine. The book provides new and valuable information for the development of the areas of study, as well as practical guidelines for clinicians engaged in treating pulmonary diseases. This volume of the Respiratory Disease Series – Diagnostic Tools and Disease Managements will broaden the understanding of beginning and experienced researchers and clinicians who treat pulmonary diseases. Moreover, residents and clinicians engaged in medical oncology will find it a valuable guide to support them in their day-to-day work.
Molecular Biology Of The Lung
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Author : Robert A. Stockley
language : en
Publisher: Springer Science & Business Media
Release Date : 1998
Molecular Biology Of The Lung written by Robert A. Stockley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
The purpose of this two-volume work is to provide an update on the use of this powerful technology. As such, the books provide an insight in to the techniques for the non-specialist. Scientists embarking upon st udies in chronic lung disease will find a review of the current status of research. At the same time, the books are useful to clinicians, bo th specialist and academic, and to scientists already involved in the basic aspects of the pathogenesis of lung disease. Both volumes deal w ith basic mechanisms of cell biology, receptors and cellactivation and provide an insight as to how the technology influences our concepts o f pathogenesis and viceversa.
Smoking And Lung Inflammation
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Author : Thomas J. Rogers
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-12
Smoking And Lung Inflammation written by Thomas J. Rogers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-12 with Medical categories.
Smoking and Lung Inflammation is the first book directly related to chronic lung inflammation of its kind in several respects. First, the it focuses on both basic and clinical research on COPD, and the inflammatory mechanisms that function in these diseases. Second, it is unique with respect to scope of the discussion of the unusual characteristics of the immune response which occurs in these patients. Third, it includes knowledge being gained from translational research conducted through clinical trials at several Medical Schools in the United States. Not only is this research providing information about novel drugs and therapies, but it is also advancing our understanding of the genetics of these diseases. This work will illuminate the molecular basis for these diseases, and hopefully will permit us to individualize the therapies for these diseases.