Treatment Of Cystic Fibrosis And Other Rare Lung Diseases
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Treatment Of Cystic Fibrosis And Other Rare Lung Diseases
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Author : Arata Azuma
language : en
Publisher: Springer
Release Date : 2017-01-28
Treatment Of Cystic Fibrosis And Other Rare Lung Diseases written by Arata Azuma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-28 with Medical categories.
This volume describes the pathogenesis and pathophysiology of several pulmonary diseases as well as their treatment. It also discusses the underlying genetic and molecular biological basis, which opens the way for new treatments for these conditions. It focuses on the treatment of cystic fibrosis including CFTR (cystic fibrosis transmembrane-conductance regulator) modulator therapies, drug therapies that augment airway surface liquid as well as anti-inflammatory and anti-infective therapies. Further topics include long-term, low-dose macrolide therapy for diffuse panbronchiolitis; novel agents for previously untreatable idiopathic pulmonary fibrosis; possible new treatments for pulmonary alveolar proteinosis (PAP); and multiple novel therapeutic targets for treating lymphangiomyomatosis. Research into these conditions has led to major advances in our understanding of the underlying genetic and molecular basis of this disease, and to dramatic improvements in survival and quality of life for affected individuals.
Orphan Lung Diseases
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Author : Vincent Cottin
language : en
Publisher: Springer
Release Date : 2015-01-10
Orphan Lung Diseases written by Vincent Cottin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-10 with Medical categories.
Orphan Lung Diseases: A Clinical Guide to Rare Lung Disease provides a comprehensive, clinically focused textbook on rare and so-called ‘orphan’ pulmonary diseases. The book is oriented towards the diagnostic approach, including manifestations suggesting the disease, diagnostic criteria, methods of diagnostic confirmation, and differential diagnosis, with an overview of management.
Molecular Basis Of Pulmonary Disease
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Author : Francis X. McCormack
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-10
Molecular Basis Of Pulmonary Disease written by Francis X. McCormack and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-10 with Medical categories.
The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Lung Disease: Insights from Rare Disorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy to read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture’s syndromes to Sarcoidosis and alpha one titrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis of Lung Disease: Insights from Rare Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.
Stem Cell Based Therapy For Lung Disease
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Author : Janette K. Burgess
language : en
Publisher: Springer Nature
Release Date : 2019-11-23
Stem Cell Based Therapy For Lung Disease written by Janette K. Burgess and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-23 with Science categories.
This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.
Difficult To Diagnose Rare Diffuse Lung Disease
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Author : Alexander V. Averyanov
language : en
Publisher: Academic Press
Release Date : 2019-08-24
Difficult To Diagnose Rare Diffuse Lung Disease written by Alexander V. Averyanov and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-24 with Science categories.
Difficult to Diagnose Rare Diffuse Lung Disease presents the theoretical basis and practical aspects of differential diagnoses of rare lung diseases with the use of new method of probe-based confocal laser endomicroscopy (alveoscopy) of the distal respiratory region. Each chapter describes signs and symptoms of the disease and its typical and atypical manifestations. The book contains full color illustrations, including high-resolution histological microphotographs, CT-scans and confocal laser endomicroscopy images. In combination, these elements make this book an invaluable reference and guide for pulmonary researchers, pulmonologists, radiologists, and pathologists who wish to broaden their spectrum of knowledge in rare lung diseases. Highlights the new method of probe-based confocal laser endomicroscopy (alveoscopy) of the distal respiratory region, opening new horizons in the minimally invasive diagnosis of lung diseases Discusses current treatment strategies in accordance with clinical guidelines, including data from the latest clinical trials Presented in tabular format to aid in the diagnostic process
Cystic Fibrosis
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Author : Prashant Mohite
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-06-09
Cystic Fibrosis written by Prashant Mohite and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-09 with Medical categories.
Cystic fibrosis, a genetic disorder in children and young adults, is a multisystemic disease that mainly affects the lungs. Advances and improvements in the diagnosis and management of this condition have led to increased overall and symptom-free survival in cystic fibrosis patients. This book examines recent advances in the field and presents an evidence-based approach to the management of cystic fibrosis.
Rare Lung Diseases
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Author : Sujith V. Cherian
language : en
Publisher: CRC Press
Release Date : 2023-03-13
Rare Lung Diseases written by Sujith V. Cherian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-13 with Medical categories.
This book aims to be a complete guide to diagnose, manage, and treat rare lung diseases encountered by practicing pulmonologists and trainees. It extensively covers the "more common" of the rare lung diseases, categorizing them based on developmental lung anomalies in adults, airway disorders, diffuse parenchymal lung diseases, neoplasms, rare vascular disorders, and other miscellaneous conditions. This comprehensive review facilitates the study and understanding of this complex and diverse set of disorders, focusing on differential diagnosis, evidence-based discussions of management algorithms, and thoughtful analysis of treatment options. Key Features * Reviews multiple rare lung diseases, including ones acquired congenitally to be expressed in old age * Enriched with case studies and illustrations to guide respiratory physicians and trainees to devise an effective treatment plan *Focuses on concerned investigations, with a section on the role of new procedures in management
Cystic Fibrosis In The Light Of New Research
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Author : Dennis Wat
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-08-24
Cystic Fibrosis In The Light Of New Research written by Dennis Wat and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-24 with Medical categories.
Cystic Fibrosis in the Light of New Research provides the latest research and clinical evidence that will be useful for clinicians, scientists and researchers to further their knowledge around this fascinating condition. The authors have brought along their expertise and wealth of knowledge to produce this book, including the basic science that underlies the disease, the burden of bacterial and viral infections, immunologic aspects of CF, a variety of clinical measurements to predict prognosis and novel therapies including gene therapy. This book will be invaluable and entertaining for anyone who is involved in the care of patients with cystic fibrosis.
Orphan Lung Diseases
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Author : J-F. Cordier
language : en
Publisher: European Respiratory Society
Release Date : 2011-12-01
Orphan Lung Diseases written by J-F. Cordier and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-01 with Medical categories.
This book has been replaced by "Rare Diseases of the Respiratory System", ISBN 978-1-84984-167-2 A respiratory physician is only likely to see a few orphan lung diseases each year or even during their career. However, it is essential that specialists are able identify, confirm and diagnosis orphan lung disease in a patient. This Monograph comprehensively covers the most common and/or complex orphan lung diseases. It should be seen as a solid companion to the respiratory specialist each time they need to consider a diagnosis of an orphan disease.
Diffuse Cystic Lung Diseases
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Author : Nishant Gupta
language : en
Publisher: Springer Nature
Release Date : 2021-01-28
Diffuse Cystic Lung Diseases written by Nishant Gupta and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-28 with Medical categories.
This book is a comprehensive reference on diffuse cystic lung diseases (DCLDs). DCLDs are a group of pathophysiologically heterogenous processes that are characterized by the presence of multiple spherical or irregularly shaped, thin-walled, air-filled spaces within the pulmonary parenchyma. In recent years, tremendous advancements have been made in these diseases leading to improved understanding of the underlying pathophysiology, and improved outcomes with targeted therapies. The authors, who are leading experts in the field, delineate DCLDs as a separate category distinct from other interstitial lung diseases, and have created this textbook specifically dedicated to this disease group. This book begins with a chapter introducing the definition and classification of DCLDs. Subsequent chapters address the pathogenic mechanisms underlying pulmonary cyst formation and provide a detailed overview of the radiological and pathological features of DCLDs. The common as well as uncommon causes of DCLDs are comprehensively reviewed in individual chapters, as are the varied clinical presentations and extrapulmonary manifestations, and approaches to management and treatment. The book culminates in a final chapter that presents a practical algorithmic approach to diagnosis that progresses from least invasive to most invasive approaches. This textbook provides a one-stop, comprehensive and integrated, clinical, radiologic, and pathologic overview of DCLDs that will be as useful to the practicing clinician as it is to the clinical investigator.