Molecular Evolution
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Fundamentals Of Molecular Evolution
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Author : Dan Graur
language : en
Publisher: Sinauer Associates Incorporated
Release Date : 2000-01
Fundamentals Of Molecular Evolution written by Dan Graur and has been published by Sinauer Associates Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01 with Medical categories.
Genes, genetic codes, and mutation. Dynamics of genes in populations. Evolutionary change in nucleotide sequences. Rates and patterns of nucleotide substitution. Molecular phylogenetics. Gene duplication, exon shuffling, and concerted evolution. Evolution by transposition. Genome evolution. Spatial and temporal frameworks of the evolutionary process. Basics of probability.
Molecular Evolution
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Author : Roderick D.M. Page
language : en
Publisher: John Wiley & Sons
Release Date : 2009-07-14
Molecular Evolution written by Roderick D.M. Page and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-14 with Science categories.
The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.
The Causes Of Molecular Evolution
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Author : John H. Gillespie
language : en
Publisher: Oxford University Press
Release Date : 1994-05-26
The Causes Of Molecular Evolution written by John H. Gillespie and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-05-26 with Science categories.
This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.
Molecular Evolution And Phylogenetics
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Author : Masatoshi Nei
language : en
Publisher: Oxford University Press, USA
Release Date : 2000
Molecular Evolution And Phylogenetics written by Masatoshi Nei and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Language Arts & Disciplines categories.
This is a treatment of the statistical methods used in molecular evolution and phylogenetics study. Newly developed statistical methods for studying the molecular clock, adaptive evolution and inference of ancestral amino acid sequences are also included.
Bioinformatics And Molecular Evolution
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Author : Paul G. Higgs
language : en
Publisher: John Wiley & Sons
Release Date : 2013-04-30
Bioinformatics And Molecular Evolution written by Paul G. Higgs and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-30 with Science categories.
In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text: provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding is accompanied by a dedicated website - www.blackwellpublishing.com/higgs - containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM). This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.
Computational Molecular Evolution
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Author : Ziheng Yang
language : en
Publisher: OUP Oxford
Release Date : 2006-10-05
Computational Molecular Evolution written by Ziheng Yang and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-05 with Science categories.
The field of molecular evolution has experienced explosive growth in recent years due to the rapid accumulation of genetic sequence data, continuous improvements to computer hardware and software, and the development of sophisticated analytical methods. The increasing availability of large genomic data sets requires powerful statistical methods to analyse and interpret them, generating both computational and conceptual challenges for the field. Computational Molecular Evolution provides an up-to-date and comprehensive coverage of modern statistical and computational methods used in molecular evolutionary analysis, such as maximum likelihood and Bayesian statistics. Yang describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes. The book emphasizes essential concepts rather than mathematical proofs. It includes detailed derivations and implementation details, as well as numerous illustrations, worked examples, and exercises. It will be of relevance and use to students and professional researchers (both empiricists and theoreticians) in the fields of molecular phylogenetics, evolutionary biology, population genetics, mathematics, statistics and computer science. Biologists who have used phylogenetic software programs to analyze their own data will find the book particularly rewarding, although it should appeal to anyone seeking an authoritative overview of this exciting area of computational biology.
Molecular Evolution
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Author : Duane L. Rohlfing
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular Evolution written by Duane L. Rohlfing and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Formuch of his professional career, Sidney W. Fox has devoted his thought and research to studies of molecular evolution. MOLECULAR EVOLUTION: PREBIOLOGICAL AND BIOLOGICAL is a dedicatory vol ume of thirty-five contributed papers commemorating, on the occasion of his sixtieth birthday, his many achievements. The volume had its conception in the USSR (by AIO), had much of its development in the USA (by DLR) , and was made possible by the enthusi astic responses and enc·ouragements of fifty-eight contributors from ten nations and many disciplines. These numbers connote not only the es teem in which S. W. Fox is regarded, but also the international and in terdisciplinary nature of studies of molecular evolution. The term "molecular evolution" is often associated with abiotic or prebiotic evolution; it is also used to denote processes of biotic evolu tion at the molecular level. The point of merger of these two sub-areas, at "life," represents but one stage (albeit a very important one) in the total process of the evolution of matter, from hydrogen to Homo sapiens and beyond. This volume considers aspects of molecular evolution in this broader sense. Accordingly, the contributors include persons ex perienced in the prebiological and also the biological aspects of molecu lar evolution; several "outside" viewpoints are provided by persons whose principal interests lie in other diSCiplines. The contributions are both experimental and theoretical.
The Neutral Theory Of Molecular Evolution
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Author : Motoo Kimura
language : en
Publisher: Cambridge University Press
Release Date : 1983
The Neutral Theory Of Molecular Evolution written by Motoo Kimura and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Science categories.
This book is the first comprehensive treatment of this subject.
Molecular Evolution
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Author : Vadim A. Ratner
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Molecular Evolution written by Vadim A. Ratner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
In 1970, Manfred Eigen initiated the study of the origin of self-reproducing systems of macromolecules and their evolution. Large-scale nucleotide sequencing (with computer methods) was introduced from 1977. The authors of this book, the first edition of which appeared (in Russian) in 1985, have been engaged in the research of the evolution of molecular genetic regulatory systems ever since those pioneering years. The book considers many fundamental problems of molecular biology, evolution, molecular genetic organization, the structure and function of macromolecules, always with the underlying motive of developing a unified theory. It describes many original, theoretical results as well as computational methods.
Molecular Evolution
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Author : Ziheng Yang
language : en
Publisher: OUP Oxford
Release Date : 2014-05-15
Molecular Evolution written by Ziheng Yang and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-15 with Science categories.
Studies of evolution at the molecular level have experienced phenomenal growth in the last few decades, due to rapid accumulation of genetic sequence data, improved computer hardware and software, and the development of sophisticated analytical methods. The flood of genomic data has generated an acute need for powerful statistical methods and efficient computational algorithms to enable their effective analysis and interpretation. Molecular Evolution: a statistical approach presents and explains modern statistical methods and computational algorithms for the comparative analysis of genetic sequence data in the fields of molecular evolution, molecular phylogenetics, statistical phylogeography, and comparative genomics. Written by an expert in the field, the book emphasizes conceptual understanding rather than mathematical proofs. The text is enlivened with numerous examples of real data analysis and numerical calculations to illustrate the theory, in addition to the working problems at the end of each chapter. The coverage of maximum likelihood and Bayesian methods are in particular up-to-date, comprehensive, and authoritative. This advanced textbook is aimed at graduate level students and professional researchers (both empiricists and theoreticians) in the fields of bioinformatics and computational biology, statistical genomics, evolutionary biology, molecular systematics, and population genetics. It will also be of relevance and use to a wider audience of applied statisticians, mathematicians, and computer scientists working in computational biology.