Molecular Mechanisms In The Control Of Gene Expression


Molecular Mechanisms In The Control Of Gene Expression
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Molecular Mechanisms In The Control Of Gene Expression


Molecular Mechanisms In The Control Of Gene Expression
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Author : Donald P. Nierlich
language : en
Publisher: Elsevier
Release Date : 2013-10-22

Molecular Mechanisms In The Control Of Gene Expression written by Donald P. Nierlich and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.


Molecular Mechanisms in the Control of Gene Expression documents the proceedings of the ICN-UCLA conference on Molecular Mechanisms in the Control of Gene Expression, organized through the Molecular Biology Institute of UCLA, held in Keystone, Colorado, 21-26 March 1976. The conference focused on three topics: the action of repressors on specific nucleotide sequences in DNA; how DNA and histones are intertwined in eucaryotic chromosomes; and in the development of new techniques that appear to lift genes from complex genomes. The volume contains 65 chapters organized into nine parts. The papers in Part I examine the organization of prokaryotic and eukaryotic chromosomes. Part II presents studies on the interaction of RNA a polymerase and regulatory molecules with defined DNA sites. Parts III and IV focus on RNA polymerases of eukaryotes and the regulation of transcription in eukaryotic systems, respectively. Part V contains papers dealing with nucleic acid sequences, transcription, and processing. Part VI covers cellular aspects in the study of gene expression. Part VII takes up cloning while Part VIII is devoted to genetic analysis through restriction mapping and molecular cloning. Finally, Part IX summarizes the recent progress reported at the conference and also indicates some of the limitations that can be placed upon interpretation of data.



Molecular Mechanisms In The Control Of Gene Expression


Molecular Mechanisms In The Control Of Gene Expression
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Author : Donald P. Nierlich
language : en
Publisher:
Release Date : 1976

Molecular Mechanisms In The Control Of Gene Expression written by Donald P. Nierlich and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with categories.




Molecular Mechanisms In The Control Of Gene Expression


Molecular Mechanisms In The Control Of Gene Expression
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Author : Bonald P. Nierlich
language : en
Publisher:
Release Date : 1976

Molecular Mechanisms In The Control Of Gene Expression written by Bonald P. Nierlich and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with categories.




Molecular Mechanisms In The Control Of Gene Expression


Molecular Mechanisms In The Control Of Gene Expression
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Author : Donald P. Nierlich
language : en
Publisher:
Release Date : 1976

Molecular Mechanisms In The Control Of Gene Expression written by Donald P. Nierlich and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with categories.




Regulation Of Gene Expression


Regulation Of Gene Expression
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Author : Gary H. Perdew
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-17

Regulation Of Gene Expression written by Gary H. Perdew and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-17 with Science categories.


The use of molecular biology and biochemistry to study the regulation of gene expression has become a major feature of research in the biological sciences. Many excellent books and reviews exist that examine the experimental methodology employed in specific areas of molecular biology and regulation of gene expression. However, we have noticed a lack of books, especially textbooks, that provide an overview of the rationale and general experimental approaches used to examine chemically or disease-mediated alterations in gene expression in mammalian systems. For example, it has been difficult to find appropriate texts that examine specific experimental goals, such as proving that an increased level of mRNA for a given gene is attributable to an increase in transcription rates. Regulation of Gene Expression: Molecular Mechanisms is intended to serve as either a textbook for graduate students or as a basic reference for laboratory personnel. Indeed, we are using this book to teach a graduate-level class at The Pennsylvania State University. For more details about this class, please visit http://moltox. cas. psu. edu and select “Courses. ” The goal for our work is to provide an overview of the various methods and approaches to characterize possible mechanisms of gene regulation. Further, we have attempted to provide a framework for students to develop an understanding of how to determine the various mechanisms that lead to altered activity of a specific protein within a cell.



Mechanisms Of Gene Expression


Mechanisms Of Gene Expression
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Author : Robert O J Weinzierl
language : en
Publisher: World Scientific
Release Date : 1999-08-10

Mechanisms Of Gene Expression written by Robert O J Weinzierl and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-08-10 with Science categories.


A detailed knowledge of the mechanisms underlying the transcriptional control of gene expression is of fundamental importance to many areas of contemporary biomedical research, ranging from understanding basic issues (such as control of embryonic development) to practical applications in industry and medicine. Although elementary concepts of gene expression are described in all general molecular biology textbooks, the depth of coverage is often rather limited and recent discoveries are sometimes not adequately taken into consideration. This book presents much of the current thinking concerning molecular mechanisms of transcriptional control in a form easily accessible to undergraduates with an understanding of basic molecular biology concepts. It contains detailed information about the various pro- and eukaryotic transcriptional machineries that has recently become available through the combined efforts of geneticists, biochemists and structural biologists. The book will thus not only serve as an undergraduate text but also offer something new and interesting to more advanced readers and professional scientists who want to keep up to date with rapid advances in this field. Contents:RNA PolymerasesBasal Factors Recognize Promoters and Assemble the Pre-Initiation Transcription ComplexesGene-Specific Transcription FactorsCoactivators: Interface between Gene-Specific and Basal Transcription FactorsControl of RNA Elongation and TerminationRNAPI and RNAPIII Transcriptional MachineriesChromatinNuclear Matrix, Chromosome Scaffolds and Transcriptional FactoriesGene Expression Dynamics and Global Genome Transcription PatternsAppearing on the Horizon: Medical Applications Focusing on Transcriptional Control Mechanisms Readership: Undergraduate and graduate students in molecular biology, biochemistry and genetics. Keywords:Gene Expression;Genetics;Mechanisms;Basal Transcriptional Machinery



Chromatin And Gene Regulation


Chromatin And Gene Regulation
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Author : Bryan M. Turner
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15

Chromatin And Gene Regulation written by Bryan M. Turner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Science categories.


Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the mechanisms by which they operate is one of the most exciting and rapidly developing areas of modern biology. Chromatin is central both to the rapid changes in gene transcription by which cells respond to changes in their environment and also to the maintenance of gene expression patterns from one cell generation to the next. This book will be an invaluable guide to undergraduate and postgraduate students in the biological sciences and all those with an interest in the medical implications of aberrant gene expression.



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.




Prokaryotic Gene Expression


Prokaryotic Gene Expression
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Author : Simon Baumberg
language : en
Publisher: OUP Oxford
Release Date : 1999-05-27

Prokaryotic Gene Expression written by Simon Baumberg and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-05-27 with Science categories.


Prokaryotic gene expression is not only of theoretical interest but also of highly practical significance. It has implications for other biological problems, such as developmental biology and cancer, brings insights into genetic engineering and expression systems, and has consequences for important aspects of applied research. For example, the molecular basis of bacterial pathogenicity has implications for new antibiotics and in crop development. Prokaryotic Gene Expression is a major review of the subject, providing up-to-date coverage as well as numerous insights by the prestigious authors. Topics covered include operons; protein recognition of sequence specific DNA- and RNA-binding sites; promoters; sigma factors, and variant tRNA polymerases; repressors and activators; post-transcriptional control and attenuation; ribonuclease activity, mRNA stability, and translational repression; prokaryotic DNA topology, topoisomerases, and gene expression; regulatory networks, regulatory cascades and signal transduction; phosphotransfer reactions; switch systems, transcriptional and translational modulation, methylation, and recombination mechanisms; pathogenicity, toxin regulation and virulence determinants; sporulation and genetic regulation of antibiotic production; origins of regulatory molecules, selective pressures and evolution of prokaryotic regulatory mechanisms systems. Over 1100 references to the primary literature are cited. Prokaryotic Gene Expression is a comprehensive and authoritative review of current knowledge and research in the area. It is essential reading for postgraduates and researchers in the field. Advanced undergraduates in biochemistry, molecular biology, and microbiology will also find this book useful.



Gene Expression And Regulation


Gene Expression And Regulation
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Author : Jun Ma
language : en
Publisher: Springer
Release Date : 2010-12-24

Gene Expression And Regulation written by Jun Ma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-24 with Science categories.


This book offers a comprehensive look at the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. The focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.