Molecular Network Study Of Pituitary Adenomas
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Molecular Network Study Of Pituitary Adenomas
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Author : Xianquan Zhan
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-13
Molecular Network Study Of Pituitary Adenomas written by Xianquan Zhan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-13 with categories.
Molecular Pathology Of Pituitary Adenomas
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Author : Cristiana Tanase
language : en
Publisher: Elsevier
Release Date : 2011-11-16
Molecular Pathology Of Pituitary Adenomas written by Cristiana Tanase and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-16 with Medical categories.
The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies. Facilitates the understanding of the processes involved and how they are translated into therapy Illustrations are used to explain the complex mechanisms involved
Predictive Preventive And Personalised Medicine From Bench To Bedside
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Author : Halina Podbielska
language : en
Publisher: Springer Nature
Release Date : 2023-10-30
Predictive Preventive And Personalised Medicine From Bench To Bedside written by Halina Podbielska and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-30 with Medical categories.
This volume presents advanced bio/medical sciences with a particular value for translating research achievements into daily medical practice in the framework of Predictive, Preventive and Personalised Medicine (3PM/PPPM). First two decades of the 21st century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of patients diagnosed with cardiovascular diseases and the type 2 diabetes mellitus, breast, lung, liver and prostate malignancies, neurological, sleep, mood and eye disorders, amongst others. Consequent socio-economic burden is tremendous. Unprecedented decrease in age of maladaptive individuals has been reported. The absolute majority of expanding non-communicable disorders carry a chronic character, over a couple of years progressing from reversible suboptimal health conditions to irreversible severe pathologies and cascading collateral complications. The paradigm change from reactive to predictive preventive and personalised medicine is essential to promote population health by application of individualised patient profiling, multi-parametric analysis leading to cost-effective targeted prevention. To this end, inadequate data for risk assessment on speed and urgency of COVID-19, combined with increased globalization of human society, led to the rapid spread of COVID-19. Despite an abundance of digital methods that could be used in slowing or stopping this virus and future pandemics, the world remains unprepared, and lessons have not been learned from previous cases of pandemics. The book presents PPPM strategies which might be of great clinical utility for future pandemics. In a long-term way, a significantly improved healthcare economy is one of the clear benefits of the proposed paradigm shift; a tight collaboration between all stakeholders including scientific community, healthcare providers, patient organisations, policy-makers and educators is analysed for the smooth implementation of the 3PM concepts. Further issues linked to big data management and medical ethics have to be carefully treated in the context of application of artificial intelligence in medicine.
Proteomics Technologies And Applications
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Author : Ibrokhim Y. Abdurakhmonov
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-09-25
Proteomics Technologies And Applications written by Ibrokhim Y. Abdurakhmonov and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-25 with Science categories.
Proteomics Technologies and Applications reviews and describes the nature and application of molecules with proteins or peptides, and elucidates and predicts the possible molecular and physiological causes related to changing proteomic profiles. Chapters target various methods and tools available for analysis, detection, separation, quantification, and localization of cell proteomes of a biological system, which are helpful as biomarkers for various disease prognoses and diagnoses.
Refractory Pituitary Adenoma Current Challenges And Emerging Treatments
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Author : Renzhi Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-29
Refractory Pituitary Adenoma Current Challenges And Emerging Treatments written by Renzhi Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-29 with Medical categories.
The Pituitary
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Author : Shlomo Melmed
language : en
Publisher: Academic Press
Release Date : 2010-12-09
The Pituitary written by Shlomo Melmed and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-09 with Medical categories.
The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. - Presents a comprehensive, translational source of information about the pituitary in one reference work - Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches - Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders - Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches
Proteoforms
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Author : Xianquan Zhan
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-07-15
Proteoforms written by Xianquan Zhan and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-15 with Science categories.
A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and can lead to the discovery of reliable biomarkers and therapeutic targets for effective prediction, diagnosis, prognostic assessment, and therapy of disease. This book focuses on the concept, study, and applications of proteoforms. Chapters cover such topics as methodologies for identifying and preparing proteoforms, proteoform pattern alteration in pituitary adenomas, and proteoforms in leukemia.
Oxford Textbook Of Endocrinology And Diabetes
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Author : John Wass
language : en
Publisher: Oxford University Press
Release Date : 2022-03-10
Oxford Textbook Of Endocrinology And Diabetes written by John Wass and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-10 with Medical categories.
Now in its third edition, the Oxford Textbook of Endocrinology and Diabetes is an up-to-date, objective and comprehensive text that covers the full scope of endocrinology and diabetes. It contains wide ranging and pragmatic advice on diagnosis and clear guidelines for recommended management, while also covering the scientific principles that underlie the medical practice in this important field. The book has been re-organised into 15 overarching sections, with new sections on Endocrinology of Pregnancy and Management of the Transgender Patient included. All other sections have been extensively updated and restructured. Each chapter is written by an internationally acknowledged expert, relates basic science to evidence based guidelines and clinical management, and where appropriate offers an outline of the controversies in the subject. The textbook has an international focus and deals with subject matter applicable across the globe. The new edition has over 800 images complementing the extensive text and information provided. The book is a 'one-stop' text for trainees and consultants in Endocrinology and Diabetes, residents, those preparing for sub-specialty exams and other professionals allied to the area who need to gain an understanding of the field. It acts as both a point of reference for the experienced consultant as well as a trusted training resource. Purchase of the print work also includes full access to the online edition of the textbook for the life of the edition.
Plasticity In The Vertebrate Pituitary Including Regulatory Mechanisms
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Author : Finn-Arne Weltzien
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-14
Plasticity In The Vertebrate Pituitary Including Regulatory Mechanisms written by Finn-Arne Weltzien and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-14 with Medical categories.
The Advances Of Endoscopic Skull Base Tumor Surgery From Basic To Clinical Research
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Author : Peng Zhao
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-09
The Advances Of Endoscopic Skull Base Tumor Surgery From Basic To Clinical Research written by Peng Zhao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-09 with Medical categories.
For neurosurgeons, skull base neurosurgery is as complex, dangerous, challenging, and charming as Mount Everest. The vigorous development of neuroendoscopy has opened a new perspective for skull base neurosurgery. Due to the special structure of skull base, there are often "blind spots" left out by microscope, while neuroendoscopy is the promising technology to overcome the defects. With its minimally invasive advantages, neuroendoscopy is gradually becoming popular in neurosurgical operation. In recent years, neuroendoscopic surgery for pituitary adenoma, the anterior skull base and sellar turcica meningioma, clivus chordoma and tumors in the foramen magnum area have been reported, as well as for atlantoaxial lesions. Neuroendoscopy for skull base midline surgical area has attracted accumulating attention, and its application is widely used in basic and clinical research.