Molecular Structure And Function Of The Tight Junction
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Molecular Structure And Function Of The Tight Junction
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Author : Michael Fromm
language : en
Publisher: John Wiley & Sons
Release Date : 2009-06-22
Molecular Structure And Function Of The Tight Junction written by Michael Fromm and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-22 with Medical categories.
Aim of this volume is to clarify the relationship between molecular structure and function of tight junction proteins, as well as their regulation and their role in diseases. Current research may form a basis for future diagnostic and therapeutic approaches to diseases which seem to have not much in common but are characterized by defects of organ barriers, like Crohn's disease, renal hypertension, inner ear deafness, and cancerous diseases. Topics include the functions of distinct tight junction proteins as barrier or channel formers for solutes and water, characteristics of the tight junction in inflammatory bowel diseases, posttranslational modifications of tight junction proteins, the relation between renal tight junction proteins and blood pressure control, and the molecular structure of claudin-claudin interactions NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Molecular Structure And Function Of The Tight Junction
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Author : Jörg-Dieter Schulzke
language : en
Publisher:
Release Date : 2009
Molecular Structure And Function Of The Tight Junction written by Jörg-Dieter Schulzke and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Tight junctions (Cell biology) categories.
Tight Junctions
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Author : Marcelino Cereijido
language : en
Publisher: CRC Press
Release Date : 2001-06-26
Tight Junctions written by Marcelino Cereijido and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-26 with Medical categories.
As the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field. Since its publication in 1992, there has been an explosion of information about tight junctions, particularly in the area of molecular structure, cell and molecular bio
Tight Junctions
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Author : Lorenza González-Mariscal
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-26
Tight Junctions written by Lorenza González-Mariscal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-26 with Science categories.
This book provides state-of-the-art insight into Tight Junctions (TJs), the intersection of epithelial and endothelial cells in various tissues. Opening with an analysis of the evolutionary development of a transporting epithelium in early metazoans, the book describes current understanding of TJ structure and function information, including evidence supporting the presence of ion channels within TJs. Also deals with TJs of central nervous system myelin and at the blood brain barrier.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Tight Junctions In Inflammation And Cancer
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Author : Ajaz A. Bhat
language : en
Publisher: Springer Nature
Release Date : 2023-10-12
Tight Junctions In Inflammation And Cancer written by Ajaz A. Bhat and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-12 with Science categories.
This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.
Tight Junctions In Cancer Metastasis
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Author : Tracey A. Martin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-02-26
Tight Junctions In Cancer Metastasis written by Tracey A. Martin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-26 with Medical categories.
There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians.
Molecular Mechanisms Of Epithelial Cell Junctions
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Author : Sandra Citi
language : en
Publisher:
Release Date : 1994
Molecular Mechanisms Of Epithelial Cell Junctions written by Sandra Citi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Cell adhesion categories.
This text examines past and current progress on the structural, biochemical and molecular characterization of specialized cell-cell junctions in various types of epithelial tissue. Special attention is devoted to the recent characterization of specific protein components of junctions, and to questions of structure/function relationships in development, disease and phylogeny in epithelial junctions.
A Laboratory Guide To The Tight Junction
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Author : Jianghui Hou
language : en
Publisher: Academic Press
Release Date : 2020-04-24
A Laboratory Guide To The Tight Junction written by Jianghui Hou and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-24 with Science categories.
A Laboratory Guide to the Tight Junction offers broad coverage of the unique methods required to investigate its characteristics. The methods are described in detail, including its biochemical and biophysical principles, step-by-step process, data analysis, troubleshooting, and optimization. The coverage includes various cell, tissue, and animal models. Chapter 1 provides the foundations of cell biology of tight junction. Chapter 2 covers the Biochemical approaches for paracellular channels and is followed by chapter 3 providing the Biophysical approaches. Chapter 4 describes and discusses Histological approaches for tissue fixation and preparation. Chapter 5 discusses Light microscopy, while chapter 6 presents Electron microscopic approaches. Chapter 7 covers Transgenic manipulation in cell cultures, including DNA and siRNA, Mutagenesis, and viral infection. Chapter 8 covers transgenic manipulation in mice, including: Knockout, Knockin, siRNA knockdown, GFP/LacZ reporter, and overexpression. The final chapter discusses the future developments of new approaches for tight junction research. Researchers and advanced students in bioscience working on topics of cell junction, ion channel and membrane protein will benefit from the described methods. Clinicians and pathologists interested in tissue barrier diseases will also benefit from the biochemical and biophysical characterization of tight junctions in organ systems, and their connection to human diseases. Provides consistent and detailed research methods Covers various cell, tissue and animal models Includes step-by-step guidance from beginner to sophisticated levels
Biology Of The Integument
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Author : J. Bereiter-Hahn
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biology Of The Integument written by J. Bereiter-Hahn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The integument plays an important role in the survival of meta zoans by separating and protecting them from a hostile environ ment. Its function ranges from protection against injury and in fection; partlcipation in the regulation of body temperature and water balance, to respiratory activity, monitoring of the environ ment and production of signals related to behaviour. All these result from specific structural, biochemical and physiological properties of intra-and extracellular components of the integu ment. Thus its characterization can be best accomplished by a multidisciplinary approach with authors specialized in different fields of science. This multi-author book, in two volumes, provides an up-to date survey of the literature. The first volume deals with the integument of invertebrates, the second with that of vertebrates, both organized primarily on a phylum basis. As the level of knowledge on the integument of phyla differs considerably, the information provided is correspondingly either limited or con densed. For some of the smaller groups of invertebrates little information is available, as often only a few electron micrographs are to be found in the literature; on the other hand, from the large body of knowledge existing for vertebrates, particularly for mammals, no complete overview can be provided, but publica tions giving access to further information have been reviewed critically.