Morpho Molecular Ex Vivo Detection And Grading Of Non Muscle Invasive Bladder Cancer Using Forward Imaging Probe Based Multimodal Optical Coherence Tomography And Raman Spectroscopy
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Morpho Molecular Ex Vivo Detection And Grading Of Non Muscle Invasive Bladder Cancer Using Forward Imaging Probe Based Multimodal Optical Coherence Tomography And Raman Spectroscopy
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Author : Fabian Placzek
language : en
Publisher:
Release Date : 2020
Morpho Molecular Ex Vivo Detection And Grading Of Non Muscle Invasive Bladder Cancer Using Forward Imaging Probe Based Multimodal Optical Coherence Tomography And Raman Spectroscopy written by Fabian Placzek and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Abstract: Non-muscle-invasive bladder cancer affects millions of people worldwide, resulting in significant discomfort to the patient and potential death. Today, cystoscopy is the gold standard for bladder cancer assessment, using white light endoscopy to detect tumor suspected lesion areas, followed by resection of these areas and subsequent histopathological evaluation. Not only does the pathological examination take days, but due to the invasive nature, the performed biopsy can result in significant harm to the patient. Nowadays, optical modalities, such as optical coherence tomography (OCT) and Raman spectroscopy (RS), have proven to detect cancer in real time and can provide more detailed clinical information of a lesion, e.g. its penetration depth (stage) and the differentiation of the cells (grade). In this paper, we present an ex vivo study performed with a combined piezoelectric tube-based OCT-probe and fiber optic RS-probe imaging system that allows large field-of-view imaging of bladder biopsies, using both modalities and co-registered visualization, detection and grading of cancerous bladder lesions. In the present study, 119 examined biopsies were characterized, showing that fiber-optic based OCT provides a sensitivity of 78% and a specificity of 69% for the detection of non-muscle-invasive bladder cancer, while RS, on the other hand, provides a sensitivity of 81% and a specificity of 61% for the grading of low- and high-grade tissues. Moreover, the study shows that a piezoelectric tube-based OCT probe can have significant endurance, suitable for future long-lasting in vivo applications. These results also indicate that combined OCT and RS fiber probe-based characterization offers an exciting possibility for label-free and morpho-chemical optical biopsies for bladder cancer diagnostics
Reviews In Cancer Imaging And Image Directed Interventions
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Author : Omar Sultan Al-Kadi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-25
Reviews In Cancer Imaging And Image Directed Interventions written by Omar Sultan Al-Kadi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-25 with Medical categories.
Ai
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Author : 周立婕
language : zh-CN
Publisher: 財團法人國家實驗研究院科技政策研究與資訊中心
Release Date : 2024-06-01
Ai written by 周立婕 and has been published by 財團法人國家實驗研究院科技政策研究與資訊中心 this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-01 with Juvenile Nonfiction categories.
研究前沿的識別分析至關重要，有助於監測熱門的研究及發掘具有潛力的研究主題，並了解當前知識與技術發展的現況，在學術層級，研究人員得以快速掌握知識發展趨勢，進而擬定研究主題；在產業層級，可作為技術與商業布局之即時參考；在社會層級，政府在制定政策時能擁有更精準的參考依據，以進行國家資源分配、研究能量布署、法規制定等決策行為，進而提升國際競爭力。 本研究旨在運用書目計量方法建立一研究前沿識別架構，並發展兩種的前沿技術識別模組，分別為知識影響力構面及知識品質與來源構面，透過線性關係描述AI 技術中的知識流動與研究前沿，以識別潛力技術所在，有助於各界更清晰地辨識與理解新興AI 技術的發展趨勢，並為往後其他領域的識別提供了參考架構。基於本研究之研究前沿識別架構，識別出AI五大重點研究主題，分別為機器學習、深度學習、卷積神經網絡、分類技術與特徵擷取，在機器學習方面，研究聚焦於演算法優化、影像處理、多模態機器學習等，並應用於醫學、城市規劃、金融等領域。深度學習的研究方向包括疾病診斷、機械故障偵測、金融和災害預測，並關注執行策略的優化。卷積神經網絡研究注重於物件偵測、圖像分割、特徵識別等，多應用於機械故障、醫學影像、城市建築等。分類技術則強調分類演算法和特徵提取的效能提升，並廣泛應用於地理環境、地球科學、光譜學等。特徵擷取技術集中在臉部辨識、可見光與紅外線影像的分類與融合，並應用於智慧故障診斷、醫學影像等。
Make Life Visible
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Author : Yoshiaki Toyama
language : en
Publisher: Springer Nature
Release Date : 2019-10-02
Make Life Visible written by Yoshiaki Toyama and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-02 with Medical categories.
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.
Textbook Of Oral Cancer
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Author : Saman Warnakulasuriya
language : en
Publisher: Springer Nature
Release Date : 2020-02-22
Textbook Of Oral Cancer written by Saman Warnakulasuriya and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-22 with Medical categories.
This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.
Lasers And Current Optical Techniques In Biology
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Author : Giuseppe Palumbo
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31
Lasers And Current Optical Techniques In Biology written by Giuseppe Palumbo and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Science categories.
The introduction of innovative light sources, fibre laser sources and light emitting diodes, is opening unexpected perspectives into optical techniques and is promising new exciting applications in the field of biomedicine. Lasers and Current Optical Techniques in Biology aims to provide an overview of light sources, together with an extensive and authoritative description of the optical techniques in bio-medicine. This book is designed to give biomedical researchers a strong feel for the capability of physical approaches, promote new interdisciplinary interests and persuade more practitioners to take advantage of optical techniques. Current developments in a variety of optical techniques, including Near-Infra Red Spectroscopy, and traditional and advanced fluorescence techniques are covered, ranging from those that are becoming common practice to those that need much more experimentation before they can be accepted as real breakthroughs. Further topics include optical coherence tomography and its variations, polarised light imaging and, principle laser and lamp sources- a usually fragmentary topic, often dispersed among specialist publications. The wide range of topics covered make Lasers and Current Optical Techniques in Biology of interest to a diverse range of scientific communities.
Interventions In Pulmonary Medicine
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Author : Jose Pablo Díaz-Jimenez
language : en
Publisher: Springer
Release Date : 2017-11-21
Interventions In Pulmonary Medicine written by Jose Pablo Díaz-Jimenez and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-21 with Medical categories.
This new edition offers comprehensive coverage of all areas of interventional pulmonology, a minimally invasive endoscopic method for diagnosing and treating lung disorders. The text is divided into eight sections on the major areas of interventional pulmonology, including basic endoscopy, lung cancer staging, and interventional bronschoscopy in asthma and emphysema. Chapters then explore specific procedures and techniques, including medical thoracoscopy, flexible and rigid bronchoscopy, endobronchial ultrasound, and electromagnetical navigation with coverage of history, indications and contraindications, and up-to-date evidence-based reviews. In recent years there have been many advances in interventional pulmonology, the most significant relating to lung cancer early diagnosis and late-stage treatment. Two new chapters on lung cancer epidemiologic changes and personalized lung cancer treatment explore new methods for maximizing patient care for an increasingly prevalent disease. This inclusive volume concludes with a look towards the future of interventional pulmonology and experimental techniques currently being tested. Interventions in Pulmonary Medicine, Second Edition, is a must have for pulmonologists, endoscopists, pulmonary oncologists, ENT physicians, thoracic surgeons, anesthesiologists, and intensive care specialists and their teams.
Imaging In Oncological Urology
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Author : Jean J. M. C. H. Rosette
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-11-23
Imaging In Oncological Urology written by Jean J. M. C. H. Rosette and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-23 with Medical categories.
A hugely important book that details significant changes in imaging in oncological conditions related to the bladder, prostate and kidneys. The sole focus is on oncology in urology, mainly Ultrasound and MRI, with organ-oriented topics. The latest technologies on imaging are included to better identify carcinomatous lesions and lymph node metastases. Each chapter includes a section that outlines the optimal imaging approach, providing an algorithm for imaging per disease entity, and according to the evidence-based chronological and diagnostic follow-up.
8th European Medical And Biological Engineering Conference
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Author : Tomaz Jarm
language : en
Publisher: Springer Nature
Release Date : 2020-11-29
8th European Medical And Biological Engineering Conference written by Tomaz Jarm and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-29 with Technology & Engineering categories.
This book aims at informing on new trends, challenges and solutions, in the multidisciplinary field of biomedical engineering. It covers traditional biomedical engineering topics, as well as innovative applications such as artificial intelligence in health care, tissue engineering , neurotechnology and wearable devices. Further topics include mobile health and electroporation-based technologies, as well as new treatments in medicine. Gathering the proceedings of the 8th European Medical and Biological Engineering Conference (EMBEC 2020), held on November 29 - December 3, 2020, in Portorož, Slovenia, this book bridges fundamental and clinically-oriented research, emphasizing the role of education, translational research and commercialization of new ideas in biomedical engineering. It aims at inspiring and fostering communication and collaboration between engineers, physicists, biologists, physicians and other professionals dealing with cutting-edge themes in and advanced technologies serving the broad field of biomedical engineering.
Anesthesiology
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Author : Linda S. Aglio
language : en
Publisher: Springer
Release Date : 2017-07-25
Anesthesiology written by Linda S. Aglio and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-25 with Medical categories.
Divided into twelve sections that cover the entirety of anesthetic practice, this is a case-based, comprehensive review of anesthesiology that covers the basics of anesthetic management and reflects all new guidelines and recently developed standards of care. Each chapter of Anesthesiology: Clinical Case Reviews begins with a specific clinical problem or a clinical case scenario, followed by concise discussions of preoperative assessment, intraoperative management, and postoperative pain management. In addition to residents and fellows, this book is written for practicing anesthesiologists, student nurse anesthetists, and certified registered nurse anesthetists (CRNAs).