Multicellularity Views From Cellular Signaling And Mechanics

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Multicellularity Views From Cellular Signaling And Mechanics

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Author : Hiroaki Hirata
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-10

Multicellularity Views From Cellular Signaling And Mechanics written by Hiroaki Hirata and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-10 with Science categories.

Multicellularity

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Author : Karl J. Niklas
language : en
Publisher: MIT Press
Release Date : 2022-06-07

Multicellularity written by Karl J. Niklas and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-07 with Science categories.

Scholars consider the origins and consequences of the evolution of multicellularity, addressing a range of organisms, experimental protocols, theoretical concepts, and philosophical issues. The evolution of multicellularity raises questions regarding genomic and developmental commonalities and discordances, selective advantages and disadvantages, physical determinants of development, and the origins of morphological novelties. It also represents a change in the definition of individuality, because a new organism emerges from interactions among single cells. This volume considers these and other questions, with contributions that explore the origins and consequences of the evolution of multicellularity, addressing a range of topics, organisms, and experimental protocols. Each section focuses on selected topics or particular lineages that present a significant insight or challenge. The contributors consider the fossil record of the paleontological circumstances in which animal multicellularity evolved; cooptation, recurrent patterns, modularity, and plausible pathways for multicellular evolution in plants; theoretical approaches to the amoebozoa and fungi (cellular slime molds having long provided a robust model system for exploring the evolution of multicellularity), plants, and animals; genomic toolkits of metazoan multicellularity; and philosophical aspects of the meaning of individuality in light of multicellular evolution. Contributors Maja Adamska, Argyris Arnellos, Juan A. Arias, Eugenio Azpeitia, Mariana Benítez, Adriano Bonforti, John Tyler Bonner, Peter L. Conlin, A. Keith Dunker, Salva Duran-Nebreda, Ana E. Escalante, Valeria Hernández-Hernández, Kunihiko Kaneko, Andrew H. Knoll, Stephan G. König, Daniel J. G. Lahr, Ottoline Leyser, Alan C. Love, Raul Montañez, Emilio Mora van Cauwelaert, Alvaro Moreno, Vidyanand Nanjundiah, Aurora M. Nedelcu, Stuart A. Newman, Karl J. Niklas, William C. Ratcliff, Iñaki Ruiz-Trillo, Ricard Solé

Cellular Mechanics And Biophysics

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Author : Claudia Tanja Mierke
language : en
Publisher: Springer Nature
Release Date : 2020-10-30

Cellular Mechanics And Biophysics written by Claudia Tanja Mierke and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-30 with Science categories.

This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.

Mechanotransduction

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Author : Paul A. Sundaram
language : en
Publisher: Academic Press
Release Date : 2020-11-18

Mechanotransduction written by Paul A. Sundaram and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-18 with Technology & Engineering categories.

Mechanotransduction: Cell Signaling to Cell Response covers the cell machinery responsible for the process of mechanotransduction and the manner in which cells respond to an external mechanical stimulus. The effect of mechanical stimulus on individual cells and entire tissues is discussed, with an emphasis on the practical results of this physiological process. Mechanotransduction of stem cells and cancerous cells are also covered, along with future directions in this yet nascent field. This book gives insights on basic processes that occur (or may occur) in the human body as a result of the application of mechanical stimulus. It is ideal for both biomedical engineers and biologists, and is an ideal resource for teaching. It provides a current state of conceptual and practical aspects of the field and will enable students and professionals to venture further into this incipient area which is of fundamental importance to biomedical engineering and biology fields. - Covers fundamental concepts of signaling in cells as a result of mechanical stimulus - Includes the physiological results of mechanical stimulus on the human body - Explores the advantages of mechanical loads on the human body

Comprehensive Biophysics

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Author :
language : en
Publisher: Academic Press
Release Date : 2012-04-12

Comprehensive Biophysics written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-12 with Science categories.

Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource

Cell And Matrix Mechanics

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Author : Roland Kaunas
language : en
Publisher: CRC Press
Release Date : 2014-10-23

Cell And Matrix Mechanics written by Roland Kaunas and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-23 with Medical categories.

Explores a Range of Multiscale Biomechanics/Mechanobiology Concepts Cell and Matrix Mechanics presents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forces in cell–matrix interactions. Providing material in each chapter that builds on the previous chapters, it effectively integrates length scales and contains, for each length scale, key experimental observations and corresponding quantitative theoretical models. Summarizes the Three Hierarchical Levels of Cell Mechanics The book contains 14 chapters and is organized into three sections. The first section focuses on the molecular level, the second section details mechanics at the cellular level, and the third section explores cellular mechanics at the tissue level. The authors offer a thorough description of the roles of mechanical forces in cell and tissue biology, and include specific examples. They incorporate descriptions of associated theoretical models, and provide the data and modeling framework needed for a multi-scale analysis. In addition, they highlight the pioneering studies in cell–matrix mechanics by Albert K. Harris. The topics covered include: The passive and active mechanical properties of cytoskeletal polymers and associated motor proteins along with the behavior of polymer networks The mechanical properties of the cell membrane, with an emphasis on membrane protein activation caused by membrane forces The hierarchical organization of collagen fibrils, revealing that a delicate balance exists between specific and nonspecific interactions to result in a structure with semicrystalline order as well as loose associations The roles of matrix mechanical properties on cell adhesion and function along with different mechanical mechanisms of cell–cell interactions The effects of mechanical loading on cell cytoskeletal remodeling, summarizing various modeling approaches that explain possible mechanisms regulating the alignment of actin stress fibers in response to stretching The mechanical testing of cell-populated collagen matrices, along with theory relating the passive and active mechanical properties of the engineered tissues Cell migration behavior in 3-D matrices and in collective cell motility The role of mechanics in cartilage development The roles of both cellular and external forces on tissue morphogenesis The roles of mechanical forces on tumor growth and cancer metastasis Cell and Matrix Mechanics succinctly and systematically explains the roles of mechanical forces in cell–matrix biology. Practitioners and researchers in engineering and physics, as well as graduate students in biomedical engineering and mechanical engineering related to mechanobiology, can benefit from this work.

Introduction For Liver 3d Bioprinting Book 1

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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date : 2024-05-19

Introduction For Liver 3d Bioprinting Book 1 written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-19 with Medical categories.

The field of 3D bioprinting is rapidly evolving, offering unprecedented opportunities for medical and scientific advancements. "Introduction for Liver 3D Bioprinting – Book 1: Introduction to Cell Biology" is the first volume in a comprehensive series dedicated to exploring the intricate relationship between cellular biology and 3D bioprinting technology, specifically focusing on the liver. This book serves as a foundational text, aiming to bridge the gap between basic cell biology and its application in bioprinting. Understanding the principles of cell biology is crucial for anyone involved in tissue engineering, regenerative medicine, and 3D bioprinting, as it provides the essential knowledge needed to manipulate and cultivate cells effectively. In this volume, we delve into various aspects of cell biology, including the mechanisms of cellular processes, the roles of different cellular structures, and the intricacies of cellular signaling pathways. These topics are meticulously chosen to provide a broad yet detailed overview that sets the stage for more specialized discussions in subsequent volumes. Our goal is to equip researchers, students, and professionals with the knowledge required to innovate and excel in the field of 3D bioprinting. Each chapter is designed to build a strong conceptual framework, facilitating a deeper understanding of how cellular functions can be harnessed and manipulated for bioprinting applications. As you embark on this journey through the cellular world, we hope this book will inspire new ideas, foster scientific curiosity, and contribute to the growing body of knowledge in the field of bioprinting. Whether you are a seasoned researcher or new to the subject, this text aims to provide valuable insights and a solid foundation in cell biology, essential for advancing the science and application of 3D bioprinting. Thank you for joining us in exploring the fascinating intersection of cell biology and 3D bioprinting. We look forward to seeing the innovative solutions and breakthroughs that will emerge from your understanding and application of the concepts presented in this book.

Cell Adhesion And Migration In The Development Of Multicellular Organisms

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Author : Takaaki Matsui
language : en
Publisher: Frontiers Media SA
Release Date : 2019-01-24

Cell Adhesion And Migration In The Development Of Multicellular Organisms written by Takaaki Matsui and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-24 with categories.

During development, cells are generated at specific locations within the embryo and then migrate into their destinations. At their destinations, they assemble together through cell adhesions, eventually leading to the formation of tissues and organs. In some cases, orchestration of cell adhesion and migration produces the global movement of cell groups, called collective cell migration, which is also required for the development of basic tissue structures such as spheres, clusters, and vesicles in the morphogenetic processes of development. Therefore, individual regulation and orchestration of cell adhesion and migration are quite important for appropriate tissue/organ formation during development. However, how cell adhesion and migration are regulated, and orchestrated during development? How cell adhesion and migration affects tissue formation during development? To answer these questions, we assembled several review and research articles in this eBook. By assembling these articles, we could explore the presence of core regulatory mechanisms and deepen the current understanding of cell adhesion and migration during the development of multicellular organisms.

Nano Biomaterials In Tissue Repair And Regeneration

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Author : Necdet Sağlam
language : en
Publisher: Springer Nature
Release Date : 2024-11-22

Nano Biomaterials In Tissue Repair And Regeneration written by Necdet Sağlam and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-22 with Science categories.

This book covers the characterization of nano-biomaterials in tissue repair and regeneration which are materials designed to interact with biological systems to restore and regenerate damaged tissues. These materials serve as scaffolds that mimic the natural extracellular matrix (ECM), providing structural support and biochemical cues necessary for cellular activities. The physical and chemical properties of biomaterials are tailored to specific applications, such as bone regeneration, cartilage repair, wound healing, and organ transplantation. Biomaterials influence cell behavior and tissue formation by controlling factors like mechanical strength, porosity, and surface topography. This book provides an overview of the topic from the biomaterials’ characterization point of view and is suitable for students, academics, and clinical practitioners who are interested in the advancements of regenerative medicine.

First Signals

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Author : John Tyler Bonner
language : en
Publisher: Princeton University Press
Release Date : 2009-09-11

First Signals written by John Tyler Bonner and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-11 with Science categories.

The enormous recent success of molecular developmental biology has yielded a vast amount of new information on the details of development. So much so that we risk losing sight of the underlying principles that apply to all development. To cut through this thicket, John Tyler Bonner ponders a moment in evolution when development was at its most basic--the moment when signaling between cells began. Although multicellularity arose numerous times, most of those events happened many millions of years ago. Many of the details of development that we see today, even in simple organisms, accrued over a long evolutionary timeline, and the initial events are obscured. The relatively uncomplicated and easy-to-grow cellular slime molds offer a unique opportunity to analyze development at a primitive stage and perhaps gain insight into how early multicellular development might have started. Through slime molds, Bonner seeks a picture of the first elements of communication between cells. He asks what we have learned by looking at their developmental biology, including recent advances in our molecular understanding of the process. He then asks what is the most elementary way that polarity and pattern formation can be achieved. To find the answer, he uses models, including mathematical ones, to generate insights into how cell-to-cell cooperation might have originated. Students and scholars in the blossoming field of the evolution of development, as well as evolutionary biologists generally, will be interested in what Bonner has to say about the origins of multicellular development--and thus of the astounding biological complexity we now observe--and how best to study it.