Multidimensional Liquid Chromatography
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Multidimensional Liquid Chromatography
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Author : Steven A. Cohen
language : en
Publisher: John Wiley & Sons
Release Date : 2008-05-09
Multidimensional Liquid Chromatography written by Steven A. Cohen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-09 with Science categories.
Multidimensional Liquid Chromatography (MDLC) is a very powerful separation technique for analyzing exceptionally complex samples in one step. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help you perform very difficult separations of complex samples, this reference includes chapters contributed by leading experts or teams of experts.
Multidimensional Chromatography
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Author : Luigi Mondello
language : en
Publisher: John Wiley & Sons
Release Date : 2002-02-15
Multidimensional Chromatography written by Luigi Mondello and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-02-15 with Science categories.
Concentrates on the broad field of multidimensional chromatography and its applications in various areas, including pharmaceutical, industrial, environmental, biological and petroleum. Presents information for using multidimensional chromatography in the analytical laboratory. Contains invaluable information put together from the experience and research activities of the authors including Keith Bartle - a pioneer in multidimensional chromatography. First book to discuss all multidimensional techniques Covers a subject area that is part of the exploding field of hypenated techniques Includes a general introduction to all areas of the subject followed by applications
High Performance Liquid Chromatography
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Author : Sandie Lindsay
language : en
Publisher: John Wiley & Sons
Release Date : 1992-07-27
High Performance Liquid Chromatography written by Sandie Lindsay and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-07-27 with Science categories.
High performance liquid chromatography is the most powerful of all the chromatographic techniques, often achieving separations and analyses that would be difficult or impossible with other forms of chromatography. This study and training text examines the concepts and techniques used in this field. A selection of literature available from equipment manufacturers is included along with a brief review of some more specialized topics.
Handbook Of Advanced Chromatography Mass Spectrometry Techniques
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Author : Michal Holcapek
language : en
Publisher: Elsevier
Release Date : 2017-09-07
Handbook Of Advanced Chromatography Mass Spectrometry Techniques written by Michal Holcapek and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-07 with Technology & Engineering categories.
Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques. - Includes UHPLC, HILIC, nano-liquid chromatographic separations, two-dimensional LC-MS (LCxLC), multiple parallel MS, 2D-GC (GCxGC) methodologies for lipids analysis, and more - Contains both practical and theoretical knowledge, providing core understanding for implementing modern chromatographic and mass spectrometric techniques - Presents chapters on the most popular and fastest-growing new techniques being implemented in diverse areas of research
Multidimensional Chromatography
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Author : Hernan J. Cortes
language : en
Publisher: CRC Press
Release Date : 2020-07-24
Multidimensional Chromatography written by Hernan J. Cortes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-24 with Science categories.
This book summarizes all the important aspects of multidimensional separations, providing information on gas, liquid and thin-layer chromatography, as well as the techniques and applications of supercritical fluid chromatography in the multidimensional mode.
Optimization In Hplc
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Author : Stavros Kromidas
language : en
Publisher: John Wiley & Sons
Release Date : 2021-11-08
Optimization In Hplc written by Stavros Kromidas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-08 with Science categories.
Learn to maximize the performance of your HPLC or UHPLC system with this resource from leading experts in the field Optimization in HPLC: Concepts and Strategies delivers tried-and-tested strategies for optimizing the performance of HPLC and UHPLC systems for a wide variety of analytical tasks. The book explains how to optimize the different HPLC operation modes for a range of analyses, including small molecules, chiral substances, and biomolecules. It also shows readers when and how computational tools may be used to optimize performance. The practice-oriented text describes common challenges faced by users and developers of HPLC and UHPLC systems, as well as how those challenges can be overcome. Written for first-time and experienced users of HPLC technology and keeping pace with recent developments in HPLC instrumentation and operation modes, this comprehensive guide leaves few questions unanswered. Readers will also benefit from the inclusion of: A thorough introduction to optimization strategies for different modes and uses of HPLC, including working under regulatory constraints An exploration of computer aided HPLC optimization, including ChromSwordAuto and Fusion QbD A treatment of current challenges for HPLC users in industry as well as large and small analytical service providers Discussions of current challenges for HPLC equipment suppliers Tailor-made for analytical chemists, chromatographers, pharmacologists, toxicologists, and lab technicians, Optimization in HPLC: Concepts and Strategies will also earn a place on the shelves of analytical laboratories in academia and industry who seek a one-stop reference for optimizing the performance of HPLC systems.
Hydrophilic Interaction Chromatography
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Author : Bernard A. Olsen
language : en
Publisher: John Wiley & Sons
Release Date : 2012-12-14
Hydrophilic Interaction Chromatography written by Bernard A. Olsen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-14 with Science categories.
Discover how to use HILIC to analyze and better understand polar compounds An increasingly popular analytical method, hydrophilic interaction chromatography (HILIC) has the ability to retain and separate polar compounds that are often difficult to analyze by reversed-phase high-performance liquid chromatography (HPLC) or other analytical methods. Offering a comprehensive review, this book enables readers to develop a fundamental understanding of how HILIC works and then apply that knowledge to develop and implement a variety of practical applications. Hydrophilic Interaction Chromatography begins with discussions of HILIC retention mechanisms, stationary phases, and general method development. This sets the foundation for the book's extensive coverage of applications. The authors address unique separation challenges for bioanalytical, environmental, pharmaceutical, and biochemical applications. Moreover, there is a thorough discussion of HILIC in two-dimensional chromatography. With contributions from leading analytical scientists who have extensive experience in HILIC as well as HPLC, Hydrophilic Interaction Chromatography serves as a practical guide for researchers, featuring: Detailed examples of HILIC methods and development approaches Thorough explanations of retention mechanisms and the impact of stationary phase and mobile phase properties on separations Step-by-step guidance for developing efficient, sensitive, and robust HILIC methods References to the primary literature at the end of each chapter Hydrophilic Interaction Chromatography is written for scientists who use or develop analytical methods for the separation of polar compounds. In particular, these researchers will discover how HILIC can be used to analyze and better understand the composition of pharmaceutical, bioanalytical, biochemical, chemical, food, and environmental samples.
Multidimensional Chromatography
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Author : Cortes
language : en
Publisher: CRC Press
Release Date : 1989-12-11
Multidimensional Chromatography written by Cortes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-12-11 with Science categories.
Multidimensional Chromatography furnishes, for the first time, a comprehensive multidisciplined evaluation of state-of-the-art multidimensional chromatographic separation techniques -- including detailed discussions by leading international authorities on theoretical principles, instrumentation, and practical applications. Organized in a convenient manner, this current reference presents chapters dealing with multidimensional separations by thin-layer, gas, liquid, coupled LC-GC, supercritical fluid chromatographies, and extractions ... contains over 650 references and more than 150 illustrations ... offers large numbers of practical examples ... and introduces areas that require further study and suggest future trends. Multidimensional Chromatography is a timely, comprehensive source for analytical, bioanalytical, pharmaceutical, organic, physical, and industrial chemists and biochemists; chromatographers; pharmaceutical scientists; and professional seminars and graduate-level courses in the above disciplines. Book jacket.
Multidimensional Liquid Chromatography Separations
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Author : Jacob Nathan Fairchild
language : en
Publisher:
Release Date : 2010
Multidimensional Liquid Chromatography Separations written by Jacob Nathan Fairchild and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Many mixtures important to research consist of hundreds or even thousands of individual components of interest. These types of mixtures are far too complex to separate by a single chromatographic dimension in any reasonable amount of time. However, if a multidimensional approach is used, where a complex mixture is separated by an initial dimension, simpler fractions of that separation are collected and each of those fractions are analyzed individually, highly complex mixtures can be resolved in relatively short amounts of time. This dissertation serves as a guide to multidimensional chromatography, in particular, two-dimension liquid chromatography. There are many aspects of multidimensional separations that have been investigated to show its aspects, drawbacks and potential ability to separate highly complex mixtures. Measurements for the performance of multidimensional chromatography, the effects of the first and subsequent dimensions and the approaches to pairing dimensions are shown with experimental examples. Fundamental and practical features of multidimensional chromatography are explained as well as theoretical discussions on current and future multidimensional chromatography performance. Experimentally, very high peak capacities were obtained (ca. 7000) and an algorithm to predict how to best optimize a two-dimensional separation based on the time used and performance was created for designing experiments.
Hplc Of Peptides And Proteins
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Author : Marie-Isabel Aguilar
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03
Hplc Of Peptides And Proteins written by Marie-Isabel Aguilar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Science categories.
The introduction of high-performance liquid chromatography (HPLC) to the analysis of peptides and proteins some 25 years ago revolutionized the biological sciences by enabling the rapid and sensitive analysis of peptide and protein structure through the exquisite speed, sensitivity, and resolution that can be easily obtained. Today, HPLC in its various modes has become the pivotal technique in the characterization of peptides and proteins and currently plays a critical role in both our understanding of biological processes and in the development of peptide- and protein-based pharmaceuticals. The number of applications of HPLC in peptide and protein purification continues to expand at an extremely rapid rate. Solid-phase peptide synthesis and recombinant DNA techniques have allowed the production of large quantities of peptides and proteins that need to be highly purified. HPLC techniques are also used extensively in the isolation and characterization of novel proteins that will become increasingly important in the postgenomic age. The design of multidimensional purification schemes to achieve high levels of product purity further demonstrates the power of HPLC techniques not only in the characterization of cellular events, but also in the production of pepti- and protein-based therapeutics. HPLC continues to be at the heart of the analytical techniques with which scientists in both academia and in industry must arm themselves to be able to fully characterize the identity, purity, and potency of peptides and proteins.