Multiple Myeloma And Plasma Cell Dyscrasias
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Fast Facts Multiple Myeloma And Plasma Cell Dyscrasias
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Author : Karthik Ramasamy
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2017-01-09
Fast Facts Multiple Myeloma And Plasma Cell Dyscrasias written by Karthik Ramasamy and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-09 with Medical categories.
Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest advances in diagnostic tests and imaging - cytogenetics and genetic profiling - induction therapy prior to SCT - new lenalidomide- and bortezomib-based regimens - second-generation proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies treatments. This Fast Facts handbook provides a comprehensive overview of MM and other plasma cell dyscrasias, from bench to bedside, presenting the pathogenesis, diagnosis and treatment in the context of daily clinical practice. Contents: • Epidemiology and etiology Predisposing conditions associated with MM • Pathophysiology of MM and MGUS • Diagnosis, staging and monitoring of multiple myeloma • Genetics and multiple myeloma • Treatment of newly diagnosed multiple myeloma • Stem cell transplantation in multiple myeloma • Relapsed and refractory multiple myeloma • Bone disease and renal complications • AL amyloidosis • Rare plasma cell dyscrasias • Supportive care
Plasma Cell Dyscrasias
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Author : Aldo M. Roccaro
language : en
Publisher: Springer
Release Date : 2016-10-01
Plasma Cell Dyscrasias written by Aldo M. Roccaro and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-01 with Medical categories.
This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström’s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.
Multiple Myeloma And Plasma Cell Dyscrasias
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Author : Karthik Ramasamy
language : en
Publisher: Health Press (NM)
Release Date : 2015-08-03
Multiple Myeloma And Plasma Cell Dyscrasias written by Karthik Ramasamy and has been published by Health Press (NM) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-03 with Multiple myeloma categories.
Multiple Myeloma accounts for approximately 0.8% of cancers worldwide, with about 114 000 new cases each year. Rapid progress is being made in the development of new treatments and, although myeloma is incurable at present, survival has almost tripled over the past 10 years and it is now projected that a third of patients will survive more than 10 years after diagnosis. Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias emphasizes the importance of early diagnosis for a favourable outcome, covers the ever-increasing role of genetics in diagnosis and treatment, and discusses new and gold-standard treatments. A chapter on supportive care also features and briefs the healthcare professional on long-term outcomes and quality of life issues. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of myeloma and other plasma cell dyscrasias, from bench to bedside, putting the pathogenesis, diagnosis and treatment of these disorders in the context of daily clinical practice.
Fast Facts Multiple Myeloma And Plasma Cell Dyscrasias Lite Version
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Author : Karthik Ramasamy
language : en
Publisher:
Release Date : 2015-08-03
Fast Facts Multiple Myeloma And Plasma Cell Dyscrasias Lite Version written by Karthik Ramasamy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-03 with categories.
Multiple Myeloma accounts for approximately 0.8% of cancers worldwide, with about 114 000 new cases each year. Rapid progress is being made in the development of new treatments and, although myeloma is incurable at present, survival has almost tripled over the past 10 years and it is now projected that a third of patients will survive more than 10 years after diagnosis.Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias emphasizes the importance of early diagnosis for a favourable outcome, covers the ever-increasing role of genetics in diagnosis and treatment, and discusses new and gold-standard treatments. A chapter on supportive care also features and briefs the healthcare professional on long-term outcomes and quality of life issues. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of myeloma and other plasma cell dyscrasias, from bench to bedside, putting the pathogenesis, diagnosis and treatment of these disorders in the context of daily clinical practice.
Biology And Management Of Unusual Plasma Cell Dyscrasias
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Author : Todd M. Zimmerman
language : en
Publisher: Springer
Release Date : 2016-09-17
Biology And Management Of Unusual Plasma Cell Dyscrasias written by Todd M. Zimmerman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-17 with Medical categories.
This unique book focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others. The only book dedicated to this intriguing family of diseases, Biology and Management of Unusual Plasma Cell Dyscrasias will be a long-lasting reference for clinicians and scientists alike.
Contemporary Management Of Multiple Myeloma
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Author : Ravi Vij
language : en
Publisher: JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
Release Date : 2012-12-15
Contemporary Management Of Multiple Myeloma written by Ravi Vij and has been published by JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-15 with Medical categories.
This book "Contemporary Management of Multiple Myeloma" discusses in detail about the management of multiple myeloma. Multiple Myeloma is the second most common hematological malignancy in the United States. This book highlights the interplay between the malignant plasma cell and the microenvironment, and the role of genetic alterations, adhesion molecules and critical cytokines in this complex milieu. The first chapter of this book discusses epidemiology, etiology and pathogenesis of multiple myeloma. The clinical presentation of the common plasma cell dyscrasias and discuss the diagnostic and prognostic work-up with a highlighting on recent advances in chapters 3 and 4. Chapters from 5 to 9 focus on the therapeutic evolution that has occurred, and accumulate the landmark clinical trials that have changed clinical practice for up-front treatment of both transplant eligible and ineligible patients and for those with relapsed and refractory disease. These chapters also highlights on the important role of clinical research with stem cell transplantation, proteasome-inhibition and immunomodulatory drugs that form the backbone of our present day therapeutic armamentarium. Recommendations for response assessment and current understanding of the value of maximizing the depth of response in personalized therapy and patient segmentation are briefly explained in chapters 10 and 11. Chapter 12 and 13 discussed about adjunctive treatment modalities and novel therapeutic compounds in clinical trial and targets for future drug development. This book provides complete information about current landscape for multiple myeloma which is helpful in future aspects.
Multiple Myeloma And Other Plasma Cell Disorders
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Author : Bhratri BHUSHAN
language : en
Publisher:
Release Date : 2019-05-22
Multiple Myeloma And Other Plasma Cell Disorders written by Bhratri BHUSHAN and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-22 with categories.
Multiple myeloma accounts for 1 to 2 percent of all human cancers and around 15 percent of all hematologic malignancies. The premalignant condition leading to this disorder, monoclonal gammopathy of undetermined significance is found in 3 percent of the population above 50 years of age and progresses to multiple myeloma and other dyscrasias of plasma cells at a rate of 1 percent per year. So, not only the incidence and prevalence of these disorders is high, the science of management of myeloma and other plasma cell dyscrasias has become exceedingly complex with incorporation of genetic studies in the mainstream diagnostic and treatment decision making algorithms; as well as refinement of response assessment criteria, not to mention the bewildering array of treatment choices available, new therapies continually being added to the armamentarium and paradigm shift in established practices like hematopoietic stem cell transplantation. This book encompasses the topics of multiple myeloma, monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, plasma cell leukemia, mixed cryoglobulinemia syndrome, the heavy chain diseases, POEMS syndrome and amyloidosis and aims at updating and refreshing the knowledge of medical professionals as well as an easy read for non-professionals, to familiarize themselves with the concepts of plasma cell dyscrasias and thus empowering informed decision making.
The Saint Chopra Guide To Inpatient Medicine
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Author : Sanjay Saint
language : en
Publisher: Oxford University Press, USA
Release Date : 2018
The Saint Chopra Guide To Inpatient Medicine written by Sanjay Saint and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
Preceded by: Clinical clerkship in inpatient medicine / Sanjay Saint. 3rd ed. c2010.
Polyneuropathies Associated With Plasma Cell Dyscrasias
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Author : John J. Kelly
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Polyneuropathies Associated With Plasma Cell Dyscrasias written by John J. Kelly and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Plasma cell dyscrasias are common causes of peripheral neuropathy. Peri pheral neuropathy may be the first manifestation of multiple myeloma, amyloidosis, or monoclonal gammopathy of undetermined significance (MGUS). Peripheral neuropathy occurs in more than one-half of patients with osteosclerotic myeloma. The hematologic disorders are such an important association with peripheral polyneuropathy that, for the last decade, we have obtained a metastatic bone survey and immunoelectrophoresis of serum and a 24-hour urine specimen on all patients older than 40 years with undiagnosed peripheral neuropathy. This textbook on polyneuropathies and plasma cell dyscrasia is welcome, because the subject is of considerable medical importance and because the authors are expert in these disorders. Kelly's studies have shown that a systematic search for monoclonal proteins in plasma and urine among patients with neuropathy of unknown cause increases diagnostic yield. Latov's studies have focused on the role of myelin associated glycoproteins (MAG) in the induction of neuropathy. Kyle, director of the Special Protein Laboratory at Mayo Clinic, brings a broad clinical and laboratory perspective and experi ence. The timing of the textbook is just right, because there is much new information which needs to be summarized.
Pathology Of Bone And Joint Disorders Print And Online Bundle
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Author : Edward F. McCarthy
language : en
Publisher: Cambridge University Press
Release Date : 2014-11-20
Pathology Of Bone And Joint Disorders Print And Online Bundle written by Edward F. McCarthy and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-20 with Medical categories.
Fully updated new edition covering all aspects of bone and joint diseases in one easily readable volume. Color illustrations throughout.