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Multiple Sclerosis And Related Disorders


Multiple Sclerosis And Related Disorders
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Clinical Neuroimmunology


Clinical Neuroimmunology
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Author : Syed A. Rizvi
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-03

Clinical Neuroimmunology written by Syed A. Rizvi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-03 with Medical categories.


Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders serves as an indispensable resource for physicians interested in, and dealing with, this very complex and evolving branch of neurology. This comprehensive title provides an introduction to basic neuroimmunology and principles of immunotherapy and also serves as a thorough guide to immune-mediated disorders of the central and peripheral nervous system, as well as other systemic disorders with a significant neuroimmunologic component. The chapters are written by experts in their fields and include the most up to date scientific information. This volume is made to simplify complex immunological mechanisms and to focus on practical patient-related issues. Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders is an invaluable addition to the literature and will be of significant interest to neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases.



Multiple Sclerosis And Related Disorders


Multiple Sclerosis And Related Disorders
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Author : Douglas S. Goodin
language : en
Publisher: Elsevier
Release Date : 2014-02-05

Multiple Sclerosis And Related Disorders written by Douglas S. Goodin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-05 with Medical categories.


Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. - A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis - Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options - Each chapter is translational and focuses on current research and impact on diagnosis and treatment options



Multiple Sclerosis And Related Disorders


Multiple Sclerosis And Related Disorders
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Author : Robert Fox
language : en
Publisher: Springer Publishing Company
Release Date : 2018-08-28

Multiple Sclerosis And Related Disorders written by Robert Fox and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-28 with Medical categories.


Revised and updated second edition of Multiple Sclerosis and Related Disorders: Clinical Guide to Diagnosis, Medical Management, and Rehabilitation, the only comprehensive but practical source of core information on multiple sclerosis and other demyelinating disorders. Intended as a ready reference for clinicians who provide ongoing care to MS patients, this book combines evidence-based science with experience-based guidance to present current standards and management protocols from leading MS centers. Beginning with the scientific underpinnings of MS for clinicians, the book proceeds through diagnosis, including initial symptoms, diagnostic criteria and classification, imaging, and differential diagnosis, and onto approved treatments for the various MS types and emerging therapies. Later parts of the book discuss symptom management and rehabilitation with chapters focusing on specific side effects, along with considerations for special populations, comorbidities, societal and family issues, and related autoimmune disorders that are often mistaken for MS. Throughout, chapters include lists of Key Points both for clinicians and for patients and families, and management pearls are boxed for quick reference and clinical utility. Illustrations, tables, algorithms, assessment scales, and up-to-date MRI imaging enrich the text, making this a wide-ranging clinical reference for all members of the MS care team. New to the Second Edition: Includes summary recommendations from new AAN practice guidelines for use of DMTs All chapters updated to reflect the latest literature and diagnostic criteria Five entirely new chapters added to expand coverage of treatment, rehabilitation and symptom management, and special issues related to MS Treatment section has been completely revised to better capture current approaches to disease modifying therapies, with separate chapters devoted to injection and oral therapies, infusion therapies, and treatments for progressive forms of MS Related autoimmune diseases section significantly expanded to include transverse myelitis, autoimmune encephalitis, and neurosarcoidosis



Multiple Sclerosis And Related Disorders


Multiple Sclerosis And Related Disorders
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Author : Alexander D. Rae-Grant
language : en
Publisher: Demos Medical Publishing
Release Date : 2013-06-18

Multiple Sclerosis And Related Disorders written by Alexander D. Rae-Grant and has been published by Demos Medical Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-18 with Health & Fitness categories.


Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders. In addition to thoroughly reviewing the newest disease-modifying treatments, the authors have devoted significant focus to the symptoms that frequently manifest and their treatment options. Symptoms and functional limitations are the Ïface of the diseaseÓ for patients, and present their own set of challenges for practitioners. The book proceeds through diagnosis (initial symptoms, criteria and classification, imaging, lab tests, and differential diagnosis), approved treatments for the various MS types including emerging therapies where appropriate, symptom management, rehabilitative issues, general health and wellness, and an overview of MS clinical trials. Special populations, societal and family issues, and related disorders that are often mistaken for MS are also covered. Dedicated chapters on neuromyelitis optica and acute disseminated encephalomyelitis incorporate newer diagnostic criteria. Because comorbidities often make the management of MS-related disability more complex, the book addresses these comorbidities as part of a comprehensive management plan. To enhance the clinical utility, critical-to-know information and management pearls are boxed for quick reference and most chapters include lists of ÏKey PointsÓ for clinicians, and for patients and families. Illustrations, tables, graphs, assessment scales, and up-to-date MRI imaging inform the text throughout. The treatment chapters include specific recommendations where available and highlight areas of controversy. Illustrative cases go beyond the literature to amplify clinical recommendations and provide real-world guidance for practitioners. Illustrations, tables, graphs, assessment scales, and up-to-date MRI imaging inform the text throughout. Multiple Sclerosis and Related Disorders features: Comprehensive clinical reference for all members of the MS care team Focus on practical approaches to diagnosis, treatment, counseling, and rehabilitative strategies Reviews the latest disease modifying therapies Extensive chapters on symptom management and womenÌs issues in MS Edited and written primarily by expert clinicians at Cleveland Clinic/Mellen Center Evidence- and experience-based guidance Dedicated chapters on neuromyelitis optica and acute disseminated encephalomyelitis incorporating newer diagnostic criteria Includes treatment guidelines and numerous illustrations, tables, scales key information is highlighted for quick reference



White Matter Diseases


White Matter Diseases
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Author : Massimo Filippi
language : en
Publisher: Springer Nature
Release Date : 2020-02-13

White Matter Diseases written by Massimo Filippi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-13 with Medical categories.


This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment.



Multiple Sclerosis And Related Disorders Challenges And Approaches To Mechanisms Biomarkers And Therapeutic Targets


Multiple Sclerosis And Related Disorders Challenges And Approaches To Mechanisms Biomarkers And Therapeutic Targets
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Author : Jinzhou Feng
language : en
Publisher: Frontiers Media SA
Release Date : 2024-05-28

Multiple Sclerosis And Related Disorders Challenges And Approaches To Mechanisms Biomarkers And Therapeutic Targets written by Jinzhou Feng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-28 with Medical categories.


Multiple sclerosis (MS) is an autoimmune condition that causes inflammatory damage to the central nervous system. The pathologic features are diffuse and focal inflammation, demyelination, gliosis, and neuronal damage in the optic nerves, brain, and spinal cord. Multiple sclerosis remains a challenging and disabling disease. There is a greater understanding of the underlying genetic and environmental factors driving the disorder, including low vitamin D levels, smoking, and obesity. Early and accurate diagnosis is essential and needs to be supported by diagnostic criteria, including imaging and spinal fluid abnormalities in patients with clinically isolated syndromes. Other demyelinating diseases are neuromyelitis optica spectrum disorders (NMOSD), anti-myelin oligodendrocyte glycoprotein antibody disease (MOGAD), and acute disseminated encephalomyelitis (ADEM).



Multiple Sclerosis And Associated Demyelinating Disorders An Issue Of Neuroimaging Clinics Of North America E Book


Multiple Sclerosis And Associated Demyelinating Disorders An Issue Of Neuroimaging Clinics Of North America E Book
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Author : Frederik Barkhof
language : en
Publisher: Elsevier Health Sciences
Release Date : 2024-07-01

Multiple Sclerosis And Associated Demyelinating Disorders An Issue Of Neuroimaging Clinics Of North America E Book written by Frederik Barkhof and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-01 with Science categories.


In this issue of Neuroimaging Clinics, guest editors Drs. Frederik Barkhof and Yaou Liu bring their considerable expertise to the topic of Multiple Sclerosis and Associated Demyelinating Disorders. Top experts in the field discuss advanced brain imaging in CNS demyelinating diseases; new imaging markers in MS and related disorders: smoldering inflammation and central vein sign; the use of AI in MS and white matter disease; optic nerve imaging in MS and related disorders; atypical demyelinating disorders; and more. Co-Editor Frederik Barkhof, MD, has received the National Multiple Sclerosis Society and the American Academy of Neurology's 2018 John Dystel Prize for Multiple Sclerosis Research for his many years of outstanding research in the field of MS, especially in advancing the understanding and clinical use of brain imaging. - Contains 12 relevant, practice-oriented topics including diagnostic criteria for MS, NMOSD and MOGAD; routine MRI protocol and standardization in CNS demyelinating diseases; spinal cord imaging in MS and related disorders; treatment monitoring in MS: efficacy and safety; cognitive impairment in MS and related disorders; and more. - Provides in-depth clinical reviews on multiple sclerosis and associated demyelinating disorders, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.



Multiple Sclerosis As A Neuronal Disease


Multiple Sclerosis As A Neuronal Disease
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Author : Stephen Waxman
language : en
Publisher: Elsevier
Release Date : 2005-05-27

Multiple Sclerosis As A Neuronal Disease written by Stephen Waxman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-27 with Medical categories.


This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neurons as a result of MS. It places MS in a new and important perspective that not only explains the basis for symptom production, remission, and progress in MS, but also promises to open up new therapeutic possibilities.* Brings together the latest information from clinical, pathological, imaging, molecular, and pharmacological realms to explore the neurobiology of Multiple Sclerosis* Places MS in a new and important perspective that promises to open up new therapeutic avenues* Superbly illustrated and referenced



Neuroimmunology


Neuroimmunology
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Author : Amanda L. Piquet
language : en
Publisher: Springer Nature
Release Date : 2021-03-08

Neuroimmunology written by Amanda L. Piquet and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-08 with Medical categories.


This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentations in neuroimmunology, including pediatric demyelinating diseases. These sections provide practical clinical information to improve the reader’s knowledge in this complex field. The chapters are written by world renown authors with extensive knowledge to help provide up to date information. The full scope of autoimmune neurology is discussed, which is a unique feature of this book. Neuroimmunology serves as a resource for those in training including residents and fellows to provide clear clinical reasoning and background in a rapidly advancing field.



Neurourology


Neurourology
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Author : Limin Liao
language : en
Publisher: Springer
Release Date : 2019-04-18

Neurourology written by Limin Liao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-18 with Medical categories.


This book introduce neurourology as an emerging interdisciplinary area that covers the basic and clinical studies of the neural control on the normal lower urinary tract and the lower/upper urinary tract dysfunction due to neuropathy disorders. It systematically describes all aspects of neurourology from the epidemiology of the neurogenic bladder; to the pathology and pathophysiology of the lower urinary tract; to the diagnosis and treatment of the neurogenic bladder by conservative therapies or surgeries. This book provides a useful resource for medical doctors, nurses and students in the field of neurourological conditions. All the topics are written by internationally recognized specialists in their field.