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Multiscale Mechanobiology In Tissue Engineering


Multiscale Mechanobiology In Tissue Engineering
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Multiscale Mechanobiology In Tissue Engineering


Multiscale Mechanobiology In Tissue Engineering
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Author : Damien Lacroix
language : en
Publisher: Springer
Release Date : 2018-07-31

Multiscale Mechanobiology In Tissue Engineering written by Damien Lacroix and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-31 with Science categories.


This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.



Multi Scale Extracellular Matrix Mechanics And Mechanobiology


Multi Scale Extracellular Matrix Mechanics And Mechanobiology
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Author : Yanhang Zhang
language : en
Publisher:
Release Date : 2020

Multi Scale Extracellular Matrix Mechanics And Mechanobiology written by Yanhang Zhang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Biomedical engineering categories.


This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.



Multiscale Modeling In Biomechanics And Mechanobiology


Multiscale Modeling In Biomechanics And Mechanobiology
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Author : Suvranu De
language : en
Publisher: Springer
Release Date : 2014-10-10

Multiscale Modeling In Biomechanics And Mechanobiology written by Suvranu De and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Technology & Engineering categories.


Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.



Multiscale Mechanobiology Of Bone Remodeling And Adaptation


Multiscale Mechanobiology Of Bone Remodeling And Adaptation
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Author : Peter Pivonka
language : en
Publisher: Springer
Release Date : 2017-06-20

Multiscale Mechanobiology Of Bone Remodeling And Adaptation written by Peter Pivonka and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-20 with Science categories.


The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.



Mechanobiology In Health And Disease


Mechanobiology In Health And Disease
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Author : Stefaan Verbruggen
language : en
Publisher: Academic Press
Release Date : 2018-08-09

Mechanobiology In Health And Disease written by Stefaan Verbruggen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-09 with Medical categories.


Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. - Provides an essential digest of primary research from many fields and disciplines in one convenient volume - Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives - Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science



Advances In Heart Valve Biomechanics


Advances In Heart Valve Biomechanics
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Author : Michael S. Sacks
language : en
Publisher: Springer
Release Date : 2019-04-08

Advances In Heart Valve Biomechanics written by Michael S. Sacks and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-08 with Science categories.


This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.



Advances In Biomedical Engineering Research And Application 2012 Edition


Advances In Biomedical Engineering Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26

Advances In Biomedical Engineering Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Technology & Engineering categories.


Advances in Biomedical Engineering Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biomedical Engineering. The editors have built Advances in Biomedical Engineering Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biomedical Engineering in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biomedical Engineering Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Multi Scale Extracellular Matrix Mechanics And Mechanobiology


Multi Scale Extracellular Matrix Mechanics And Mechanobiology
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Author : Yanhang Zhang
language : en
Publisher: Springer
Release Date : 2019-07-12

Multi Scale Extracellular Matrix Mechanics And Mechanobiology written by Yanhang Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-12 with Technology & Engineering categories.


This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.



Skin Biophysics


Skin Biophysics
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Author : Georges Limbert
language : en
Publisher: Springer
Release Date : 2019-05-28

Skin Biophysics written by Georges Limbert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-28 with Technology & Engineering categories.


This book presents state-of-the-art experimental and modelling techniques for skin biophysics that are currently used in academic and industrial research. It also identifies current and future challenges, as well as a growing number of opportunities in this exciting research field. The book covers the basics of skin physiology, biology, microstructural and material properties, and progressively introduces the reader to established experimental characterisation protocols and modelling approaches. Advanced topics in modelling theories and numerical implementation are also presented. The book focusses especially on: 1. Basic physiology, molecular biology, microstructural and material properties of the skin. 2. Experimental characterisation techniques for the skin (including imaging): in vivo and in vitro techniques and combination of those with in silico approaches. 3. State-of-the-art constitutive models of the skin: elastic, anelastic and mechanobiological formulations (e.g. growth, ageing, healing). 4. Applications: mechanics, damage, biological growth, healing, ageing and skin tribology. This book is addressed to postgraduate students in biomedical/mechanical/civil engineering, (bio)physics and applied mathematics, postdoctoral researchers, as well as scientists and engineers working in academia and industry engaged in skin research, particularly, if at the cross-roads of physical experiments, imaging and modelling. The book is also be of interest to clinicians/biologists who wish to learn about the possibilities offered by modern engineering techniques for skin science research and, by so doing, provide them with an incentive to broaden their outlook, engage more widely with the non-clinical research communities and, ultimately, help cross-fertilising new ideas that will lead to better treatment plans and engineering solutions.



Biomechanics And Functional Tissue Engineering


Biomechanics And Functional Tissue Engineering
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Author : Ziyad S. Haidar
language : en
Publisher:
Release Date : 2021

Biomechanics And Functional Tissue Engineering written by Ziyad S. Haidar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Tissue engineering categories.


Biomechanics and Functional Tissue Engineering is a useful resource for scientists, researchers, engineers, and clinical practitioners involved in bioengineering solutions for improved patient quality of life. It focuses on the potentially impactful role of applied and functional bio-dental tissue engineering, drug/gene delivery (controlled and metered systems) and cell therapy, bioscaffolds, image-guided and image-assisted surgery, nanodentistry, and biomechanics towards developing better solutions for problems and conditions of the orodental and cranio-maxillofacial complex and beyond.