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Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation


Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation
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Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation


Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation
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Author : Jerome Noailly
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-11

Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation written by Jerome Noailly and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-11 with Science categories.




Multiscale Cancer Modeling


Multiscale Cancer Modeling
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Author : Thomas S. Deisboeck
language : en
Publisher: CRC Press
Release Date : 2010-12-08

Multiscale Cancer Modeling written by Thomas S. Deisboeck and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-08 with Mathematics categories.


Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat



Charney And Nestler S Neurobiology Of Mental Illness


Charney And Nestler S Neurobiology Of Mental Illness
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Author : Dennis Charney
language : en
Publisher: Oxford University Press
Release Date : 2025-01-03

Charney And Nestler S Neurobiology Of Mental Illness written by Dennis Charney and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-03 with Education categories.


"The genetic investigation into mental illnesses has progressed rapidly since the mapping of the human genome. Driven by advances in genomic profiling technology, massive genomic datasets are powering the discovery of genetic variation associated to complex traits including mental illness. From severe neurodevelopmental disorders to schizophrenia and depression, genetic variation plays some role in risk. Critically, most mental illnesses are complex, multifactorial and the consequence of a combination of genetic and environmental influences. This chapter will introduce the genome, its variation, and the methods used to identify what variants and genes matter for mental illnesses"--



Advances In Ceramic Biomaterials


Advances In Ceramic Biomaterials
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Author : Paola Palmero
language : en
Publisher: Woodhead Publishing
Release Date : 2017-09-15

Advances In Ceramic Biomaterials written by Paola Palmero and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-15 with Technology & Engineering categories.


Bioceramics are an important class of biomaterials. Due to their desirable attributes such as biocompatibility and osseointegration, as well as their similarity in structure to bone and teeth, ceramic biomaterials have been successfully used in hard tissue applications. In this book, a team of materials research scientists, engineers, and clinicians bridge the gap between materials science and clinical commercialization providing integrated coverage of bioceramics, their applications and challenges. The book is divided into three parts. The first part is a review of classes of medical-grade ceramic materials, their synthesis and processing as well as methods of property assessment. The second part contains a review of ceramic medical products and devices developed, their evolution, their clinical applications and some of the lessons learned from decades of clinical use. The third part outlines the challenges to improve performance and the directions that novel approaches and advanced technologies are taking, to meet these challenges. With a focus on the dialogue between surgeons, engineers, material scientists, and biologists, this book is a valuable resource for researchers and engineers working toward long-lasting, reliable, customized biomedical ceramic and composites devices. - Edited by a team of experts with expertise in industry and academia - Compiles the most relevant aspects on regulatory issues, standards and engineering of bioceramic medical devices as inspired by commercial and clinical needs - Introduces bioceramics, their evolution and applications in hard tissue engineering and medical devices



Skeletal Muscle Repair And Regeneration


Skeletal Muscle Repair And Regeneration
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Author : Stefano Schiaffino
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-01-18

Skeletal Muscle Repair And Regeneration written by Stefano Schiaffino and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-18 with Medical categories.


Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. It provides up-to-date coverage and presents a broad range of topics.



Cardiovascular Solid Mechanics


Cardiovascular Solid Mechanics
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Author : Jay D. Humphrey
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Cardiovascular Solid Mechanics written by Jay D. Humphrey and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.


The vitality of the cardiovascular system, which consists of the heart, vas culature, and blood, depends on its response to a host of complex stimuli, including biological, chemical, electrical, mechanical, and thermal. The focus of this book, however, is on the response of the heart and arteries to mechanical loads from the perspective of nonlinear solid mechanics. Through my own research in this field, I have come to realize that study ing the complex responses of cardiovascular cells, tissues, and organs nec essarily requires a combined theoretical, experimental, and computational approach. Theory is needed to guide the performance and interpretation of experiments as well as to synthesize the results; experiment is needed to study the responses of the system to well-controlled loads and to test can didate hypotheses and theories; and due to the geometric and material non linearities inherent to cardiovascular mechanics, computation is needed to analyze data as well as to solve boundary and initial value problems that correspond to either experimental or in vivo conditions. One of the primary goals of this book is to introduce together basic analytical, experimental, and computational methods and to illustrate how these methods can and must be integrated to gain a more complete understanding of the bio mechanics of the heart and vasculature. Despite the focus on cardiovascu lar mechanics, the fundamental methods, indeed many of the specific results, are generally applicable to many different soft tissues.



Composition And Function Of The Extracellular Matrix In The Human Body


Composition And Function Of The Extracellular Matrix In The Human Body
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Author : Francesco Travascio
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-06-15

Composition And Function Of The Extracellular Matrix In The Human Body written by Francesco Travascio and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-15 with Science categories.


The extracellular matrix (ECM) is an ensemble of non-cellular components present within all tissues and organs of the human body. The ECM provides structural support for scaffolding cellular constituents and biochemical and biomechanical support for those events leading to tissue morphogenesis, differentiation and homeostasis. Essential components of all ECMs are water, proteins and polysaccharides. However, their composition, architecture and bioactivity greatly vary from tissue to tissue in relation to the specific role the ECM is required to assume. This book overviews the role of the ECM in different tissues and organs of the human body.



Feedback Systems


Feedback Systems
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Author : Karl Johan Åström
language : en
Publisher: Princeton University Press
Release Date : 2021-02-02

Feedback Systems written by Karl Johan Åström and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-02 with Technology & Engineering categories.


The essential introduction to the principles and applications of feedback systems—now fully revised and expanded This textbook covers the mathematics needed to model, analyze, and design feedback systems. Now more user-friendly than ever, this revised and expanded edition of Feedback Systems is a one-volume resource for students and researchers in mathematics and engineering. It has applications across a range of disciplines that utilize feedback in physical, biological, information, and economic systems. Karl Åström and Richard Murray use techniques from physics, computer science, and operations research to introduce control-oriented modeling. They begin with state space tools for analysis and design, including stability of solutions, Lyapunov functions, reachability, state feedback observability, and estimators. The matrix exponential plays a central role in the analysis of linear control systems, allowing a concise development of many of the key concepts for this class of models. Åström and Murray then develop and explain tools in the frequency domain, including transfer functions, Nyquist analysis, PID control, frequency domain design, and robustness. Features a new chapter on design principles and tools, illustrating the types of problems that can be solved using feedback Includes a new chapter on fundamental limits and new material on the Routh-Hurwitz criterion and root locus plots Provides exercises at the end of every chapter Comes with an electronic solutions manual An ideal textbook for undergraduate and graduate students Indispensable for researchers seeking a self-contained resource on control theory



Fractional Calculus In Bioengineering


Fractional Calculus In Bioengineering
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Author : Richard L. Magin
language : en
Publisher:
Release Date : 2006-01-01

Fractional Calculus In Bioengineering written by Richard L. Magin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Biomedical engineering categories.