Multiscale Cancer Modeling
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Multiscale Cancer Modeling
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Author : Thomas S. Deisboeck
language : en
Publisher: CRC Press
Release Date : 2010-12-08
Multiscale Cancer Modeling written by Thomas S. Deisboeck and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-08 with Mathematics categories.
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
Cell Mechanics
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Author : Arnaud Chauviere
language : en
Publisher: CRC Press
Release Date : 2010-01-27
Cell Mechanics written by Arnaud Chauviere and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-27 with Mathematics categories.
Ubiquitous and fundamental in cell mechanics, multiscale problems can arise in the growth of tumors, embryogenesis, tissue engineering, and more. Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling brings together new insight and research on mechanical, mathematical, physical, and biological approaches for simulating the behavior
Cellular Potts Models
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Author : Marco Scianna
language : en
Publisher: CRC Press
Release Date : 2013-03-26
Cellular Potts Models written by Marco Scianna and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-26 with Mathematics categories.
This work shows how the cellular Potts model can be used as a framework for model building and how extended models can achieve even better biological practicality, accuracy, and predictive power. It focuses on ways to integrate and interface the basic cellular Potts model at the mesoscopic scale with approaches that accurately model microscopic dynamics. These extensions are designed to create a nested and hybrid environment, where the evolution of a biological system is realistically driven by the constant interplay and flux of information between the different levels of description.
Cancer Modelling And Simulation
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Author : Luigi Preziosi
language : en
Publisher: CRC Press
Release Date : 2003-06-18
Cancer Modelling And Simulation written by Luigi Preziosi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-18 with Mathematics categories.
Understanding how cancer tumours develop and spread is vital for finding treatments and cures. Cancer Modelling and Simulation demonstrates how mathematical modelling and computer simulation techniques are used to discover and gain insight into the dynamics of tumour development and growth. It highlights the benefits of tumour modelling, such as discovering optimal tumour therapy schedules, identifying the most promising candidates for further clinical investigation, and reducing the number of animal experiments. By examining the analytical, mathematical, and biological aspects of tumour growth and modelling, the book provides a common language and knowledge for professionals in several disciplines.
Multiscale Modelling In Biomedical Engineering
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Author : Dimitrios I. Fotiadis
language : en
Publisher: John Wiley & Sons
Release Date : 2023-05-31
Multiscale Modelling In Biomedical Engineering written by Dimitrios I. Fotiadis and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-31 with Science categories.
Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the molecular to the cellular, tissue, and organ level. It then examines multiscale modeling applications in specific functional areas, like mechanotransduction, musculoskeletal, and cardiovascular systems. Multiscale Modelling in Biomedical Engineering offers readers experiments and exercises to illustrate and implement the concepts contained within. Readers will also benefit from the inclusion of: A thorough introduction to systems biology and multi-scale modeling, including a survey of various multi-scale methods and approaches and analyses of their application in systems biology Comprehensive explorations of biomedical imaging and nanoscale modeling at the molecular, cell, tissue, and organ levels Practical discussions of the mechanotransduction perspective, including recent progress and likely future challenges In-depth examinations of risk prediction in patients using big data analytics and data mining Perfect for undergraduate and graduate students of bioengineering, biomechanics, biomedical engineering, and medicine, Multiscale Modelling in Biomedical Engineering will also earn a place in the libraries of industry professional and researchers seeking a one-stop reference to the basic engineering principles of biological systems.
Modelling And Computational Approaches For Multi Scale Phenomena In Cancer Research From Cancer Evolution To Cancer Treatment
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Author : Raluca Eftimie
language : en
Publisher: World Scientific
Release Date : 2024-11-12
Modelling And Computational Approaches For Multi Scale Phenomena In Cancer Research From Cancer Evolution To Cancer Treatment written by Raluca Eftimie and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-12 with Mathematics categories.
Cancer development and progression is the result of biological phenomena that occur across multiple temporal and spatial scales. Recent years have seen a flurry of multi-scale mathematical models developed to generate and test new biological hypotheses related to cancer development, progression, and various treatment approaches. This has led to the development of new computational and analytical approaches aimed at investigating these multi-scale models.This review volume summarises the state of the art related to the modelling, experimental investigation, and data assimilation of multi-scale phenomena during cancer development, evolution, and treatment, as well as the computational and analytical investigation of the multi-scale models developed to reproduce the biological phenomena. The book also identifies the experimental and theoretical open problems that will have to be addressed in the near future in order to advance this field. Modelling and Computational Approaches for Multi-Scale Phenomena in Cancer Research is an excellent resource for both early career and advanced researchers.
Stochastic Models Of Tumor Latency And Their Biostatistical Applications
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Author : Andrej Yu Yakovlev
language : en
Publisher: World Scientific
Release Date : 1996
Stochastic Models Of Tumor Latency And Their Biostatistical Applications written by Andrej Yu Yakovlev and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
This research monograph discusses newly developed mathematical models and methods that provide biologically meaningful inferences from data on cancer latency produced by follow-up and discrete surveillance studies. Methods for designing optimal strategies of cancer surveillance are systematically presented for the first time in this book. It offers new approaches to the stochastic description of tumor latency, employs biologically-based models for making statistical inference from data on tumor recurrence and also discusses methods of statistical analysis of data resulting from discrete surveillance strategies. It also offers insight into the role of prognostic factors based on the interpretation of their effects in terms of parameters endowed with biological meaning, as well as methods for designing optimal schedules of cancer screening and surveillance. Last but not least, it discusses survival models allowing for cure rates and the choice of optimal treatment based on covariate information, and presents numerous examples of real data analysis.
Multiscale Computer Modeling In Biomechanics And Biomedical Engineering
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Author : Amit Gefen
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-07-08
Multiscale Computer Modeling In Biomechanics And Biomedical Engineering written by Amit Gefen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Technology & Engineering categories.
This book reviews the state-of-the-art in multiscale computer modeling, in terms of both accomplishments and challenges. The information in the book is particularly useful for biomedical engineers, medical physicists and researchers in systems biology, mathematical biology, micro-biomechanics and biomaterials who are interested in how to bridge between traditional biomedical engineering work at the organ and tissue scales, and the newer arenas of cellular and molecular bioengineering.
Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation
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Author : Jerome Noailly
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-11
Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation written by Jerome Noailly and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-11 with Science categories.
Multiscale Modeling Of Cancer
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Author : Vittorio Cristini
language : en
Publisher: Cambridge University Press
Release Date : 2010-09-09
Multiscale Modeling Of Cancer written by Vittorio Cristini and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-09 with Technology & Engineering categories.
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.