Muscarinic Receptor Subtypes In Airway Smooth Muscle

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Muscarinic Receptor Subtypes In Smooth Muscle

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Author : Richard M. Eglen
language : en
Publisher: CRC Press
Release Date : 2020-10-07

Muscarinic Receptor Subtypes In Smooth Muscle written by Richard M. Eglen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-07 with Medical categories.

This book explores several subtypes of muscarinic receptors that modulate smooth muscle activity. Main topics include a classification of muscarinic receptors, biochemical responses that occur in smooth muscle, the role of muscarinic receptors in the function of gastrointestinal and genitourinary smooth muscle, and prejunctional muscarinic receptors in smooth muscle. Discussions cover the current state of research and are intended to generate further research into the design of novel therapeutics for disorders of smooth muscle function.

Muscarinic Receptor Subtypes In Airway Smooth Muscle

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Author : Adriaan F. Roffel
language : en
Publisher:
Release Date : 1990

Muscarinic Receptor Subtypes In Airway Smooth Muscle written by Adriaan F. Roffel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with categories.

Muscarinic Receptor Subtypes In Airway Smooth Muscle

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Author : Adriaan Frans Roffel
language : nl
Publisher:
Release Date : 1990

Muscarinic Receptor Subtypes In Airway Smooth Muscle written by Adriaan Frans Roffel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with categories.

Muscarinic Receptors In Airways Diseases

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Author : Johan Zaagsma
language : en
Publisher: Springer
Release Date : 2013-03-08

Muscarinic Receptors In Airways Diseases written by Johan Zaagsma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.

What are the different muscarinic acetylcholine receptor subtypes and how are they distributed in the airways and molecular signalling mechanisms? What is their function in neurogenic and non-neurogenic control of the airways and in inflammatory mechanisms? How is their gene expression regulated? The great importance of muscarinic acetylcholine receptors for the pathophysiology and treatment of chronic inflammatory obstructive airways diseases calls for a comprehensive and integrated overview of the current knowledge to address such questions, to discuss the role of these receptor subtypes in diseases such as asthma and COPD, and to present novel perspectives on antimuscarinic drug development. The present book is the worthy result of this need. It points out innovative insights into the hitherto poorly understood role of postjunctional muscarinic M2 receptors in airway smooth muscle contraction and sheds some light on the novel concepts of antimuscarinic drug development, with special reference to the l

Airways Smooth Muscle Neurotransmitters Amines Lipid Mediators And Signal Transduction

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Author : David Raeburn
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06

Airways Smooth Muscle Neurotransmitters Amines Lipid Mediators And Signal Transduction written by David Raeburn and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Airway Smooth Muscle

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Author : Devendra K. Agrawal
language : en
Publisher: CRC Press
Release Date : 1990-10-24

Airway Smooth Muscle written by Devendra K. Agrawal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-10-24 with Medical categories.

Airway smooth muscle plays a dominant role in bronchial asthma, as well as a significant role in various pulmonary diseases, such as chronic bronchitis, cystic fibrosis and emphysema. Myogenic, neurogenic, and humoral factors control airway smooth-muscle tone. This text provides a state-of-the-art summary and critical discussion of airway smooth muscle from a multidisciplinary point of view. Topics discussed include morphology, biochemical regulation, mechanical and electrophysiological behavior and reflex control of smooth muscle; the epithelium-derived relaxing factor; and methods to measure smooth muscle function in vivo in humans and experimental animals, as well as in vitro in isolated airway tissues. Also discussed are calcium and potassium channels and receptors for adrenergic, cholinergic and histaminergic systems in modulating receptor-response coupling in airway smooth muscle. Airway Smooth Muscle: Modulation of Receptors and Response provides essential information for researchers, teachers, pulmonary specialists and allergists, and students interested in learning about airway smooth muscle.

Airways Smooth Muscle Peptide Receptors Ion Channels And Signal Transduction

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Author : David Raeburn
language : en
Publisher: Springer
Release Date : 2012-12-06

Airways Smooth Muscle Peptide Receptors Ion Channels And Signal Transduction written by David Raeburn and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Muscarinic Receptors In Airway Smooth Muscle

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Author :
language : en
Publisher:
Release Date : 2013

Muscarinic Receptors In Airway Smooth Muscle written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.

Airway Smooth Muscle In Health And Disease

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Author : R.F. Coburn
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Airway Smooth Muscle In Health And Disease written by R.F. Coburn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

I organized this book because there is a need to put together in book form recent advances in our knowledge of how airway smooth muscle:works in health and in disease. After a period when it seemed that progress was very slow, there has been in the past few years an incredibly rapid gathering of knowledge in this area. In particular, our understanding has improved regarding the cascades of events that follow the initial binding of agonist to plasma membrane receptors and that lead to the cross-bridge movements that determine contraction. This advance in our knowledge was stimulated by use of single-and whole-cell channel recordings of plasma membrane currents and by description of the l3-receptor-GTP-binding protein-adenylate cyclase-cAMP coupling system, which serves as a model for other coupling mechanisms. The discovery of the receptor-activated inositol phospholipid transduction system has greatly stimulated research and led to advances in our understanding of mechanisms involved in smooth muscle con traction. Major advances were also triggered by the development of indicators for measuring free cytosolic calcium concentration and starting the unraveling of 2 the events involved in Ca + -dependent activation of contractile proteins. Al though most of the studies that led to our current understanding of these areas were performed on nonairway smooth muscle, these studies usually add to our understanding of airway smooth muscle, and there is an enlarging body of data that have been obtained on airway smooth muscle.

Smooth Muscle Excitation

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Author : T. B. Bolton
language : en
Publisher:
Release Date : 1996

Smooth Muscle Excitation written by T. B. Bolton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.

This book is a compendium of the latest electrophysiological research on smooth muscles from an international collection of authors. It includes recent discoveries in calcium stores and their relationship to contraction and to electrical changes in the membrane. A major section of the book concentrates on calcium release mechanisms in the cell, their control, and the consequences of calcium release in the cell for membrane events. Smooth Muscle Excitation also covers the effects of chemicals released from adjacent cells. Key Features * State-of-the-art volume that represents a synopsis of all work currently being undertaken in this area throughout the world * Content covers both basic and clinical research * Provides a range of drug development studies * Presents contributions from many internationally recognized smooth muscle physiologists