Mutation Randomness And Evolution
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Mutation Randomness And Evolution
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Author : Arlin Stoltzfus
language : en
Publisher: Oxford University Press
Release Date : 2021-04-22
Mutation Randomness And Evolution written by Arlin Stoltzfus and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-22 with Science categories.
What does it mean to say that mutation is random? How does mutation influence evolution? Are mutations merely the raw material for selection to shape adaptations? The author draws on a detailed knowledge of mutational mechanisms to argue that the randomness doctrine is best understood, not as a fact-based conclusion, but as the premise of a neo-Darwinian research program focused on selection. The successes of this research program created a blind spot - in mathematical models and verbal theories of causation - that has stymied efforts to re-think the role of variation. However, recent theoretical and empirical work shows that mutational biases can and do influence the course of evolution, including adaptive evolution, through a first come, first served mechanism. This thought-provoking book cuts through the conceptual tangle at the intersection of mutation, randomness, and evolution, offering a fresh, far-reaching, and testable view of the role of variation as a dispositional evolutionary factor. The arguments will be accessible to philosophers and historians with a serious interest in evolution, as well as to researchers and advanced students of evolution focused on molecules, microbes, evo-devo, and population genetics.
Randomness In Evolution
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Author : John Tyler Bonner
language : en
Publisher: Princeton University Press
Release Date : 2013-03-21
Randomness In Evolution written by John Tyler Bonner and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-21 with Science categories.
The important role that randomness plays in evolutionary change John Tyler Bonner, one of our most distinguished and insightful biologists, here challenges a central tenet of evolutionary biology. In this concise, elegantly written book, he makes the bold and provocative claim that some biological diversity may be explained by something other than natural selection. With his customary wit and accessible style, Bonner makes an argument for the underappreciated role that randomness—or chance—plays in evolution. Due to the tremendous and enduring influence of Darwin's natural selection, the importance of randomness has been to some extent overshadowed. Bonner shows how the effects of randomness differ for organisms of different sizes, and how the smaller an organism is, the more likely it is that morphological differences will be random and selection may not be involved to any degree. He traces the increase in size and complexity of organisms over geological time, and looks at the varying significance of randomness at different size levels, from microorganisms to large mammals. Bonner also discusses how sexual cycles vary depending on size and complexity, and how the trend away from randomness in higher forms has even been reversed in some social organisms. Certain to provoke lively discussion, Randomness in Evolution is a book that may fundamentally change our understanding of evolution and the history of life.
The Random Somatic Mutation Is Not Quite Random
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Author : Florentin Smarandache
language : en
Publisher: Infinite Study
Release Date : 2023-01-01
The Random Somatic Mutation Is Not Quite Random written by Florentin Smarandache and has been published by Infinite Study this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-01 with Science categories.
This research note challenges the idea that Random Somatic Mutations are entirely random, highlighting their non-equiprobable nature and their influence on evolution, involution, or indeterminacy. It recalls the Neutrosophic Theory of Evolution, extending Darwin’s theory, and emphasizes the importance of distinguishing between different senses of ‘random mutation’ in evolutionary theory.
Population Genetics Molecular Evolution And The Neutral Theory
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Author : Motoo Kimura
language : en
Publisher: University of Chicago Press
Release Date : 1994
Population Genetics Molecular Evolution And The Neutral Theory written by Motoo Kimura and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Science categories.
One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
Genetics And Randomness
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Author : Anatoly Ruvinsky
language : en
Publisher: CRC Press
Release Date : 2009-07-28
Genetics And Randomness written by Anatoly Ruvinsky and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-28 with Science categories.
Analyzes Randomness in Major Genetic Processes and Events No matter how far science advances, the proportion of what is knowable to what is random will remain unchanged, and attempts to ignore this critical threshold are futile at best. With the revolutionary explosion in genetic information discovery, it is crucially important to recognize the underlying limitations of scientific prediction in genetics. Genetics and Randomness furthers the understanding of the role randomness plays in critical biological processes. The book also navigates the complex nature of genetic uncertainty from different points of view and at various levels of biological organization. Avoids Unnecessary Technical Details and Specific Terminology Exploring areas ranging from basic quantum mechanics and molecular genetics to modern evolutionary genetics and the philosophy of mathematics, this well-organized text discusses: Spontaneity of mutations and their relation to subatomic randomness Deep links between subatomic fluctuations and long-term macroscopic changes in living organisms The multitude of random events that occur during development Segregation, genetic drift, and natural selection Randomness and uncertainty are not occasional and regretful deviations from the "true" principles upon which life is built. Genetics and Randomness illustrates the ubiquitous nature of randomness as an integral feature of all essential processes, effectively embracing a probabilistic understanding of the phenomena of life.
Mutation And Evolution
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Author : Ronny C. Woodruff
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mutation And Evolution written by Ronny C. Woodruff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Although debated since the time of Darwin, the evolutionary role of mutation is still controversial. In over 40 chapters from leading authorities in mutation and evolutionary biology, this book takes a new look at both the theoretical and experimental measurement and significance of new mutation. Deleterious, nearly neutral, beneficial, and polygenic mutations are considered in their effects on fitness, life history traits, and the composition of the gene pool. Mutation is a phenomenon that draws attention from many different disciplines. Thus, the extensive reviews of the literature will be valuable both to established researchers and to those just beginning to study this field. Through up-to-date reviews, the authors provide an insightful overview of each topic and then share their newest ideas and explore controversial aspects of mutation and the evolutionary process. From topics like gonadal mosaicism and mutation clusters to adaptive mutagenesis, mutation in cell organelles, and the level and distribution of DNA molecular changes, the foundation is set for continuing the debate about the role of mutation, fitness, and adaptability. It is a debate that will have profound consequences for our understanding of evolution.
Chance In Evolution
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Author : Grant Ramsey
language : en
Publisher: University of Chicago Press
Release Date : 2016-10-25
Chance In Evolution written by Grant Ramsey and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-25 with Science categories.
This illuminating volume explores the effects of chance on evolution, covering diverse perspectives from scientists, philosophers, and historians. The evolution of species, from single-celled organisms to multicellular animals and plants, is the result of a long and highly chancy history. But how profoundly has chance shaped life on earth? And what, precisely, do we mean by chance? Bringing together biologists, philosophers of science, and historians of science, Chance in Evolution is the first book to untangle the far-reaching effects of chance, contingency, and randomness on the evolution of life. The book begins by placing chance in historical context, starting with the ancients and moving through Darwin to contemporary biology. It documents the shifts in our understanding of chance as Darwin’s theory of evolution developed into the modern synthesis, and how the acceptance of chance in Darwinian theory affected theological resistance to it. Other chapters discuss how chance relates to the concepts of genetic drift, mutation, and parallel evolution—as well as recent work in paleobiology and the experimental evolution of microbes. By engaging in collaboration across biology, history, philosophy, and theology, this book offers a comprehensive overview both of the history of chance in evolution and of our current understanding of the impact of chance on life.
The Edge Of Evolution
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Author : Michael J. Behe
language : en
Publisher: Simon and Schuster
Release Date : 2008-06-17
The Edge Of Evolution written by Michael J. Behe and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-17 with Religion categories.
The author of Darwin's Black Box draws on new findings in genetics to pose an argument for intelligent design that refutes Darwinian beliefs about evolution while offering alternative analyses of such factors as disease, random mutations, and the human struggle for survival. Reprint. 40,000 first printing.
Mutation Driven Evolution
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Author : Masatoshi Nei
language : en
Publisher: OUP Oxford
Release Date : 2013-05-02
Mutation Driven Evolution written by Masatoshi Nei and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-02 with Science categories.
The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in DNA such as nucleotide substitution, gene duplication/deletion, chromosomal change, and genome duplication. A brief history of the principal evolutionary theories (Darwinism, mutationism, neo-Darwinism, and neo-mutationism) that preceded the theory of mutation-driven evolution is also presented in the context of the last 150 years of research. However, the core of the book is concerned with recent studies of genomics and the molecular basis of phenotypic evolution, and their relevance to mutation-driven evolution. In contrast to neo-Darwinism, mutation-driven evolution is capable of explaining real examples of evolution such as the evolution of olfactory receptors, sex-determination in animals, and the general scheme of hybrid sterility. In this sense the theory proposed is more realistic than its predecessors, and gives a more logical explanation of various evolutionary events. Mutation-Driven Evolution is suitable for graduate level students as well as professional researchers (both empiricists and theoreticians) in the fields of molecular evolution and population genetics. It assumes that the readers are acquainted with basic knowledge of genetics and molecular biology.
Mutation Driven Evolution
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Author : Masatoshi Nei
language : en
Publisher: OUP Oxford
Release Date : 2013-05-02
Mutation Driven Evolution written by Masatoshi Nei and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-02 with Science categories.
The purpose of this book is to present a new theory of mutation-driven evolution, which is based on recent advances in genomics and evolutionary developmental biology. This theory asserts that the driving force of evolution is mutation and natural selection is of secondary importance.