Mutations In Man
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Mutations In Man
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Author : G. Obe
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mutations In Man written by G. Obe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This year we remember the 39th anniversary of the atomic bomb explo sions in Hiroshima and Nagasaki, which led to the exposure of thou sands of people to high doses of ionizing radiations. Nearly 18 years earlier, on the 15th of September, 1927, H. J. Muller presented his paper The Problem of Genic Modification at the Fifth International Congress of Genetics in Berlin, in which he brilliantly demonstrated the muta genic activity of X-rays. In 1928, K. H. Bauer formulated his mutation theory of the origin of cancer, and already in 1914, Th. Boveri speculat ed that tumor cells originate from an abnormal chromosomal comple ment. In the meantime we have learned that also nonionizing radiation and an immense number of environmental chemicals, both, man-made and naturally occurring, are mutagenic in a variety of test systems, in cluding human cells. In no case has it been shown unequivocally that physical or chemical mutagens have led to an elevation of the mutation rate in the germ cells of man, but in view of the huge body of experi mental data this seems to be a problem of detection. It can be expect ed that germ cell mutations are induced as a consequence of exposure to mutagens in man, as yet undetectable with the methods at hand. An uncontrolled addition of mutations to the human gene pool may well have unforeseen and catastrophic consequences in future genera tions for whom we should feel responsible.
Mutations In Man
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Author : G Obe (Ed)
language : en
Publisher:
Release Date : 1984
Mutations In Man written by G Obe (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.
Mutations In Man
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Author : G OBE
language : en
Publisher:
Release Date : 1984-03-01
Mutations In Man written by G OBE and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984-03-01 with categories.
Technologies For Detecting Heritable Mutations In Human Beings
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Author :
language : en
Publisher: DIANE Publishing
Release Date : 1986
Technologies For Detecting Heritable Mutations In Human Beings written by and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical genetics categories.
Crumbling Genome
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Author : Alexey S. Kondrashov
language : en
Publisher: John Wiley & Sons
Release Date : 2017-07-12
Crumbling Genome written by Alexey S. Kondrashov and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-12 with Science categories.
A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.
How Science Proves That The Theory Of Evolution Is Impossible Why Humans Can Never Evolve From Mutations Transpiring And How Humans Can Be Augmented By Becoming Cyborgs
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Author : Dr Harrison Sachs
language : en
Publisher:
Release Date : 2020-02-08
How Science Proves That The Theory Of Evolution Is Impossible Why Humans Can Never Evolve From Mutations Transpiring And How Humans Can Be Augmented By Becoming Cyborgs written by Dr Harrison Sachs and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-08 with categories.
This essay sheds light on how science proves that the theory of evolution is impossible and also elucidates why humans can never evolve from mutations transpiring. Moreover, how humans can be augmented by becoming cyborgs is delineated in this essay. In spite of what you were indoctrinated to believe, it is not only easier than anytime in history to utilize science to vindicate the existence of God, the quintessential, divine creator and master of the multiverse, but it is also easier to disprove the illogical theory of evolution. Human beings were created by God and are sheer and utter consciousness as multidimensional, spiritual beings who vicariously experience this simulated reality through their earthly avatars, receivers, vessels, or bodies as most people like to call them. Humans were created by God and have profusely devolved overtime from mutations transpiring. Mutations are always deleterious and are never beneficial to the human species. Mutations always cause you to lose genetic information and never gain genetic information. The theory of evolution makes the irrational contention that mutations are beneficial, when in fact the polar opposite is true. The occurrence of mutations is never salubrious, but rather is always deleterious. Mutations to the genes are always adverse changes which bastardizes the original genetic code. A human being's earthly vessel can never organically change it something outside the parameters of its DNA in this simulation. If the human genome can be thought of as a book then the occurrence of a mutation can always be thought of as outright ripping a chapter out of a book, hence bastardizing the original genetic code and devolving the earthly vessel of the being. Humans are a maladaptive species that can never possess the ability to physically evolve in this simulated reality, because unlike the fictitious Pokemon characters, human beings only have the anatomy to physically devolve into lesser humans beings if they succumb to genetic mutations. These genetic mutations cause humans beings to loose more and more of their original, sacrosanct genetic code and bastardizes their genomes. In other words, genetic mutations will always adversely impinge on your original genetic code in all facets and will devolve you as you loose more and more of your irreplaceable genetic code in this simulated reality. Nothing salubrious nor fruitful can ever ensue from mutations transpiring. Another fallacy of the theory of evolution, beyond mutation being falsely perceived as beneficial, is the groundless notion that something can come from nothing. The contention that something can come from nothing in a cause and effect simulated reality does not make any rational sense. There is a cause behind every effect and every effect can be traced back to a cause. If this fallacy of life emerging from nothing were the case then humans would be spawning out of nowhere. In spite of its sheer asininity, most people mistakenly believe that humans can come from nothing and are not their own separate species. The theory of evolution is a groundless theory that does not offer a modicum of scientific merit in any facet. Human beings have devolved overtime due to the deleterious occurrence of genetic mutations. Moreover, humans beings do not have the anatomy to ever physically evolve in this simulated reality, unlike the fictitious Pokemon characters. Humans are a maladaptive species that are perhaps preordained to further devolve overtime as they succumb to more and more adverse genetic mutations due to living insalubrious lives fraught with calamitous issues that eminently impinge on their health, happiness, and well-being. In other words, humans are not even livings salubrious lives and it would behoove humans to focus on living salubrious lives which are conducive to optimizing their health so that they can safeguard the structural integrity of their sacrosanct genetic code and mitigate risks for mutations transpiring.
Deleterious Mutations In Man
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Author : Newton Freire-Maia
language : en
Publisher:
Release Date : 1960
Deleterious Mutations In Man written by Newton Freire-Maia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1960 with Consanguinity categories.
Chemical Mutagens
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Author : Alexander Hollaender
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chemical Mutagens written by Alexander Hollaender and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The ready acceptance and wide demand for copies of the first two volumes of Chemical Mutagens: Principles and Methods Jar Their Detection have demon strated the need for wider dissemination of information on this timely and urgent subject. Therefore, it was imperative that a third volume be prepared to include more detailed discussions on techniques of some of the methods that were presented from a theoretical point of view in the first two volumes, and to update this rapidly expanding field with current findings and the new developments that have taken place in the past three years. Also included is a special chapter by Dr. Charlotte Auerbach giving the historical background of the discovery of chemical mutagenesis. Methods for recognizing mutagenic compounds in vitro are a necessary preliminary step toward arriving at satisfactory solutions for recognizing significant mutation rates in man, which must be done before our test tube methods of detection can be considered reliable. Two chapters in this volume make important contributions to this problem. Due to the increasing activity in efforts to perfect techniques for detecting chemical mutagens and their effects on man, it is planned to continue this series of volumes as necessary to keep abreast of current findings.
Chemical Mutagenesis In Mammals And Man
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Author : F Vogel (Ed)
language : en
Publisher:
Release Date : 1970
Chemical Mutagenesis In Mammals And Man written by F Vogel (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Science categories.
Health Effects Of Exposure To Low Levels Of Ionizing Radiation
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Author : National Research Council
language : en
Publisher: National Academies
Release Date : 1990-02-01
Health Effects Of Exposure To Low Levels Of Ionizing Radiation written by National Research Council and has been published by National Academies this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-02-01 with Science categories.
This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.