Nano And Microparticle Induced Cell Death Inflammation And Immune Responses
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Nano And Microparticle Induced Cell Death Inflammation And Immune Responses
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Author : Shrikant R. Mulay
language : en
Publisher: Frontiers Media SA
Release Date : 2019-07-19
Nano And Microparticle Induced Cell Death Inflammation And Immune Responses written by Shrikant R. Mulay and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-19 with categories.
Nano- and microparticles including crystals, synthetic biomaterials, misfolded proteins or environmental particulates are involved in a wide range of biological processes and diseases. They may present as intrinsic or environmental toxins but may also be applied intentionally, e.g. as immune adjuvants, drug carriers or ion exchangers. The discovery that a wide range of nano- and microparticles share the capacity to induce IL-1β secretion via activation of the NLRP3 inflammasome in dendritic cells and macrophages has led to the hypothesis that nano- and microparticles may contribute in a uniform mechanistic manner to different disease entities. Other molecular mechanisms triggered by a range nano- and microparticles have also recently been identified including (i) the induction of regulated necrosis; (ii) neutrophil extracellular trap (NET) formation and (iii) foreign body granuloma formation as a mechanism of persistent tissue inflammation and scarring. Research on the biology of nano- and microparticle handling is currently under intense investigation. The cell type-specific responses of nano- and microparticle exposure deserves careful attention as well as the related secondary responses to these particles that lead to tissue remodeling. The immune system is at the center of these processes in terms of particle clearance, particle-induced cell death and inflammation, thereby limiting particle-related inflammation and orchestrating wound healing responses. In this Research Topic, we welcomed the submission of Original Research, Review and Mini-Review articles that addressed the significance of the immune system in particle-induced cell death, inflammation and immune responses. These findings will help facilitate new approaches to the prevention and management of particle-related diseases.
Biomedical Nanomaterials
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Author : Rostyslav S. Stoika
language : en
Publisher: Springer Nature
Release Date : 2021-09-11
Biomedical Nanomaterials written by Rostyslav S. Stoika and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-11 with Technology & Engineering categories.
This book characterizes how to design and synthesize nanomaterials of an organic and mineral nature. The book also discusses the visualization of developed nanomaterials and their bio-applications, as well as describes the biomedical effects and environmental impact of nanomaterials. This is an ideal book for students studying biomedicine or the life sciences, as well as researchers and professionals in medicine, environmental protection, biotechnology, agriculture, and the food industry. More specifically, this book addresses the important nanomaterials and nanobiotechnologies that are used in those fields in biomedicine and life sciences.
Innate Immunity Platelets And Their Interaction With Other Cellular Elements In Host Defense And Disease Pathogenesis
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Author : Meganathan Kannan
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-08
Innate Immunity Platelets And Their Interaction With Other Cellular Elements In Host Defense And Disease Pathogenesis written by Meganathan Kannan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-08 with Medical categories.
Polymer Particles
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Author : Masayoshi Okubo
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-02-10
Polymer Particles written by Masayoshi Okubo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-02-10 with Technology & Engineering categories.
In this special volume on polymer particles, recent trends and developments in the synthesis of nano- to micron-sized polymer particles by radical polymerization (Emulsion, Miniemulsion, Microemulsion, and Dispersion Polymerizations) of vinyl monomers in environmentally friendly heterogeneous aqueous and supercritical carbon dioxide fluid media are reviewed by prominent worldwide researchers. In addition to the important challenges and possibilities with regards to design and preparation of functionalized polymer particles of controlled size, the topics described are of great current interest due to the increased awareness of environmental issues.
Micro And Nanotechnology In Vaccine Development
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Author : Mariusz Skwarczynski
language : en
Publisher: William Andrew
Release Date : 2016-09-20
Micro And Nanotechnology In Vaccine Development written by Mariusz Skwarczynski and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-20 with Medical categories.
This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines
Biomedical Nanomaterials
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Author : Rostyslav S. Stoika
language : en
Publisher: Springer
Release Date : 2022-09-13
Biomedical Nanomaterials written by Rostyslav S. Stoika and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-13 with Technology & Engineering categories.
This book characterizes how to design and synthesize nanomaterials of an organic and mineral nature. The book also discusses the visualization of developed nanomaterials and their bio-applications, as well as describes the biomedical effects and environmental impact of nanomaterials. This is an ideal book for students studying biomedicine or the life sciences, as well as researchers and professionals in medicine, environmental protection, biotechnology, agriculture, and the food industry. More specifically, this book addresses the important nanomaterials and nanobiotechnologies that are used in those fields in biomedicine and life sciences.
Nanomaterials
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Author : Marcelo Larramendy
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-07-15
Nanomaterials written by Marcelo Larramendy and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-15 with Science categories.
This edited book, Nanomaterials - Toxicity and Risk Assessment, is a collection of current research and information on numerous advances on the toxicity and hazardous effects of nanomaterials, including theoretical and experimental approaches as well as nanotechnology applications in the field of medicine, pharmacology, and the manufacture of nanoscale materials. Based on the large number of nanomaterial applications, a careful understanding of the associated systemic and local toxicity is critically required.
Nanotoxicity
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Author : Susai Rajendran
language : en
Publisher: Elsevier
Release Date : 2020-04-09
Nanotoxicity written by Susai Rajendran and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-09 with Science categories.
Nanotoxicity: Prevention, and Antibacterial Applications of Nanomaterials focuses on the fundamental concepts for cytotoxicity and genotoxicity of nanomaterials. It sheds more light on the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media. The book provides good guidance for toxic prevention methods and management in the manufacture/application/disposal. The book also discusses the potential applications of nanomaterials-based antibiotics. The potential toxic effects of nanomaterials result not only from the type of base materials, but also from their size/ ligands/surface chemical modifications. This book discusses why different classes of nanomaterials display toxic properties, and what can be done to mitigate this toxicity. It also explores how nanomaterials are being used as antimicrobial agents, being used to purify air and water, and counteract a range of infectious diseases. This is an important reference for materials scientists, environmental scientists and biomedical scientists, who are seeking to gain a greater understanding of how nanomaterials can be used to combat toxic agents, and how the toxicity of nanomaterials themselves can best be mitigated. Explains the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media Outlines major methods for mitigating and prevention of nanotoxicity Discusses the applications of nanomaterials-based antibiotics
Immune Response To Cerebral Ischemia Exploring Mechanisms And Potential Treatment Targets
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Author : Xiaoxing Xiong
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-10
Immune Response To Cerebral Ischemia Exploring Mechanisms And Potential Treatment Targets written by Xiaoxing Xiong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-10 with Medical categories.
Handbook Of Immunological Properties Of Engineered Nanomaterials
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Author : Marina Dobrovolskaia
language : en
Publisher: World Scientific
Release Date : 2013
Handbook Of Immunological Properties Of Engineered Nanomaterials written by Marina Dobrovolskaia and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.