Necrosis
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Skin Necrosis
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Author : Luc Téot
language : en
Publisher: Springer
Release Date : 2015-03-16
Skin Necrosis written by Luc Téot and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-16 with Medical categories.
In recent years, wound care has gained increasing recognition as a distinct medical specialty. An understanding of the complex mechanisms involved in wound healing facilitates efficient assessment and treatment of patients with wounds, and skin necrosis can be considered the starting point in the entire healing process. This book is the first to discuss skin necrosis as a symptom related to a broad range of pathologies. Richly illustrated, it primarily provides therapeutic strategies and treatment algorithms for different clinical contexts. All chapters were written by renowned specialists in their respected fields and include detailed sample cases and essential take-home messages. In light of the highly interdisciplinary nature of wound management, Skin Necrosis offers an invaluable resource for wound care practitioners and health care professionals across the fields of surgery, dermatology, internal medicine, and nursing.
Necrotic Cell Death
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Author : Han-Ming Shen
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-29
Necrotic Cell Death written by Han-Ming Shen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-29 with Science categories.
Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.
Necrosis
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Author : Kimberly McCall
language : en
Publisher: Humana
Release Date : 2016-08-23
Necrosis written by Kimberly McCall and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Science categories.
Cell death is an essential process in development, and a major contributor to a wide range of human diseases. Three major classifications of cell death, apoptosis, autophagic cell death and necrosis, have been described for years, and the existence of many more forms of cell death is now accepted. In, Necrosis: Methods and Protocols experts in the field provide a wide range of methods and techniques for the study of necrosis in vitro and in vivo. These include methods and techniques for the analysis of necrosis in mammalian cells, characterization of alternative forms of cell death: entosis and pyroptosis, and analysis of cell death in non-mammalian model sytems and mammalian tissues, including chapters on skin, brain, and heart. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Necrosis: Methods and Protocols describes techniques in an easy to follow manner, with details so that beginners can succeed with challenging techniques.
Cell Death
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Author : Tobias Ntuli
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-12-16
Cell Death written by Tobias Ntuli and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-16 with Science categories.
This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.
Pathogenesis And Mechanisms Of Liver Cell Necrosis
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Author : D. Keppler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Pathogenesis And Mechanisms Of Liver Cell Necrosis written by D. Keppler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The pathogenesis of cell death and necrosis in the liver is a central topic of research in liver disease. A molecular understanding of events and sequences leading to cellular death provides the basis for preventive and therapeutic efforts. This volume originates from a "Workshop on Experimental Liver Injury" held on November 9 and 10, 1974, in Freiburg, Germany. Recent progress in the elucidation of the mode of action includes agents inducing liver cell necrosis by a primary dis turbance of nucleotide and nucleic acid metabolism as well as hepa totoxins characterized by a primary attack on cellular membranes. I hope that this book will contribute to an increasing understanding of disease mechanisms. Freiburg im Breisgau Dietrich Keppler June 1975 Acknowledgments The generous support from Dr. H. Falk, Freiburg, has been a prereqUIsite for the organisation and publication of the meeting on "Pathogenesis and Mechanisms of Liver Cell Necrosis". I wish to express my sincere thanks for this sponsorship. I am indebted to those who acted as chairmen during the meeting: Professors H. Remmer (Tilbingen), M. Frimmer (Giessen), W. Gerok (Freiburg), H. Popper (New York), H. Schimassek (Heidelberg), and K. Decker (Freiburg).
Avascular Necrosis
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Author : Iulian Nusem
language : en
Publisher: Nova Science Publishers
Release Date : 2014
Avascular Necrosis written by Iulian Nusem and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Bones categories.
Although the disease called avascular necrosis (AVN) was discovered in Egyptian mummies, there is a lack of information available in understanding and treating this pathology. AVN is a condition where cellular death of bone components occurs due to an interruption of the blood supply. Nusem discusses the morphopathological appearance of AVN. Avascular necrosis tends to affect young adults and often progresses despite appropriate treatment. Each chapter will provide an overview of the specific systems most commonly used for the anatomical region described therein. Various anatomical locations more commonly involved with AVN are discussed specifically.
Programmed Necrosis
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Author : Adrian T. Ting
language : en
Publisher: Humana
Release Date : 2019-09-06
Programmed Necrosis written by Adrian T. Ting and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-06 with Science categories.
This volume explores the latest techniques and approaches used to study this emerging form of cell death. The chapters in this book cover topics such as distinguishing necroptosis from apoptosis; detecting MLKL oligomerization during programmed necrosis; analyzing the RIPK3 necrosome complex; using RIPK1 kinase small molecule inhibitors in studying necroptosis; monitoring RIPK1 phosphorylation in the TNFR1 signaling complex; and assessing in vivo kidney cell death in glomerular injury. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Programmed Necrosis: Methods and Protocols is a valuable resource for technicians, graduate students, postdoctoral fellows, and other scientists who are pursuing studies in this field.
Aseptic Necrosis Of Bone
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Author : John Knight Davidson
language : en
Publisher:
Release Date : 1976
Aseptic Necrosis Of Bone written by John Knight Davidson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Medical categories.
Tumour Necrosis Factor And Related Cytotoxins
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Author : Gregory R. Bock
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Tumour Necrosis Factor And Related Cytotoxins written by Gregory R. Bock and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Medical categories.
The number of factors implicated in the regulation of cell proliferation and differentiation is already considerable and more are continually being identified. This book concentrates on tumor necrosis factor (cachectin) and lymphotoxin, but includes observations of their interactions with other cytokines, especially the interferons and interleukins. TNF can be either cytostatic or cytotoxic to cultured cell lines, and a variety of mechanisms are proposed, ranging from DNA fragmentation to activation of phospholiopases. TNF is also reported to stimulate the growth of normal fibroblasts in vivo. The in vivo actions of TNF described here include haemorrhagic necrosis of tumors, cachexia, effects on the vasculature, and antiparasitic and antiviral activities. Also presented is some interesting data from the first stages of clinical trials of TNF as an anticancer agent.
Avascular Necrosis Of The Femoral Head Current Trends
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Author : F.S. Santori
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Avascular Necrosis Of The Femoral Head Current Trends written by F.S. Santori and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Avascular Necrosis (AVN) is a disease resulting from temporary or permanent loss of blood supply. It frequently affects the femoral head and in this area, if left untreated, routinely causes premature joint destruction. In the USA, 5 to 10% of cases of hip osteoarthritis requiring total hip replacement are primarily caused by AVN. In 33 to 72% of patients, the disease is bilateral. The peak incidence is between 30 and 60 years of age, and the social costs of this pathology are remarkable. There is therefore increasing interest in hip joint preserving techniques such as conservative treatment through electromagnetic fields and shockwaves as well as joint preserving surgical techniques. This volume aims to present a complete overview of the current knowledge on AVN including therapeutic options.