Neonatal Encephalopathy And Cerebral Palsy
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Neonatal Encephalopathy And Cerebral Palsy
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Author : American College of Obstetricians and Gynecologists. Task Force on Neonatal Encephalopathy and Cerebral Palsy
language : en
Publisher: American College of Obstetricians and Gynecologists Women's Health Care Physicians
Release Date : 2003
Neonatal Encephalopathy And Cerebral Palsy written by American College of Obstetricians and Gynecologists. Task Force on Neonatal Encephalopathy and Cerebral Palsy and has been published by American College of Obstetricians and Gynecologists Women's Health Care Physicians this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Health & Fitness categories.
This monograph explores the mechanisms and timing of possible etiologic events that contribute to fetal and neonatal neurologic injury. the report presents evidence that most cases of cerebral palsy are a result of multifactorial and unpreventable causes that occur during fetal development or in the newborn after delivery, and not a result of an isolated intrapartum hypoxic event. the report contains a set of criteria that may be used to define (or rule out) an acute intrapartum hypoxic event sufficient to cause or suggest cerebral palsy.
Neonatal Encephalopathy And Neurologic Outcome
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Author : American College of Obstetricians and Gy
language : en
Publisher: American College of Obstetricians and Gynecologists Women's Health Care Physicians
Release Date : 2014
Neonatal Encephalopathy And Neurologic Outcome written by American College of Obstetricians and Gy and has been published by American College of Obstetricians and Gynecologists Women's Health Care Physicians this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Medical categories.
Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.
Acute Perinatal Asphyxia In Term Infants
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Author : Linda L. Wright
language : en
Publisher: DIANE Publishing
Release Date : 1997-07
Acute Perinatal Asphyxia In Term Infants written by Linda L. Wright and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-07 with categories.
Reviews the current knowledge of the definition & diagnosis of acute perinatal asphyxia in term infants in order to develop operational & specific criteria to be tested in new studies. Summarized information currently available on this topic. Contents: scientific basis of brain injury in acute perinatal asphyxia; clinical assessment -- obstetrics; clinical assessment -- neonatal; interventions (conventional management; neuronal rescue & neuronal prohylaxis; glutamate antagonists, calcium channel blockers & Allopurinol); clinical studies of long-term outcome; clinical research. Charts & tables.
Birth Asphyxia An Issue Of Clinics In Perinatology E Book
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Author : Beena D. Kamath-Rayne
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-08-19
Birth Asphyxia An Issue Of Clinics In Perinatology E Book written by Beena D. Kamath-Rayne and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-19 with Medical categories.
The Guest Editors have assembled top experts to provide the most current and clinically relevant articles devoted to Birth Asyphyxia. Articles in this issue are devoted to: Neonatal Transition After Birth; Pathophysiology of Birth Asphyxia; Perinatal Asphyxia from the Obstetrical Standpoint: Diagnosis and Interventions; Stillbirths: U.S. and Global Perspectives; Novel Approaches to Resuscitation and the Impact on Birth Asphyxia; Multiorgan Dysfunction and its Management After Birth Asphyxia; Neonatal Encephalopathy and Update on Therapeutic Hypothermia and Other Novel Therapeutics; Biomarkers in Neonatal Encephalopathy; Imaging and Other Diagnostics in Neonatal Encephalopathy; Asphyxia in the Premature Infant; The role of the NeoNeuro Unit for Birth Asphyxia; Long-term Cognitive Outcomes of Birth Asphyxia and the Contribution of Identified Perinatal Asphyxia to Cerebral Palsy; Global Burden, Epidemiologic Trends, and Prevention of Intrapartum Related Deaths in Low-resource Settings; and Neonatal Resuscitation in Low-resource Settings.
Epidemiology Of Cerebral Palsy And Unfavourable Neurodevelopmental Outcome In Child Population Of Tartu City And County Estonia
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Author : Tiina Stelmach
language : en
Publisher:
Release Date : 2006
Epidemiology Of Cerebral Palsy And Unfavourable Neurodevelopmental Outcome In Child Population Of Tartu City And County Estonia written by Tiina Stelmach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Cerebral palsy categories.
Improving Outcomes In Cerebral Palsy With Early Intervention New Translational Approaches
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Author : Anna Purna Basu
language : en
Publisher: Frontiers E-books
Release Date : 2015-03-30
Improving Outcomes In Cerebral Palsy With Early Intervention New Translational Approaches written by Anna Purna Basu and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-30 with Medicine (General) categories.
The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life. CP arises from insults to the sensorimotor cortex, subcortical axon tracts and subplate. The aetiology is complex and often multifactorial. The outcome is not simply a loss of voluntary control due to disruption of descending pathways, but also involves abnormal development of reflex and corticospinal circuitry. CP may be viewed as aberrant plasticity in response to a lesion, indeed, abnormalities in movement are subtle at first but develop subsequently. It is misleading to suppose that developmental mechanisms are self-reparative. The challenge is to understand activitydependent fine tuning of neural circuitry during normal development and to find how to promote desirable plasticity whilst limiting undesirable effects following developmental lesions. However, before proposing interventions, we have to develop our ability to predict the severity of neonatal insults. We solicited a variety of articles, including long and short reviews, original research and opinion pieces, from both basic scientists and clinicians. Likewise we, as editors, have complementary knowledge and experience in this area. Anna Basu is an academic pediatric neurologist and Gavin Clowry is a developmental neuroscientist.
Fetal And Neonatal Brain Injury
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Author : David K. Stevenson
language : en
Publisher: Cambridge University Press
Release Date : 2017-12-21
Fetal And Neonatal Brain Injury written by David K. Stevenson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-21 with Medical categories.
Authoritative, practical clinical text giving clear management advice on diagnosis, treatment and outcomes of all fetal and neonatal brain injuries.
Neonatal Neural Rescue
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Author : A. David Edwards
language : en
Publisher: Cambridge University Press
Release Date : 2013-04-04
Neonatal Neural Rescue written by A. David Edwards and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-04 with Medical categories.
Worldwide more than one million babies die annually from perinatal asphyxia and its associated complications such as neonatal encephalopathy – one of the major causes of cerebral palsy and cognitive deficiencies in children aside from prematurity. Cooling the head – or the entire body – minimizes neuronal death, enabling the neonatal brain to be 'rescued' thus greatly improving developmental outcomes. Hypothermic neural rescue therapy has revolutionized the treatment of this condition and is a major recent achievement in neonatal medicine. This landmark book provides a brief scientific underpinning of hypothermic neural rescue therapy and lays out the evidence base for good practice. Internationally recognized authorities give practical advice, drawn from personal experience, on how to deliver hypothermia in the neonatal intensive care unit. A valuable addition to any neonatal unit, this is essential reading for neonatologists, neonatal nurses and paediatric neurologists.
Cell Therapy For Perinatal Brain Injury
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Author : Haruo Shintaku
language : en
Publisher: Springer
Release Date : 2018-03-01
Cell Therapy For Perinatal Brain Injury written by Haruo Shintaku and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-01 with Medical categories.
This book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction. These diseases pose serious challenges for neonatologists and neurologists, because the severe sequelae lead to decreasing QOL for patients and their families. Accordingly, new treatments for neonatal ischemic diseases are needed all over the world. The book develops new effective therapies combined with hypothermia therapy, an established treatment for HIE. After reviewing past approaches, it presents cutting-edge topics in cell therapy, one of the most promising candidates for treating neonatal ischemic disease. Cell Therapy for Neonatal Ischemic Disease will offer readers a better understanding of the current state of the art in this field from bench to bedside, and inspire researchers and physicians to further explore this evolving therapy.
Pediatric Neurology Part I
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Author : Stéphane Marret
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-04-24
Pediatric Neurology Part I written by Stéphane Marret and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-24 with Medical categories.
Cerebral palsy (CP), defined as a group of nonprogressive disorders of movement and posture, is the most common cause of severe neurodisability in children. Understanding its physiopathology is crucial to developing some protective strategies. Interruption of oxygen supply to the fetus or brain asphyxia was classically considered to be the main causal factor explaining later CP. However several ante-, peri-, and postnatal factors could be involved in the origins of CP syndromes. Congenital malformations are rarely identified. CP is most often the result of environmental factors, which might interact with genetic vulnerabilities, and could be severe enough to cause the destructive injuries visible with standard imaging (i.e., ultrasonographic study or MRI), predominantly in the white matter in preterm infants and in the gray matter and the brainstem nuclei in full-term newborns. Moreover they act on an immature brain and could alter the remarkable series of developmental events. Biochemical key factors originating in cell death or cell process loss, observed in hypoxic−ischemic as well as inflammatory conditions, are excessive production of proinflammatory cytokines, oxidative stress, maternal growth factor deprivation, extracellular matrix modifications, and excessive release of glutamate, triggering the excitotoxic cascade. Only two strategies have succeeded in decreasing CP in 2-year-old children: hypothermia in full-term newborns with moderate neonatal encephalopathy and administration of magnesium sulfate to mothers in preterm labor.