Neural Circuit Development And Function In The Healthy And Diseased Brain
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Neural Circuit Development And Function In The Healthy And Diseased Brain
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-05-06
Neural Circuit Development And Function In The Healthy And Diseased Brain written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-06 with Science categories.
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 3 sections include coverage of: mechanisms that control the assembly of neural circuits in specific regions of the nervous system, multiple aspects of cognitive development, and disorders of the nervous system arising through defects in neural development
Comprehensive Developmental Neuroscience
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Author : John L. R. Rubenstein
language : en
Publisher: Academic Press is
Release Date : 2013
Comprehensive Developmental Neuroscience written by John L. R. Rubenstein and has been published by Academic Press is this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Developmental neurobiology categories.
Neural Circuit And Cognitive Development
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Author : Bin Chen
language : en
Publisher: Academic Press
Release Date : 2020-06-10
Neural Circuit And Cognitive Development written by Bin Chen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-10 with Psychology categories.
Neural Circuit and Cognitive Development, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume is devoted mainly to anatomical and functional development of neural circuits and neural systems and cognitive development. Understanding the critical role these changes play in neurodevelopment provides the ability to explore and elucidate the underlying causes of neurodevelopmental disorders and their effect on cognition. This series is designed to fill the knowledge gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. - Features leading experts in various subfields as section editors and article authors - Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship - Includes coverage of mechanisms that control the assembly of neural circuits in specific regions of the nervous system and multiple aspects of cognitive development
Phospholipases In Health And Disease
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Author : Paramjit S. Tappia
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-13
Phospholipases In Health And Disease written by Paramjit S. Tappia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-13 with Science categories.
Phospholipases generate lipid signaling molecules through their hydrolytic action on phospholipids and are known to regulate function of a variety of cells under normal and diseased conditions. While several physiological, biochemical and molecular techniques have identified key players involved in different disease processes, phospholipases have also emerged as critical players in the pathogenesis of a number of different diseases including cancer and heart disease. In addition, phospholipases are also implicated in such conditions as brain disorder/injury, kidney and immune cell dysfunction. Phospholipases in Health and Disease is a compilation of review articles dedicated to the study of the field with respect to biochemical and molecular mechanisms of normal and abnormal cell function. The wide range of area covered here is of interest to basic research scientists, clinicians and graduate students, who are engaged in studying pathophysiological basis of a variety of diseases. Furthermore, this book highlights the potential of the different phospholipases as therapeutic targets as well as part of prevention strategies. Twenty three articles in this book are organized in four sections that are designed to emphasize the most characterized forms of the phospholipases in mammalian cells. The first section discusses general aspect of phospholipases. Section two covers the role and function of phospholipase A in different pathophysiological conditions. The third section is focussed on phospholipase C which is believed to play a central role in transmembrane signaling. The final section covers phospholipase D which is present in a variety of different cells. The book illustrates that the activation of phospholipases is of fundamental importance in signal transduction affecting cell function. Overall, this book discusses the diverse mechanisms of phospholipase mediated signal transduction in different pathophysiological conditions and raises the possibility of specific forms of phospholipases serving as novel targets for drug development.
Imaging And Monitoring Astrocytes In Health And Disease
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Author : Carole Escartin
language : en
Publisher: Frontiers Media SA
Release Date : 2014-11-25
Imaging And Monitoring Astrocytes In Health And Disease written by Carole Escartin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-25 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Astrocytes are key cellular partners to neurons in the brain. They play an important role in multiple processes such as neurotransmitter recycling, trophic support, antioxidant defense, ionic homeostasis, inflammatory modulation, neurovascular and neurometabolic coupling, neurogenesis, synapse formation and synaptic plasticity. In addition to their crucial involvement in normal brain physiology, it is well known that astrocytes adopt a reactive phenotype under most acute and chronic pathological conditions such as ischemia, trauma, brain cancer, epilepsy, demyelinating and neurodegenerative diseases. However, the functional impact of astrocyte reactivity is still unclear. During the last decades, the development of innovative approaches to study astrocytes has significantly improved our understanding of their prominent role in brain function and their contribution to disease states. In particular, new genetic tools, molecular probes, and imaging techniques that achieve high spatial and temporal resolution have revealed new insight into astrocyte functions in situ. This Research Topic provides a collection of cutting-edge techniques, approaches and models to study astrocytes in health and disease. It also suggests new directions to achieve discoveries on these fascinating cells.
Synaptic Assembly And Neural Circuit Development
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Author : Jaewon Ko
language : en
Publisher: Frontiers Media SA
Release Date : 2018-11-02
Synaptic Assembly And Neural Circuit Development written by Jaewon Ko and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with categories.
Physiology And Function Of Glial Cells In Health And Disease
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Author : El-Mansoury, Bilal
language : en
Publisher: IGI Global
Release Date : 2023-12-18
Physiology And Function Of Glial Cells In Health And Disease written by El-Mansoury, Bilal and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-18 with Science categories.
Glial cells, including microglia, astrocytes, oligodendrocytes, and their progenitors NG2-glia, serve as key players in maintaining structural integrity and complex brain homeostasis. They actively participate in neurotransmission, energy metabolism, synaptic plasticity, neurogenesis, ion balance, immune defense, and the clearance of neuronal debris. However, the physiological functions of glial cells are often compromised in aging, neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, and multiple sclerosis, as well as in gliomas, brain tumors demanding specialized understanding for effective therapeutic interventions. Physiology and Function of Glial Cells in Health and Disease provides a comprehensive exploration of the vital role played by glial cells in maintaining neural homeostasis within the central nervous system (CNS). This book delves into the intricate interaction between glial cells and neurons, shedding light on their essential contributions to neural function and overall brain health. The book also highlights emerging research on astrocyte reprogramming for the management of neurodegenerative diseases, offering a glimpse into potential future therapies. This book is an essential resource for researchers, clinicians, and students in the field of neuroscience. Its academic tone, coupled with in-depth discussions and cutting-edge insights, makes it a valuable reference for anyone seeking a comprehensive understanding of the role of glial cells in both health and disease.
Astrocyte Neuron Interactions In Health And Disease
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Author : Elena Blanco-Suarez
language : en
Publisher: Springer Nature
Release Date : 2024-08-27
Astrocyte Neuron Interactions In Health And Disease written by Elena Blanco-Suarez and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-27 with Science categories.
This new book extensively explores a range of topics related to astrocyte-neuron interactions under multiple conditions, in both health and disease. These include the types of interactions that occur during development and the establishment of neuronal circuits that underlie learning and memory formation in various animal models as well as humans. Furthermore, the book addresses topics on how these interactions go awry in disease and injury. In addition, the authors propose inspiring new avenues to explore therapeutic approaches using astrocytes as targets. A cadre of international experts presents a broad range of views on the state-of-the-art of astrocyte-neuron interactions.
The Role Of Astroglia And Oligodendroglia In Cns Development Plasticity And Disease Novel Tools And Investigative Approaches
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Author : Enrica Boda
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-31
The Role Of Astroglia And Oligodendroglia In Cns Development Plasticity And Disease Novel Tools And Investigative Approaches written by Enrica Boda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-31 with Science categories.
Neuromodulatory Control Of Spinal Function In Health And Disease
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Author : Brian R. Noga
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-20
Neuromodulatory Control Of Spinal Function In Health And Disease written by Brian R. Noga and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-20 with categories.