Neural Immune Interactions In Brain Function And Alcohol Related Disorders
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Neural Immune Interactions In Brain Function And Alcohol Related Disorders
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Author : Changhai Cui
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-14
Neural Immune Interactions In Brain Function And Alcohol Related Disorders written by Changhai Cui and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-14 with Medical categories.
Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and an altered neuroimmune profile. This book integrates emerging knowledge on neural-immune interactions with key discoveries in alcohol research and provides a comprehensive overview of neural-immune interactions in brain function and behavior associated with alcohol use disorders. While Neural–Immune Interaction in Brain Function and Alcohol Related Disorders focuses on neural-immune interactions in areas directly related to alcohol use disorders, it is not intended to be all inclusive. Several areas, including sleep disorders, pain, and cholinergic anti-inflammatory pathways, are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts.
Effects Of Alcohol On The Brain Across The Lifespan
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Author : C. Fernando Valenzuela
language : en
Publisher: Springer Nature
Release Date : 2025-03-24
Effects Of Alcohol On The Brain Across The Lifespan written by C. Fernando Valenzuela and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-24 with Science categories.
This book delves into the intricate relationship between alcohol and the brain across different stages of life, offering groundbreaking insights from preclinical and clinical studies. From prenatal development to the complexities of aging, it unravels how alcohol interacts with neural networks, neurotransmitters, and cellular processes that govern behavior. Starting with the prenatal period, the book will explore the effects of alcohol on the developing brain, shedding light on the potential cognitive and behavioral consequences that may persist into adulthood. It unravels the intricate mechanisms through which alcohol impacts neurodevelopment, including alterations in brain structure, neuronal connectivity, and synaptic plasticity. Moving into adolescence and early adulthood, the book will examine how alcohol affects crucial brain regions involved in decision-making, impulse control, and memory formation. It will explore the neurological changes associated with excessive alcohol consumption during this sensitive period, offering insights into the long-term risks of alcohol abuse and addiction. Throughout middle adulthood and into later life, the book will delve into the nuanced interplay between alcohol and age-related disorders, including neurodegenerative disorders, such as Alzheimer's disease and dementia. Researchers in neuroscience, psychology, and related fields will find this book invaluable for its comprehensive exploration of alcohol's effects on the brain. It is an essential read for scholars, practitioners, and anyone interested in understanding the profound implications of alcohol consumption across the lifespan.
The Gut Brain Axis
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Author : Niall Hyland
language : en
Publisher: Academic Press
Release Date : 2016-05-13
The Gut Brain Axis written by Niall Hyland and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-13 with Medical categories.
The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. - Focuses on specific areas in which the microbiota has been implicated in gut-brain communication - Examines common mechanisms and pathways by which the microbiota may influence brain and behavior - Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior
Perspectives And Recent Advances In Fetal Alcohol Spectrum Disorders Research
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Author : Hermes H. Yeh
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-03
Perspectives And Recent Advances In Fetal Alcohol Spectrum Disorders Research written by Hermes H. Yeh and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-03 with Science categories.
Alcohol
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Author : George F. Koob
language : en
Publisher: Academic Press
Release Date : 2021-07-07
Alcohol written by George F. Koob and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-07 with Psychology categories.
A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Alcohol, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. - Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction - Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle - Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol
Neuroimmune Signaling In Drug Actions And Addictions
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Author :
language : en
Publisher: Academic Press
Release Date : 2014-08-28
Neuroimmune Signaling In Drug Actions And Addictions written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-28 with Psychology categories.
This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Neuroimmune Signaling in Drug Actions and Addictions. - This book looks at neuroimmune signaling in drug actions and addictions in the light of the newest scholarly discoveries and insights
Neuroscience Of Alcohol
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Author : Victor R Preedy
language : en
Publisher: Academic Press
Release Date : 2019-03-19
Neuroscience Of Alcohol written by Victor R Preedy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-19 with Psychology categories.
Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world's most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. - Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function - Discusses alcohol use as a component of dual-use and poly addictions - Outlines numerous screening and treatment strategies for alcohol misuse - Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects
Fetal Development
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Author : Nadja Reissland
language : en
Publisher: Springer
Release Date : 2016-03-15
Fetal Development written by Nadja Reissland and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-15 with Psychology categories.
This book provides an overview of fetal psychobiological research, focusing on brain and behavior, genetic and epigenetic factors affecting both short and long-term development, and technological breakthroughs in the field. These focal points intersect throughout the chapters, as in the challenges of evaluating the fetal central nervous system, the myriad impacts of maternal stressors and resiliencies, and the salience of animal studies. It also discusses specific monitoring and assessment methods, including cardiotocography, biomagnetometry, 4D ultrasound, in utero MRI, and the KANET test. Spanning assessment, identification, and pre- and postnatal intervention, the book weighs the merits of standardized evaluations and argues for more integrative research in the future. Included in the coverage: Effects on the fetus of maternal anxiety, depression, and stress during pregnancy. Clinical and experimental research in human fetuses and animal models. Observational research including the use of behaviors in developing tests to assess fetal health. Fetal auditory processing and implications for language development. Fetal effects of prenatal exposure to selective SRI antidepressant exposure. Structural and functional imaging of the prenatal brain. The effects of alcohol exposure on fetal development. Fetal Development: Research on Brain and Behavior, Environmental Influences, and Emerging Technologies is an essential resource for researchers, clinicians and related professionals, as well as students in a wide range of fields such as developmental psychology, pediatric and obstetrical medicine, neuroscience, nursing, social work, and early childhood education.
Glutamate And Neuropsychiatric Disorders
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Author : Zoran M. Pavlovic
language : en
Publisher: Springer Nature
Release Date : 2022-04-10
Glutamate And Neuropsychiatric Disorders written by Zoran M. Pavlovic and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-10 with Medical categories.
This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD), Posttraumatic Stress Disorder (PTSD), Alzheimer’s Dementia, Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD), Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple Sclerosis, Parkinson’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders. Moreover, the book includes an extensive overview of glutamatergic treatments already available on the market, and those which are currently in pharmaceutical drug development pipelines. The primary beneficiaries will be neurology and psychiatry specialists and residents, neuroscientists, neuropharmacologists, pharmaceutical industry and clinical research organization professionals, academics, and clinicians working with psychiatric and neurological patients with comorbidities such as cardiologists, pulmonologists, and endocrinologists. This book will also appeal to psychiatry and neurology subspecialists and clinicians working in neuroscience labs seeking an easy-to-understand yet comprehensive overview of contemporary evidence-based clinical insights backed by basic science (preclinical) research evidence. Given its scope, the book is also a unique and indispensable resource for both preclinical and clinical neuroscientists, medical advisors, and clinical research specialists in the pharmaceutical industry. In addition, it will appeal to neuroscience and neuropsychopharmacology students and guide them through the complexities of glutamate involvement in the pathophysiology of the most common debilitating brain diseases with high unmet medical needs.
Neuropathology Of Drug Addictions And Substance Misuse Volume 1
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Author : Victor R Preedy
language : en
Publisher: Academic Press
Release Date : 2016-03-07
Neuropathology Of Drug Addictions And Substance Misuse Volume 1 written by Victor R Preedy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-07 with Psychology categories.
Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader's knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. - Provides a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions - Fills an existing gap in the literature by proving a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse - Includes a list of abbreviations, abstracts, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references in each chapter - Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and the genome to whole body