Neurobiological Biomarkers For Developing Novel Treatments Of Substance And Non Substance Addiction
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Neurobiological Biomarkers For Developing Novel Treatments Of Substance And Non Substance Addiction
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Author : Yanhui Liao
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-03
Neurobiological Biomarkers For Developing Novel Treatments Of Substance And Non Substance Addiction written by Yanhui Liao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-03 with Medical categories.
Community Series In Neurobiological Biomarkers For Developing Novel Treatments Of Substance And Non Substance Addiction Volume Ii
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Author : Yanhui Liao
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-17
Community Series In Neurobiological Biomarkers For Developing Novel Treatments Of Substance And Non Substance Addiction Volume Ii written by Yanhui Liao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-17 with Medical categories.
This Research Topic is the second volume of the 'Community Series in Neurobiological Biomarkers for Developing Novel Treatments of Substance and Non-Substance Addiction'. Please see the first volume here. Many people suffer from substance (from nicotine or alcohol to heroin, methamphetamine, cocaine, etc) or non-substance (from gaming/gambling to shopping, internet, smartphone, etc) addiction. Both types of addiction are associated with severe health, economic and social consequences and are far too often result in both familial and personal tragedies. Unfortunately, current treatments are not very effective for either substance or non-substance addiction so novel treatments are desperately needed. For example, for nicotine addiction, despite very well-documented health risks of cigarette smoking and its economic and societal costs, globally, more than 30% of males still smoke, and although many smokers desire to quit, only approximately 5-30% will achieve abstinence with 6 months or more of the best available current treatments. And the story for nicotine addiction is far from unique, presenting a huge challenge for the entire addiction field. Therefore, there is a vital need to improve outcomes for the treatment of both substance and non-substance addictions. Recent work exploring neurobiological mechanisms of the treatment response at the molecular, cellular and systems levels with a broad range of technologies, such as Magnetic Resonance Imaging (MRI), genetics and genomics, have opened new avenues for developing novel treatments through the detection of neurobiological biomarkers predicting efficacious outcomes in addicted patients.
Neuroimaging In Addiction
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Author : Bryon Adinoff
language : en
Publisher: John Wiley & Sons
Release Date : 2011-11-02
Neuroimaging In Addiction written by Bryon Adinoff and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-02 with Medical categories.
Neuroimaging in Addiction presents an up-to-date, comprehensive review of the functional and structural imaging human studies that have greatly advanced our understanding of this complex disorder. Approaching addiction from a conceptual rather than a substance-specific perspective, this book integrates broad neuropsychological constructs that consider addiction as a neuroplastic process with genetic, developmental, and substance-induced contributions. The internationally recognized contributors to this volume are leaders in clinical imaging with expertise that spans the addiction spectrum. Following a general introduction, an overview of neural circuitry and modern non-invasive imaging techniques provides the framework for subsequent chapters on reward salience, craving, stress, impulsivity and cognition. Additional topics include the use of neuroimaging for the assessment of acute drug effects, drug-induced neurotoxicity, non-substance addictive behaviors, and the application of imaging genetics to identify unique intermediate phenotypes. The book concludes with an exploration of the future promise for functional imaging as guide to the diagnosis and treatment of addictive disorders. Scientists and clinicians will find the material in this volume invaluable in their work towards understanding the addicted brain, with the overall goal of improved prevention and treatment outcomes for patients. Features a Foreword by Edythe London, Director of the Center for Addictive Behaviors, University of California at Los Angeles.
Charney Nestler S Neurobiology Of Mental Illness
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Author : Dennis S. Charney
language : en
Publisher: Oxford University Press
Release Date : 2018
Charney Nestler S Neurobiology Of Mental Illness written by Dennis S. Charney and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
Preceded by Neurobiology of mental illness / edited by Dennis S. Charney ... [et al.]. 4th ed. 2013.
Handbook Of Neuroethics
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Author : Jens Clausen
language : en
Publisher: Springer
Release Date : 2014-10-28
Handbook Of Neuroethics written by Jens Clausen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-28 with Philosophy categories.
Based on the study of neuroscientific developments and innovations, examined from different angles, this Handbook provides a comprehensive overview of the international neuroethical debate, and offers unprecedented insights into the impact of neuroscientific research, diagnosis, and therapy. Neuroethics – as a multi-disciplinary and inter-disciplinary endeavor – examines the implications of the neurosciences for human beings in general and for their self-understanding and their social interactions in particular. The range of approaches adopted in neuroethics and thus in this handbook includes but is not limited to historical, anthropological, ethical, philosophical, theological, sociological and legal approaches. The Handbook deals with a plethora of topics, divided into in three parts: the first part contains discussions of theories of neuroethics and how neuroscience impacts on our understanding of personal identity, free will, and other philosophical concepts. The second part is dedicated to issues involved in current and future clinical applications of neurosciences, such as brain stimulation, brain imaging, prosthetics, addiction, and psychiatric ethics. The final part deals with neuroethics and society and includes chapters on neurolaw, neurotheology, neuromarketing, and enhancement.
Neurobiology Of Bipolar Disorder
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Author : Joao Quevedo
language : en
Publisher: Academic Press
Release Date : 2020-11-25
Neurobiology Of Bipolar Disorder written by Joao Quevedo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Medical categories.
The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder
Addiction
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Author : Chris Chandler
language : en
Publisher: SAGE
Release Date : 2018-10-29
Addiction written by Chris Chandler and has been published by SAGE this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-29 with Psychology categories.
Addiction: A biopsychosocial perspective provides students with an evidence-based approach to addiction whilst covering a broad range of topics, critical perspectives and influential theories in addiction. With chapters discussing key theories, psychological, biological and societal aspects of addiction, this is a highly accessible and essential resource for students and researchers that: Offers an evidence-based discussion of addiction Addresses the neuroscience and psychology of addiction Provides a critical account of the science and research in addiction Includes chapter overviews and summaries, learning aims and case studies to help students in their study
Substance Use Disorders
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Author : Michael A. Nader
language : en
Publisher: Springer Nature
Release Date : 2020-05-19
Substance Use Disorders written by Michael A. Nader and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-19 with Medical categories.
The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes. The research and outcomes described in this book represent important principles related to identifying and understanding factors related to substance use disorders. The first section is dedicated to methodology including population-based surveys, basic neuroanatomy, chemistry, molecular biology, behavioral models and brain imaging. The second section utilizes this methodology in research related to opioids, cocaine, marijuana, alcohol and nicotine. The book is aimed at both professionals (academics, clinicians, practitioners) and students or trainees.
Stress And Addiction
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Author : Mustafa al'Absi
language : en
Publisher: Elsevier
Release Date : 2011-04-28
Stress And Addiction written by Mustafa al'Absi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-28 with Psychology categories.
Stress is one of the most commonly reported precipitants of drug use and is considered the number one cause of relapse to drug abuse. For the past several decades, there have been a number of significant advances in research focusing on the neurobiological and psychosocial aspects of stress and addiction; along with this growth came the recognition of the importance of understanding the interaction of biological and psychosocial factors that influence risk for initiation and maintenance of addictive behaviors. Recent research has started to specifically focus on understanding the nature of how stress contributes to addiction - this research has influenced the way we think about addiction and its etiological factors and has produced exciting possibilities for developing effective intervention strategies; to date there has been no available book to integrate this literature. This highly focused work integrates and consolidates available knowledge to provide a resource for researchers and practitioners and for trainees in multiple fields. Stress and Addiction will help neuroscientists, social scientists, and mental health providers in addressing the role of stress in addictive behaviors; the volume is also useful as a reference book for those conducting research in this field. Integrates theoretical and practical issues related to stress and addiction Includes case studies illustrating where an emotional state and addictive behavior represent a prominent feature of the clinical presentation Cross-disciplinary coverage with contributions by by scientists and practitioners from multiple fields, including psychology, neuroscience, neurobiology, and medicine
Improving And Accelerating Therapeutic Development For Nervous System Disorders
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2014-02-06
Improving And Accelerating Therapeutic Development For Nervous System Disorders written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-06 with Medical categories.
Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.