Neuroglia Function And Pathology

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Neuroglia Function And Pathology

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Author : Alexei Verkhratsky
language : en
Publisher: Elsevier
Release Date : 2023-05-12

Neuroglia Function And Pathology written by Alexei Verkhratsky and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-12 with Medical categories.

Diverse specialised neuroglial cells guarantee the development, preservation, and health of the central nervous system, the peripheral nervous system, the enteric nervous system, and the special senses. In the central nervous system, it is the astrocytes, oligodendrocytes, and microglia that safeguard nerve cell function and integrity that controls all behaviours and encompasses the cerebral cortex of the brain which is the root of humanity. In the peripheral nervous system, Schwann cells play the leading role, together with satellite glial cells of the sensory and autonomic ganglia, ensuring correct communication between the organs and tissues with the brain and the spinal cord. In the enteric nervous system, specialised enteric glial cells maintain all aspects of gastrointestinal function. Then there are distinctive glial cells of the special senses that ensure how the body perceives and reacts to its environment. In pathology, neuroglia strive to protect the diverse cellular components of the nervous system and are responsible for a proactive programme of posttraumatic restructuring that is aimed at recovery of life-sustaining function. Neuroglia: Function and Pathology provides a highly original and comprehensive account of the physiology and pathophysiology of glial cells in the central and peripheral nervous systems. The first part of the book provides a far-reaching description of glial cell form and function, from their evolution in invertebrates to their complexity in humans, encompassing the developmental origin of the varied glial cell types and their diversity of morphology, molecular biology and cellular physiology. The second part of the book is devoted to an all-embracing evaluation of glial cell pathophysiology, commencing with definitive explanations of the fundamental pathologies of the main glial cell types, and ending in a systematic examination of glial contributions to specific neurological diseases. This book emphasises the central roles played by the different classes of neuroglial cells in the progression and outcome of neurological disorders of the central and peripheral nervous systems and highlights potential of glial cells as therapeutic targets. The book contains more than 2500 key references from over 150 years of glial research and is superbly illustrated with over 350 original and explanatory full colour figures that describe the diverse characteristics and properties of glial cells in health and disease. Under the same cover, this book combines an authoritative reference book for research and clinical neuroscientists and at the same time serves as an instructive textbook for students of neuroscience, from undergraduates to postgraduates. - Single volume covering key aspects of glial cell physiology and pathology - In depth overview of the history of glial cell research - Comprehensive review of glial cell physiology and pathology - Authoritative special chapters on the major neurological diseases - Full colour throughout, with 360 illustrations

Glial Physiology And Pathophysiology

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Author : Alexei Verkhratsky
language : en
Publisher: John Wiley & Sons
Release Date : 2013-04-15

Glial Physiology And Pathophysiology written by Alexei Verkhratsky and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-15 with Medical categories.

Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverage includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role of glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

Brain Neurotrauma

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Author : Firas H. Kobeissy
language : en
Publisher: CRC Press
Release Date : 2015-02-25

Brain Neurotrauma written by Firas H. Kobeissy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-25 with Medical categories.

With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Enteric Glia

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Author : Brian D. Gulbransen
language : en
Publisher: Biota Publishing
Release Date : 2014-07-01

Enteric Glia written by Brian D. Gulbransen and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Medical categories.

The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

Neuroglia In Neurologic And Psychiatric Disorders Part Ii

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Author :
language : en
Publisher: Elsevier
Release Date : 2025-03-28

Neuroglia In Neurologic And Psychiatric Disorders Part Ii written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-28 with Medical categories.

Neuroglia in Neurologic and Psychiatric Disorders, Part II discusses glia relative to neurologic and psychiatric disorders, emphasizing cross-disease-glial cell dysfunctions. Driven by advances in genetics, transcriptomics, electrophysiologic and imaging techniques, as well as by the increase in knowledge on neuropathologic features and underlying disease mechanisms, this book bridges the gap between neuroglia basic science and neuroglia clinical research. - Provides an overview of neuroglia biology - Identifies neuroglia dysfunction in neurologic and psychiatric disorders - Covers ALS, dementia, Alzheimer, Parkinson, Huntington diseases and more - Includes TBI, Stroke, COVID - Encompasses disorders of mood, eating, sleep, anxiety, schizophrenia, autism, and more

Neuroglia In The Healthy Nervous System Part I

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Author :
language : en
Publisher: Elsevier
Release Date : 2025-03-22

Neuroglia In The Healthy Nervous System Part I written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-22 with Medical categories.

Neuroglia in the Healthy Nervous System, Part I provides insights into newly emerging developments in neuroglia biology, focusing on the healthy nervous system. Driven by advances in genetics, transcriptomics, electrophysiological, and imaging techniques, this volume bridges the gap between neuroglia basic science and neuroglia clinical research. The book provides an overview of neuroglia biology, highlighting emerging technologies used to unravel the role of neuroglial cells in specific brain functions. The book also discusses strategies using neuroglia as a therapeutic target. - Provides an overview of neuroglia biology - Identifies normal neuroglia function in the healthy nervous system - Includes animal and human research - Discusses transcriptomic, electrophysiological, and imaging techniques to study neuroglia - Covers research using neuroglia as a therapeutic target

Physiology And Pathophysiology Of Oligodendroglia

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Author : Chenju Yi
language : en
Publisher: Springer Nature
Release Date : 2025-06-11

Physiology And Pathophysiology Of Oligodendroglia written by Chenju Yi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-11 with Science categories.

This single volume provides a comprehensive description of oligodendroglia, the neural cells responsible for myelination of axons throughout the central nervous system. Myelinated axons create the white matter (connectome) of the human brain and spinal cord, which connect and synchronize hundreds of billions of neurons, thus defining the information processing function of the central nervous system. Oligodendrocytes and myelination play an essential role in regulating every bodily function and behavior. Damage to white matter, myelin, and oligodendrocytes results in severe diseases of the CNS. Pathology and Pathophysiology of Oligodendroglia, presented by the major authorities in the field, is the very first reference to combine, under a single cover, a full and detailed description of the physiology and pathophysiology of oligodendroglia, with a particular emphasis on neurodegenerative diseases.

Physiology And Pathology Of Neuroglia

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Author : Reyes-Haro
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-07

Physiology And Pathology Of Neuroglia written by Reyes-Haro and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-07 with Science categories.

Neuroglia

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Author : Sergey Kasparov
language : en
Publisher: MDPI
Release Date : 2019-06-17

Neuroglia written by Sergey Kasparov and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-17 with Medical categories.

Neuroglia is now published as part of Brain Sciences with a new section Editor-in-Chief Prof. Sergey Kasparov.

Glial Physiology And Pathophysiology

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Author : Alexei Verkhratsky
language : en
Publisher: John Wiley & Sons
Release Date : 2013-01-31

Glial Physiology And Pathophysiology written by Alexei Verkhratsky and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-31 with Medical categories.

Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides