Neuroglia Molecular Mechanisms In Psychiatric Disorders

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Neuroglia Molecular Mechanisms In Psychiatric Disorders

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Author : Caterina Scuderi
language : en
Publisher: Frontiers Media SA
Release Date : 2019-01-21

Neuroglia Molecular Mechanisms In Psychiatric Disorders written by Caterina Scuderi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-21 with categories.

Neuropsychiatric disorders have long been considered as specific dysfunctions of neuronal functions. Studies of the recent decade, however, have challenged this simplistic view, highlighting the important role played by neuroglial cells in the onset and/or progression of neuropsychiatric diseases. In the central nervous system (CNS) non-excitable neuroglia are represented by cells of ectodermal origin (astrocytes, mainly responsible for CNS homeostasis and oligodendrocytes that provide myelination and support for axons) and mesodermal origin (microglial cells that are scions of foetal macrophages entering the neural tube early in development; these cells provide for CNS defence and contribute to shaping neuronal networks). Pathological changes of neuroglia are complex; these changes are classified into reactive gliosis (astrogliosis, activation of microglia and hypertrophy of oligodendroglial precursors), gliodegeneration with loss of function and glial pathological remodelling. Combination of these processes defines the evolution of neurological diseases in general and neuropsychiatric disorders in particular. In this research topic we addressed the contribution of neuroglia to major neuropsychiatric pathologies including major depression, schizophrenia, and addictive disorders.

Neuroglia In Neurologic And Psychiatric Disorders Part Ii

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Author :
language : en
Publisher: Elsevier
Release Date : 2025-03-28

Neuroglia In Neurologic And Psychiatric Disorders Part Ii written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-28 with Medical categories.

Neuroglia in Neurologic and Psychiatric Disorders, Part II discusses glia relative to neurologic and psychiatric disorders, emphasizing cross-disease-glial cell dysfunctions. Driven by advances in genetics, transcriptomics, electrophysiologic and imaging techniques, as well as by the increase in knowledge on neuropathologic features and underlying disease mechanisms, this book bridges the gap between neuroglia basic science and neuroglia clinical research. - Provides an overview of neuroglia biology - Identifies neuroglia dysfunction in neurologic and psychiatric disorders - Covers ALS, dementia, Alzheimer, Parkinson, Huntington diseases and more - Includes TBI, Stroke, COVID - Encompasses disorders of mood, eating, sleep, anxiety, schizophrenia, autism, and more

Molecular Mechanisms Of Glia In Development And Disease

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Author : Ryan B. MacDonald
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-11

Molecular Mechanisms Of Glia In Development And Disease written by Ryan B. MacDonald and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-11 with Science categories.

Central Nervous System Acting Drugs Molecular Mechanisms Of Neuroprotection And Neurodegeneration

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Author : Nesrine Salah El Dine El Sayed
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-14

Central Nervous System Acting Drugs Molecular Mechanisms Of Neuroprotection And Neurodegeneration written by Nesrine Salah El Dine El Sayed and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-14 with Science categories.

Glial And Neural Stem Cells As New Therapeutic Targets For Neurodegenerative Disorders

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Author : Sara Xapelli
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-08

Glial And Neural Stem Cells As New Therapeutic Targets For Neurodegenerative Disorders written by Sara Xapelli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-08 with categories.

Biomedical Index To Phs Supported Research

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Author :
language : en
Publisher:
Release Date : 1993

Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.

Biomedical Index To Phs Supported Research Pt A Subject Access A H

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Author :
language : en
Publisher:
Release Date : 1992

Biomedical Index To Phs Supported Research Pt A Subject Access A H written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medicine categories.

Minding Glial Cells In The Novel Understandings Of Mental Illness

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Author : Takahiro A. Kato
language : en
Publisher: Frontiers Media SA
Release Date : 2017-05-03

Minding Glial Cells In The Novel Understandings Of Mental Illness written by Takahiro A. Kato and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-03 with categories.

Traditionally, abnormalities of neurons and neuronal networks including synaptic abnormalities and disturbance of neurotransmitters have dominantly been believed to be the main causes of psychiatric disorders. Recent cellular neuroscience has revealed various unknown roles of glial cells such as astrocytes, oligodendrocytes and microglia. These glial cells have proved to continuously contact with neurons /synapses, and have been shown to play important roles in brain development, homeostasis and various brain functions. Beyond the classic neuronal doctrine, accumulating evidence has suggested that abnormalities and disturbances of neuron-glia crosstalk may induce psychiatric disorders, while these mechanisms have not been well understood. This Research Topic of the Frontiers in Cellular Neuroscience will focus on the most recent developments and ideas in the study of glial cells (astrocytes, oligodendrocytes and microglia) focusing on psychiatric disorders such as schizophrenia, mood disorders and autism. Not only molecular, cellular and pharmacological approaches using in vitro / in vivo experimental methods but also translational research approaches are welcome. Novel translational research approaches, for example, using novel techniques such as induced pluripotent stem (iPS) cells, may lead to novel solutions. We believe that investigations to clarify the correlation between glial cells and psychiatric disorders contribute to a novel understanding of the pathophysiology of these disorders and the development of effective treatment strategies.

Neuroglia In The Healthy Nervous System Part I

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Author :
language : en
Publisher: Elsevier
Release Date : 2025-03-22

Neuroglia In The Healthy Nervous System Part I written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-22 with Medical categories.

Neuroglia in the Healthy Nervous System, Part I provides insights into newly emerging developments in neuroglia biology, focusing on the healthy nervous system. Driven by advances in genetics, transcriptomics, electrophysiological, and imaging techniques, this volume bridges the gap between neuroglia basic science and neuroglia clinical research. The book provides an overview of neuroglia biology, highlighting emerging technologies used to unravel the role of neuroglial cells in specific brain functions. The book also discusses strategies using neuroglia as a therapeutic target. - Provides an overview of neuroglia biology - Identifies normal neuroglia function in the healthy nervous system - Includes animal and human research - Discusses transcriptomic, electrophysiological, and imaging techniques to study neuroglia - Covers research using neuroglia as a therapeutic target

Glial Cell Line Derived Neurotrophic Factors Advances In Research And Application 2012 Edition

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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26

Glial Cell Line Derived Neurotrophic Factors Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.

Glial Cell Line-Derived Neurotrophic Factors—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Glial Cell Line-Derived Neurotrophic Fa in a concise format. The editors have built Glial Cell Line-Derived Neurotrophic Factors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Glial Cell Line-Derived Neurotrophic Fa in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Glial Cell Line-Derived Neurotrophic Factors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.