Glial And Neural Stem Cells As New Therapeutic Targets For Neurodegenerative Disorders

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Glial And Neural Stem Cells As New Therapeutic Targets For Neurodegenerative Disorders

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Author : Sara Xapelli
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-08

Glial And Neural Stem Cells As New Therapeutic Targets For Neurodegenerative Disorders written by Sara Xapelli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-08 with categories.

Gene Therapy Of The Central Nervous System From Bench To Bedside

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Author : Michael G. Kaplitt
language : en
Publisher: Gulf Professional Publishing
Release Date : 2006

Gene Therapy Of The Central Nervous System From Bench To Bedside written by Michael G. Kaplitt and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.

Few areas of biomedical research provide greater opportunities to capitalize upon the revolution in genomics and molecular biology than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy in the Brain: From Bench to Bedside represents the definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped to create the field as well as those who are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects which would be of interest to anyone who is currently using or contemplating exploring gene therapy for neurobiological applications. Basic gene transfer technologies are discussed, with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells. Numerous research applications are reviewed, particularly in complex fields such as behavioral neurobiology. Several preclinical areas are also covered which are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis. Among the most exciting advances in recent years has been the use of neurological gene therapy in human clinical trials, including Parkinson's disease, Canavan disease and Batten disease. Finally, readers will find "insider" information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use. This work provides up-to-date information and key insights into those gene therapy issues which are important to both scientists and clinicians focusing upon the brain and central nervous system.

International Review Of Cytology

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Author : Kwang W. Jeon
language : en
Publisher: Elsevier
Release Date : 2011-09-02

International Review Of Cytology written by Kwang W. Jeon and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-02 with Science categories.

International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Translational Stem Cell Research

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Author : Kristina Hug
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-25

Translational Stem Cell Research written by Kristina Hug and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-25 with Science categories.

For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.

Role Of Glial Cells Of The Central And Peripheral Nervous System In The Pathogenesis Of Neurodegenerative Disorders

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Author : Guanghui Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-26

Role Of Glial Cells Of The Central And Peripheral Nervous System In The Pathogenesis Of Neurodegenerative Disorders written by Guanghui Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-26 with Science categories.

Neuroglia In Neurodegenerative Diseases

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Author : Alexei Verkhratsky
language : en
Publisher: Springer Nature
Release Date : 2019-10-03

Neuroglia In Neurodegenerative Diseases written by Alexei Verkhratsky and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-03 with Medical categories.

This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative process, and as such are essential players in a variety of diseases, including Alzheimer’s, Parkinson’s, and Huntington’s. Intended for researchers and students, the book presents recent advances concerning the biology of neuroglia as well as their interaction with neurons during disease progression. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.

Modulating Glial Cells Phenotype New Findings And Therapies

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Author : Alberto Javier Ramos
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-21

Modulating Glial Cells Phenotype New Findings And Therapies written by Alberto Javier Ramos and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-21 with Science categories.

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Stem Cell Based Therapy For Neurodegenerative Diseases

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Author : Fabin Han
language : en
Publisher: Springer Nature
Release Date : 2020-10-26

Stem Cell Based Therapy For Neurodegenerative Diseases written by Fabin Han and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-26 with Science categories.

This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.

Novel Therapeutic Target And Drug Discovery For Neurological Diseases

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Author : Rui Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-14

Novel Therapeutic Target And Drug Discovery For Neurological Diseases written by Rui Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-14 with Science categories.

Nanotechnologies In Neuroscience And Neuroengineering

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Author : Ioan Opris
language : en
Publisher: Frontiers Media SA
Release Date : 2020-05-05

Nanotechnologies In Neuroscience And Neuroengineering written by Ioan Opris and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-05 with categories.