Modulating Glial Cells Phenotype New Findings And Therapies
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Modulating Glial Cells Phenotype New Findings And Therapies
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Author : Alberto Javier Ramos
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-21
Modulating Glial Cells Phenotype New Findings And Therapies written by Alberto Javier Ramos and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-21 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Enteric Glia
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Author : Brian D. Gulbransen
language : en
Publisher: Biota Publishing
Release Date : 2014-07-01
Enteric Glia written by Brian D. Gulbransen and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Medical categories.
The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography
Translational Pain Research
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Author : Lawrence Kruger
language : en
Publisher: CRC Press
Release Date : 2009-11-24
Translational Pain Research written by Lawrence Kruger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-24 with Health & Fitness categories.
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical
Glial And Neural Stem Cells As New Therapeutic Targets For Neurodegenerative Disorders
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Author : Sara Xapelli
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-08
Glial And Neural Stem Cells As New Therapeutic Targets For Neurodegenerative Disorders written by Sara Xapelli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-08 with categories.
Spinal Muscular Atrophy
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Author : Charlotte J Sumner
language : en
Publisher: Academic Press
Release Date : 2016-10-24
Spinal Muscular Atrophy written by Charlotte J Sumner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-24 with Medical categories.
Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA Includes outstanding questions and perspectives for future investigations and key references for additional detailed study
Cannabinoids As Potential Treatment For Neurological Diseases
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Author : María Gómez-Cañas
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-30
Cannabinoids As Potential Treatment For Neurological Diseases written by María Gómez-Cañas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-30 with Science categories.
Advances In Cell And Gene Therapy In Treating Neural Diseases
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Author : Raymond Ching-Bong Wong
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-07
Advances In Cell And Gene Therapy In Treating Neural Diseases written by Raymond Ching-Bong Wong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-07 with Science categories.
Glial Cells Maladaptive Plasticity And Neurodegeneration Mechanisms Targeted Therapies And Future Directions
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Author : Giovanni Cirillo
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-17
Glial Cells Maladaptive Plasticity And Neurodegeneration Mechanisms Targeted Therapies And Future Directions written by Giovanni Cirillo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-17 with Science categories.
Microglial Polarization In The Pathogenesis And Therapeutics Of Neurodegenerative Diseases
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Author : Yu Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2018
Microglial Polarization In The Pathogenesis And Therapeutics Of Neurodegenerative Diseases written by Yu Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Microglia-mediated neuroinflammation is one of the shared prominent hallmarks among various forms of neurodegeneration. Depending on the milieu in which microglia become activated, the polarization of microglia shows to be heterogeneous with diverse functional phenotypes that range from pro-inflammatory phenotypes to immunosuppressive phenotypes. Therefore, targeting microglial polarization holds great promise for the treatment of neurodegeneration. This eBook focuses on the potential mechanisms of microglial polarization that are critically associated with a broad spectrum of neurodegenerative diseases, including Parkinson’s disease (PD), Alzheimer’s disease (AD), Amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), Traumatic brain injury (TBI), glaucomatous neurodegeneration and prion diseases. This topic also involves the therapeutic targeting of microglial polarization by nutritional and pharmacological modulators. Moreover, this topic describes advanced technologies employed for studying microglia. Age-related changes in microglia functions are also discussed. Overall, this eBook provides comprehensive understandings of microglial polarization in the course of neurodegeneration, linking with aging-related microglial alterations and technologies developed for microglial studies. Hopefully, it will also give comprehensive insights into various aspects of therapeutic treatment for neurodegeneration, through targeting microglial polarization.
Molecular And Cell Biology Of Pain
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-03-02
Molecular And Cell Biology Of Pain written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-02 with Science categories.
Pain is the number one reason that people seek medical attention but pain is still under- and poorly-treated world-wide. The purpose of this book is to give an up to date picture of what causes pain, how pain becomes chronic and what pharmacological targets might be manipulated to alleviate acute and chronic pain. The book will cover a wide array of topics from gene polymorphisms to voltage-gated ion channels moving from cellular biology to whole animal physiology. Written by future leaders in the pain field Covers a wide range of targets Contains provocative ideas about the future direction of the pain field.