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Strategies And Tools For Modulating Pathologic Protein Self Assembly In Proteinopathies


Strategies And Tools For Modulating Pathologic Protein Self Assembly In Proteinopathies
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Strategies And Tools For Modulating Pathologic Protein Self Assembly In Proteinopathies


Strategies And Tools For Modulating Pathologic Protein Self Assembly In Proteinopathies
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Author : Gal Bitan
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-16

Strategies And Tools For Modulating Pathologic Protein Self Assembly In Proteinopathies written by Gal Bitan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-16 with Science categories.




Early Stage Protein Misfolding And Amyloid Aggregation


Early Stage Protein Misfolding And Amyloid Aggregation
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-01-30

Early Stage Protein Misfolding And Amyloid Aggregation written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-30 with Science categories.


Early Stage Protein Misfolding and Amyloid Aggregation, Volume 329, the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology, including articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership and maintains a high standard by publishing invited articles on important and timely topics as authored by prominent cell and molecular biologists.



Tau Biology


Tau Biology
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Author : Akihiko Takashima
language : en
Publisher: Springer
Release Date : 2020-02-25

Tau Biology written by Akihiko Takashima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-25 with Medical categories.


This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death. With the help of new technologies, researchers are now solving these long-standing questions. In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.



Bioinorganic Chemistry Of Copper


Bioinorganic Chemistry Of Copper
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Author : K.D. Karlin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bioinorganic Chemistry Of Copper written by K.D. Karlin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Bioinorganic Chemistry of Copper focuses on the vital role of copper ions in biology, especially as an essential metalloenzyme cofactor. The book is highly interdisciplinary in its approach--the outstanding list of contributors includes coordination chemists, biochemists, biophysicists, and molecular biologists. Chapters are grouped into major areas of research interest in inorganic copper chemistry, spectroscopy, oxygen chemistry, biochemistry, and molecular biology. The book also discusses basic research of great potential importance to pharmaceutical scientists. This book is based on the first Johns Hopkins University Copper Symposium, held in August 1992. Researchers in chemistry, biochemistry, molecular biology, and medicinal chemistry will find it to be an essential reference on its subject.



Heparin A Century Of Progress


Heparin A Century Of Progress
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Author : Rebecca Lever
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-05-08

Heparin A Century Of Progress written by Rebecca Lever and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-08 with Medical categories.


Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.



The Ubiquitin System


The Ubiquitin System
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Author : Milton J. Schlesinger
language : en
Publisher: Cold Spring Harbor Laboratory Press
Release Date : 1988

The Ubiquitin System written by Milton J. Schlesinger and has been published by Cold Spring Harbor Laboratory Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.




The Big Book On Small Heat Shock Proteins


The Big Book On Small Heat Shock Proteins
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Author : Robert M. Tanguay
language : en
Publisher: Springer
Release Date : 2015-06-15

The Big Book On Small Heat Shock Proteins written by Robert M. Tanguay and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-15 with Medical categories.


Based upon a workshop entitled “The Small HSP World” held in Québec 2-5 October 2014. Twenty-five scientists provided chapters for the book. The chapters are from the best scientists currently working in this field. These colleagues include Arrigo, Benesch, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Hightower, Kampinga, Lavoie, MacRae, Quinlan, Tanguay, Vierling, Vigh, Weeks and Wu. Briefly, the book starts with the structure of small heat shock proteins, moving to their functions and finishing with their involvement in diseases. Although this is quite broad, the structural aspect will be the unifying theme of the book.



Protein Self Assembly


Protein Self Assembly
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Author : Jennifer J. McManus
language : en
Publisher: Humana
Release Date : 2020-08-08

Protein Self Assembly written by Jennifer J. McManus and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-08 with Science categories.


This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.



Methods For Study And Manipulation Of Protein Self Assembly


Methods For Study And Manipulation Of Protein Self Assembly
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Author : Lisa Hecker
language : en
Publisher:
Release Date : 2021

Methods For Study And Manipulation Of Protein Self Assembly written by Lisa Hecker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.