Role Of Glial Cells Of The Central And Peripheral Nervous System In The Pathogenesis Of Neurodegenerative Disorders
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Role Of Glial Cells Of The Central And Peripheral Nervous System In The Pathogenesis Of Neurodegenerative Disorders
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Author : Guanghui Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-26
Role Of Glial Cells Of The Central And Peripheral Nervous System In The Pathogenesis Of Neurodegenerative Disorders written by Guanghui Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-26 with Science categories.
Peripheral Immune System And Neurodegenerative Disease
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Author : Ke Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-15
Peripheral Immune System And Neurodegenerative Disease written by Ke Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-15 with Science categories.
Physiology And Function Of Glial Cells In Health And Disease
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Author : El-Mansoury, Bilal
language : en
Publisher: IGI Global
Release Date : 2023-12-18
Physiology And Function Of Glial Cells In Health And Disease written by El-Mansoury, Bilal and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-18 with Science categories.
Glial cells, including microglia, astrocytes, oligodendrocytes, and their progenitors NG2-glia, serve as key players in maintaining structural integrity and complex brain homeostasis. They actively participate in neurotransmission, energy metabolism, synaptic plasticity, neurogenesis, ion balance, immune defense, and the clearance of neuronal debris. However, the physiological functions of glial cells are often compromised in aging, neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, and multiple sclerosis, as well as in gliomas, brain tumors demanding specialized understanding for effective therapeutic interventions. Physiology and Function of Glial Cells in Health and Disease provides a comprehensive exploration of the vital role played by glial cells in maintaining neural homeostasis within the central nervous system (CNS). This book delves into the intricate interaction between glial cells and neurons, shedding light on their essential contributions to neural function and overall brain health. The book also highlights emerging research on astrocyte reprogramming for the management of neurodegenerative diseases, offering a glimpse into potential future therapies. This book is an essential resource for researchers, clinicians, and students in the field of neuroscience. Its academic tone, coupled with in-depth discussions and cutting-edge insights, makes it a valuable reference for anyone seeking a comprehensive understanding of the role of glial cells in both health and disease.
Enteric Glia
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Author : Brian D. Gulbransen
language : en
Publisher: Biota Publishing
Release Date : 2014-07-01
Enteric Glia written by Brian D. Gulbransen and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Medical categories.
The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography
Glial Physiology And Pathophysiology
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Author : Alexei Verkhratsky
language : en
Publisher: John Wiley & Sons
Release Date : 2013-01-31
Glial Physiology And Pathophysiology written by Alexei Verkhratsky and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-31 with Medical categories.
Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides
Understanding The Roles Of Glia And Circulating Leukocytes In Neurodegenerative Diseases
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Author : Tuan Leng Tay
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-03
Understanding The Roles Of Glia And Circulating Leukocytes In Neurodegenerative Diseases written by Tuan Leng Tay and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-03 with Medical categories.
Microglial Polarization In The Pathogenesis And Therapeutics Of Neurodegenerative Diseases
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Author : Yu Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2018
Microglial Polarization In The Pathogenesis And Therapeutics Of Neurodegenerative Diseases written by Yu Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Microglia-mediated neuroinflammation is one of the shared prominent hallmarks among various forms of neurodegeneration. Depending on the milieu in which microglia become activated, the polarization of microglia shows to be heterogeneous with diverse functional phenotypes that range from pro-inflammatory phenotypes to immunosuppressive phenotypes. Therefore, targeting microglial polarization holds great promise for the treatment of neurodegeneration. This eBook focuses on the potential mechanisms of microglial polarization that are critically associated with a broad spectrum of neurodegenerative diseases, including Parkinson’s disease (PD), Alzheimer’s disease (AD), Amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), Traumatic brain injury (TBI), glaucomatous neurodegeneration and prion diseases. This topic also involves the therapeutic targeting of microglial polarization by nutritional and pharmacological modulators. Moreover, this topic describes advanced technologies employed for studying microglia. Age-related changes in microglia functions are also discussed. Overall, this eBook provides comprehensive understandings of microglial polarization in the course of neurodegeneration, linking with aging-related microglial alterations and technologies developed for microglial studies. Hopefully, it will also give comprehensive insights into various aspects of therapeutic treatment for neurodegeneration, through targeting microglial polarization.
Nanomaterials For Drug Delivery And Neurological Diseases Management
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Author : Santosh Kumar Rath
language : en
Publisher: Springer Nature
Release Date : 2024-06-25
Nanomaterials For Drug Delivery And Neurological Diseases Management written by Santosh Kumar Rath and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-25 with Technology & Engineering categories.
This book gives a complete overview of current developments in the nano drug delivery technology in the management of neurological disorders and brain diseases. The book is divided into three main sub-sections: A) Fundamental study on nanomaterials, nanocarriers, and nanoformulation-based drug delivery in neurological diseases management, B) Nano drug delivery therapy - a novel approach towards common neurological disorders and C) Novel nano delivery strategies in targeted neurological diseases management. This collective work presents diverse nano-based drug delivery technologies that are high-throughput, reliable, pioneering, and applicable to researchers of different countries despite their socio-economic conditions. It hopefully encourages researchers, innovators and policymaker to adapt nanomaterial-based drug delivery vehicles technologies using diverse nano-based formulation techniques as targeted therapy for treating and managing neurological disorders.
Neuroglia In Neurologic And Psychiatric Disorders Part Ii
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Author :
language : en
Publisher: Elsevier
Release Date : 2025-03-28
Neuroglia In Neurologic And Psychiatric Disorders Part Ii written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-28 with Medical categories.
Neuroglia in Neurologic and Psychiatric Disorders, Part II discusses glia relative to neurologic and psychiatric disorders, emphasizing cross-disease-glial cell dysfunctions. Driven by advances in genetics, transcriptomics, electrophysiologic and imaging techniques, as well as by the increase in knowledge on neuropathologic features and underlying disease mechanisms, this book bridges the gap between neuroglia basic science and neuroglia clinical research. - Provides an overview of neuroglia biology - Identifies neuroglia dysfunction in neurologic and psychiatric disorders - Covers ALS, dementia, Alzheimer, Parkinson, Huntington diseases and more - Includes TBI, Stroke, COVID - Encompasses disorders of mood, eating, sleep, anxiety, schizophrenia, autism, and more
Pioneering Biomedical Breakthroughs Advanced Multidisciplinary Research In Neurological Disorders Renal Diseases And Postpartum Health Through Technology And Innovation
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Author : Mahesh Recharla
language : en
Publisher: Deep Science Publishing
Release Date : 2025-06-06
Pioneering Biomedical Breakthroughs Advanced Multidisciplinary Research In Neurological Disorders Renal Diseases And Postpartum Health Through Technology And Innovation written by Mahesh Recharla and has been published by Deep Science Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-06 with Technology & Engineering categories.
In the quest to decode the complexities of human health, the intersection of biomedical science, technology, and multidisciplinary collaboration has become more crucial than ever. Pioneering Biomedical Breakthroughs: Advanced Multidisciplinary Research in Neurological Disorders, Renal Diseases, and Postpartum Health through Technology and Innovation brings together transformative insights and research that are redefining how we understand, diagnose, and treat some of the most challenging medical conditions of our time. This book emerges from a growing recognition that solving deeply rooted healthcare issues—such as Alzheimer’s disease, chronic kidney conditions, and postpartum complications—requires a convergence of expertise across neurology, nephrology, maternal health, genomics, data science, and engineering. It highlights the pioneering work being done across these domains, driven by advances in artificial intelligence, wearable biosensors, molecular diagnostics, and personalized treatment models. Through a multidisciplinary lens, this book explores how technological innovation is accelerating early detection, improving patient outcomes, and paving the way for more targeted and compassionate care. From brain-computer interfaces and AI-powered imaging for neurological disorders, to smart dialysis systems for renal health, and predictive models for postpartum depression, each chapter showcases research that is pushing the boundaries of traditional healthcare. This work is intended for researchers, clinicians, bioengineers, students, and innovators who are passionate about shaping the future of medicine through collaboration and cutting-edge science. It not only captures the state-of-the-art technologies being deployed but also addresses the ethical, clinical, and societal considerations that must guide responsible innovation. We hope this book serves as both a resource and a catalyst—for sparking new ideas, inspiring cross-disciplinary partnerships, and ultimately contributing to a world where precision care and technological equity become the norm, not the exception.