Understanding The Roles Of Glia And Circulating Leukocytes In Neurodegenerative Diseases
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Understanding The Roles Of Glia And Circulating Leukocytes In Neurodegenerative Diseases
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Author : Tuan Leng Tay
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-03
Understanding The Roles Of Glia And Circulating Leukocytes In Neurodegenerative Diseases written by Tuan Leng Tay and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-03 with Medical categories.
Glia In Health And Disease
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Author : Tania Spohr
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-05-20
Glia In Health And Disease written by Tania Spohr and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-20 with Science categories.
The book will highlight the role played by glial cells in the central and peripheral nervous systems in both healthy and unhealthy individuals. Among all processes involved, we will discuss the importance of the enteric nervous system in the control of gut homeostasis, in the interaction with the immune system, and its participation in pathological conditions such as metabolic syndrome. We will also look at the relevance of astrocytes during synaptic transmission and the regulation of plasticity by releasing gliotransmitters. Ultimately, we will highlight the influence of astrocytes during the development of a number of neurodegenerative diseases, such as multiple sclerosis and Alzheimer’s disease, focusing on how the serum levels of the astrocytic protein S100B can be used as a biomarker for clinical decisions.
Glia And Inflammation In Neurodegenerative Disease
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Author : M. A. Yenari
language : en
Publisher: Nova Science Publishers
Release Date : 2006
Glia And Inflammation In Neurodegenerative Disease written by M. A. Yenari and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
The brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within the brain parenchyma. Microglia have long been thought to be the brain's resident immune cell with myeloid lineage similar to monocytes and macrophages. In this volume, the authors review the current state of knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. The changing role of inflammation with development is considered. They also present a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.
Common Pathways Linking Neurodegenerative Diseases The Role Of Inflammation
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Author : Grzegorz Kreiner
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-01
Common Pathways Linking Neurodegenerative Diseases The Role Of Inflammation written by Grzegorz Kreiner and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-01 with Science categories.
Cns Injuries
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Author : Martin Berry
language : en
Publisher: CRC Press
Release Date : 2019-09-17
Cns Injuries written by Martin Berry and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-17 with Medical categories.
The basic science of the cellular and molecular responses of the brain to injury is a rapidly expanding area of research that provides evidence of growing opportunities for pharmacological intervention in the clinic. CNS Injuries: Cellular Responses and Pharmacological Strategies is an examination of developments in our understanding of the cellular and trophic responses to CNS injuries and the potential treatment. This text collates reviews of the most important areas of study regarding injury response including inflammatory and immune reactions scarring neuron death demyelination and remyelination axonal regeneration re-establishment of neuronal connectivity Providing a record of recent advances that will help point the way to future developments, this enlightening reference is sure to benefit researchers and practitioners in a broad range of disciplines, including: neurology, pharmacology, pathology, toxicology, immunology, and many others.
The Hypothalamus Pituitary Adrenal Axis
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Author :
language : en
Publisher: Elsevier
Release Date : 2008-09-12
The Hypothalamus Pituitary Adrenal Axis written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-12 with Science categories.
The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. - Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle - Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later
Vascular Inflammation In Aging And Neurodegeneration
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Author : Donghui Zhu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-16
Vascular Inflammation In Aging And Neurodegeneration written by Donghui Zhu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-16 with Science categories.
Psychological Frailty In Ageing Lifespan Trajectories And Emerging Risks
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Author : Esperanza Navarro-Pardo
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-21
Psychological Frailty In Ageing Lifespan Trajectories And Emerging Risks written by Esperanza Navarro-Pardo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-21 with Science categories.
Targeting Neuroinflammation For Novel Therapeutics In Neurodegenerative Diseases
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Author : Pukar Khanal
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-02
Targeting Neuroinflammation For Novel Therapeutics In Neurodegenerative Diseases written by Pukar Khanal and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-02 with Science categories.
Neurodegenerative disorders have increasing incidence with limited treatment options. Approaches to target neuroinflammation in various neurodegenerative disorders, such as Alzheimer’s disease (AD), involve a quest for innovative therapeutics. A comprehensive understanding of the quest for small compounds that improve amyloid processing, regulate autophagy, hinder Aß accumulation, and investigate the array of phytochemicals present in naturally occurring nootropics (ethnomedicines) and polypharmacology may facilitate the exploration of diverse pharmacological approaches to impede disease advancement. Galantamine from snowdrops (Galanthus spp.) is just one example of a current core medication used in the management of cognitive decline, pointing to the potential of small molecules in this context. In addition, the combinations of computational and experimental pharmacological methods enable the exploration of small molecules within crucial neurodegenerative processes, which can help to develop potential therapeutic compounds.
Glial Physiology And Pathophysiology
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Author : Alexei Verkhratsky
language : en
Publisher: John Wiley & Sons
Release Date : 2013-04-15
Glial Physiology And Pathophysiology written by Alexei Verkhratsky and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-15 with Medical categories.
Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverage includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role of glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides