Neurohumoral Regulation Of Coronary Flow
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Neurohumoral Regulation Of Coronary Flow
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Author : W. H. (Wiek) van Gilst
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Neurohumoral Regulation Of Coronary Flow written by W. H. (Wiek) van Gilst and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
During the last decade we have witnessed a rapid expansion of our knowledge of the role of the endothelium in the control of vascular tone and hemostasis. In paricular, developments in molecular biology have enabled us to understand its physiology in greater detail. Furthermore, it is now clear that dysfunction of the endothelium contributes to various cardiovascular diseases. This is especially true for the coronary vascular bed. Development of atherosclerosis, disturbed vasomotor tone in stable ischemic syndromes, and the interaction of thrombocytes with the endothelium in acute ischemic syndrome are all consequences of endothelium dysfunction. Also, secondary changes in endothelial function have been described, for instance in chronic heart failure. This monograph reviews the present knowledge of the role of the endothelium in the control of coronary flow. The authors lead the reader through this topic starting at the basic physiology of endothelial function and the principles of coronary flow regulation. Next, the use of modern clinical techniques to evaluate endothelial function such as positron emission tomography and angioscopy are discussed. Subsequently, several pathophysiological processes and the role of endothelium are addressed. Finally, the interaction of various presently used cardiovascular drugs with the endothelium is indicated. It is the combination of basic sciences with clinical observations in this book which may be appreciated by a large number of scientists and physicians active in the field of cardiovascular disease. It is also this combination of different disciplines which will determine future developments and new avenues in pharmacotherapy involving the endothelium.
Coronary Circulation
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Author : Johnathan D. Tune
language : en
Publisher: Biota Publishing
Release Date : 2014-07-01
Coronary Circulation written by Johnathan D. Tune and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Medical categories.
The coronary circulation is unique in that it is responsible for maintaining adequate oxygen and substrate delivery to the organ that generates the pressure needed to drive blood throughout the entire circulatory system. In the simplest terms, coronary blood flow is directly proportional to the arterial pressure gradient across the coronary vasculature and inversely proportional to coronary vascular resistance. However, myocardial perfusion is collectively regulated by a complex variety of mechanisms which include: (1) extravascular compressive forces; (2) diastolic time fraction; (3) coronary perfusion pressure; (4) myocardial metabolism (local metabolic factors); (5) endothelial-derived substances; (6) neuro-humoral influences; and (7) arterial oxygen tension and content. This book considers each of these determinants with particular emphasis on the functional interaction between the physical and biological determinants of myocardial perfusion. Pathophysiologic aspects of coronary atherosclerosis and cardiovascular disease states are also considered. Table of Contents: Abbreviations / Acknowledgments / Introduction / Basic Coronary Anatomy / Myocardial-Coronary Interaction / Arterial Pressure and Autoregulation / Local Metabolic Control / Endothelial-Dependent Control / Neural Activation and Circulating Hormones / Coronary Stenosis, Myocardial Ischemia, and Effects of Disease / Summary / Reference List / Author Biography
Regulation Of Coronary Blood Flow
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Author : Michitoshi Inoue
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09
Regulation Of Coronary Blood Flow written by Michitoshi Inoue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Regulation Of Coronary Blood Flow
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Author : Michitoshi Inoue
language : en
Publisher: Springer Verlag
Release Date : 1991
Regulation Of Coronary Blood Flow written by Michitoshi Inoue and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
Coronary Blood Flow
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Author : J.A. Spaan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coronary Blood Flow written by J.A. Spaan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
by JULIEN IE HOFFMAN One of the earliest coronary physiologists was Scaramucci who, in 1695, postu lated that during systole the contracting myocardium inhibited coronary blood flow. Since then, the many contributions that have been made to our knowledge of the coronary circulation can be arbitrarily divided into three phases based on advances in technical methods. The early phase of research into the coronary circulation, done with great difficulty with crude methods, may be regarded as ending in the 1940s, and it included major discoveries made by such well known investigators as Georg von Anrep, Ernest Starling, Carl Wiggers, and Louis Katz, who formulated much of our basic understanding of the field. After 1940, the field of coronary physiology entered a new phase when instruments for high fidelity registration of coronary flow and pressure became available. This era was domi nated by Donald Gregg who combined careful attention to the function of these instruments (some of which he helped to develop) with an extraordinary ability to discern mechanisms from apparently minor changes in coronary flow and pressure patterns. His book 'The Coronary Circulation in Health and Disease' set a new standard in the field. After 1960, techniques for measuring regional myocardial blood flow became available, and enabled a large group of eminent investigators to make major advances in understanding the physiology and pathophysiology of myocardial blood flow.
Coronary Blood Flow
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Author : Jos Spaan
language : en
Publisher: Springer
Release Date : 2011-09-30
Coronary Blood Flow written by Jos Spaan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-30 with Medical categories.
by JULIEN IE HOFFMAN One of the earliest coronary physiologists was Scaramucci who, in 1695, postu lated that during systole the contracting myocardium inhibited coronary blood flow. Since then, the many contributions that have been made to our knowledge of the coronary circulation can be arbitrarily divided into three phases based on advances in technical methods. The early phase of research into the coronary circulation, done with great difficulty with crude methods, may be regarded as ending in the 1940s, and it included major discoveries made by such well known investigators as Georg von Anrep, Ernest Starling, Carl Wiggers, and Louis Katz, who formulated much of our basic understanding of the field. After 1940, the field of coronary physiology entered a new phase when instruments for high fidelity registration of coronary flow and pressure became available. This era was domi nated by Donald Gregg who combined careful attention to the function of these instruments (some of which he helped to develop) with an extraordinary ability to discern mechanisms from apparently minor changes in coronary flow and pressure patterns. His book 'The Coronary Circulation in Health and Disease' set a new standard in the field. After 1960, techniques for measuring regional myocardial blood flow became available, and enabled a large group of eminent investigators to make major advances in understanding the physiology and pathophysiology of myocardial blood flow.
Reflex Control Of The Circulation
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Author : Irving H. Zucker
language : en
Publisher: CRC Press
Release Date : 2020-02-03
Reflex Control Of The Circulation written by Irving H. Zucker and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-03 with Medical categories.
Reflex Control of the Circulation presents an interdisciplinary discussion of concepts in the reflex control of circulation. This volume describes aspects of autonomic receptor physiology, central pathways of reflex control, the electrophysiology of cardiovascular afferents, the interaction between reflexes, the autonomic control of regional blood flows, the autonomic control of fluid and electrolyte balance, and neurohumoral control of the circulation through normal and pathological states (e.g., hypertension, congestive heart failure). In addition, the regulation of regional blood flow during exercise and developmental aspects of reflex control are examined. Any researcher interested in the autonomic system and its role in circulation will find this book fascinating reading.
The Coronary Circulation In Health And Disease
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Author : Melvin L. Marcus
language : en
Publisher: McGraw-Hill Companies
Release Date : 1983
The Coronary Circulation In Health And Disease written by Melvin L. Marcus and has been published by McGraw-Hill Companies this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.
Lane Medical Lectures
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Author : Gleb Vasīlʹevīch Anrep
language : en
Publisher: Stanford University Press
Release Date : 1936
Lane Medical Lectures written by Gleb Vasīlʹevīch Anrep and has been published by Stanford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1936 with Blood-vessels categories.
Core Topics In Cardiac Anesthesia
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Author : Jonathan H. Mackay
language : en
Publisher: Cambridge University Press
Release Date : 2012-03-15
Core Topics In Cardiac Anesthesia written by Jonathan H. Mackay and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-15 with Medical categories.
Since the publication of the first edition of Core Topics in Cardiac Anaesthesia, the clinical landscape has undergone significant change. Recent developments include the increased use of electrophysiology, the resurgence of primary percutaneous intervention in acute coronary syndromes, the use of percutaneous devices in patients previously considered inoperable, and the withdrawal of aprotinin. Against this landscape, this invaluable resource has been fully updated. New chapters are dedicated to right heart valves, pulmonary vascular disease, cardiac tumours and cardiac trauma. All other chapters have been updated according to the latest international guidelines. Written and edited by an international author team with a wealth of expertise in all aspects of the perioperative care of cardiac patients, topics are presented in an easy to digest and a readily accessible manner. Core Topics in Cardiac Anaesthesia, Second Edition is essential reading for residents and fellows in anaesthesia and cardiac surgery and clinical perfusionists.