Neuroinflammation In Alzheimer S Disease
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Neuroinflammatory Mechanisms In Alzheimer S Disease
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Author : Joseph Rogers
language : en
Publisher: Birkhäuser
Release Date : 2013-03-11
Neuroinflammatory Mechanisms In Alzheimer S Disease written by Joseph Rogers and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-11 with Medical categories.
Research into inflammatory mechanisms that may cause damage to the Alzheimer's disease (AD) brain has now been ongoing for nearly two decades. Some two dozen clinical studies have strongly suggested that conventional anti-inflammatory drugs may be useful to delay the onset or slow the progression of the disorder. Moreover, virtually all the major systems of the innate immune response appear to be present, and most are upregulated, in pathologically-vulnerable regions of the AD brain. These new findings are described in this volume - first in overview form, followed by chapters on topics of special interest. In many ways, to understand AD brain inflammation, one need only review a text on peripheral inflammation biology, leaving out the chapters on humoral medi ators and substituting microglia for macrophages. In several other key respects, however, AD brain inflammation is unique, due primarily to idiosyncratic interac tions of inflammatory mediators and mechanisms with classical AD pathology: amyloid ~ peptide(A~) deposits and neurofibrillary tangles (NFTs). For this reason, some key concepts about the inflammation that occurs in AD may warrant discus sion in preparation for the more detailed chapters that follow.
Neuroinflammation From Bench To Bedside
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Author : H. Kettenmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Neuroinflammation From Bench To Bedside written by H. Kettenmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.
Recent work has implicated inflammatory processes in the pathophysiology of a variety of neurodegenerative diseases such as Alzheimer's disease, stroke and multiple sclerosis. In this book leading experts in the field discuss molecular, in vivo and clinical aspects of neuroinflammation. It is hoped, with the wealth of research being conductied in this area, that novel therapeutic targets will be identified which will allow successful therapeutic intervention in a variety of neurodegenerative diseases.
Neuroinflammation And Its Resolution From Molecular Mechanisms To Therapeutic Perspectives
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Author : Morena Zusso
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-14
Neuroinflammation And Its Resolution From Molecular Mechanisms To Therapeutic Perspectives written by Morena Zusso and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-14 with categories.
Neuroinflammation
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Author : Paul L. Wood
language : en
Publisher: Springer Science & Business Media
Release Date : 1997-10-24
Neuroinflammation written by Paul L. Wood and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-10-24 with Medical categories.
An unprecedented review of our current knowledge of the neuroinflammatory mediators and cells involved in neurodegenerative diseases. Beginning with a detailed review of our current concepts of which biochemical mediators are involved in neuronal loss and the mechanisms of cell death, the distinguished contributors critically examine those areas of current research involved in the design of specific pharmacological agents to inhibit at defined points in the neuroinflammatory cascade. They also address the molecular, cellular, and disease model actions of first-generation agents, as well as the potential clinical relevance to AIDS-related dementia, Alzheimer's disease, amyotropic lateral sclerosis (ALS), Down's syndrome, Huntington's disease, multiple sclerosis, Parkinson's disease, and stroke.
Neuroinflammatory Mechanisms In Alzheimer S Disease
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Author : Joseph Rogers (Ph.D.)
language : en
Publisher: Birkhauser
Release Date : 2001
Neuroinflammatory Mechanisms In Alzheimer S Disease written by Joseph Rogers (Ph.D.) and has been published by Birkhauser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Alzheimer's disease categories.
The Role Of Neuroinflammation In Alzheimer S Disease
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Author : Dimitrios Sideris
language : en
Publisher:
Release Date : 2021
The Role Of Neuroinflammation In Alzheimer S Disease written by Dimitrios Sideris and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Neuroinflammation And Neurodegeneration
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Author : Phillip K. Peterson
language : en
Publisher: Springer
Release Date : 2014-07-08
Neuroinflammation And Neurodegeneration written by Phillip K. Peterson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Medical categories.
State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer’s disease, Parkinson’s disease, stroke, viral encephalitides and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.
Mechanisms Of Neuroinflammation
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Author : Gonzalo Emiliano Aranda Abreu
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-08-23
Mechanisms Of Neuroinflammation written by Gonzalo Emiliano Aranda Abreu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-23 with Medical categories.
"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.
The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome
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Author : Elizabeth Head
language : en
Publisher: Academic Press
Release Date : 2021-08-31
The Neurobiology Of Aging And Alzheimer Disease In Down Syndrome written by Elizabeth Head and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-31 with Medical categories.
The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
Neuroinflammation In Alzheimer S Disease
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Author : Joseph Rogers (Ph. D.)
language : en
Publisher:
Release Date : 2001
Neuroinflammation In Alzheimer S Disease written by Joseph Rogers (Ph. D.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.