Neuromuscular Junctions In Drosophila
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Neuromuscular Junctions In Drosophila
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Author :
language : en
Publisher: Academic Press
Release Date : 1999-04-29
Neuromuscular Junctions In Drosophila written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-04-29 with Science categories.
Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach.This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories.Key Features* Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system* Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function* Written in clear language that is easily understandable to readers not already familiar with fruit fly research* Includes numerous diagrams and extensive reference lists
Exocytosis And Endocytosis
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Author : Andrei I. Ivanov
language : en
Publisher: Springer Science & Business Media
Release Date : 2008
Exocytosis And Endocytosis written by Andrei I. Ivanov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
In this book, skilled experts provide the most up-to-date, step-by-step laboratory protocols for examining molecular machinery and biological functions of exocytosis and endocytosis in vitro and in vivo. The book is insightful to both newcomers and seasoned professionals. It offers a unique and highly practical guide to versatile laboratory tools developed to study various aspects of intracellular vesicle trafficking in simple model systems and living organisms.
The Pharmacology Of Neurogenesis And Neuroenhancement
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Author :
language : en
Publisher: Elsevier
Release Date : 2007-01-02
The Pharmacology Of Neurogenesis And Neuroenhancement written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-02 with Medical categories.
Currently, few drugs are available for the effective treatment of neurodegenerative diseases and neurodevelopmental disorders. Recent advances in neuroscience research offer hope that future strategies for treating these brain disorders will include neurogenesis and neuroenhancement as therapeutic endpoints. This volume reviews cutting-edge findings related to the pharmacological aspects of neurogenesis and neuroprotection. A broad range of topics are covered from basic lab bench research to drug discovery efforts and important clinical issues. This collection of reviews is a perfect way to become acquainted with these exciting new fields in the space of a single volume. Chapters are written with a general audience in mind, but with enough high-level discussion to appeal to specialists and experts as well. The authors have done an excellent job of challenging current paradigms and pushing the boundaries of exploration in keeping with the pioneering spirit that gave rise to these emerging areas of research. Consequently, this will be an indispensable resource for many years to come. - Provides state-of-the-art reviews spanning significant emerging fields - Discusses future directions and questions for future studies - Includes informative illustrations
Muscle Development In Drosophilia
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Author : Helen Sink
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-26
Muscle Development In Drosophilia written by Helen Sink and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-26 with Science categories.
The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations. The book will appeal to those studying muscle development and muscle biology in any organism.
Molecular Mechanisms Of Synaptogenesis
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Author : Alexander Dityatev
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-11-24
Molecular Mechanisms Of Synaptogenesis written by Alexander Dityatev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-24 with Medical categories.
This book provides a new compilation of information that link changes in the basic structure of synapses and brain diseases. The book shows that specific secreted proteins, and short peptide mimicking the function of neural cell adhesion molecules can significantly enhance the formation of synapses in the brain. It describes recent advances in research that lay necessary scientific groundwork to develop pharmacological treatments.
Basic Aspects Of Catechol O Methyltransferase And The Clinical Applications Of Its Inhibitors
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Author :
language : en
Publisher: Academic Press
Release Date : 2010-11-20
Basic Aspects Of Catechol O Methyltransferase And The Clinical Applications Of Its Inhibitors written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-20 with Science categories.
Volume 95 of International Review of Neurobiology focuses on Catechol-O-methyltransferase inhibition, and its clinical application in relation to Parkinson's disease. Chapters cover COMT gene and proteins, L-dopa treatment in Parkinson's disease, the latest research on COMT inhibitors and their clinical applications, as well as future prospects for their use. - Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors - Preclinical models in COMT inhibitor devlopment - Transgenic COMT mice – latest information summarized - Chemistry of COMT inhibitors and their design with molecular modelling - COMT gene and its regulation and relation to dopamine related diseases - Role of cofactor SAM regulation in relation to homocysteine - Nonclinical and clinical safety of COMT inhibitors summarized - Future prospects of COMT inhibitors in Parkinson's disease
Drosophila Protocols
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Author : William Sullivan
language : en
Publisher: CSHL Press
Release Date : 2000
Drosophila Protocols written by William Sullivan and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
This exceptional laboratory manual describes thirty-seven procedures most likely to be used in the next decade for molecular, biochemical, and cellular studies on Drosophila. They were selected after extensive consultation with the research community and rigorously edited for clarity, uniformity, and conciseness.The methods included permit investigation of chromosomes, cell biology, molecular biology, genomes, biochemistry, and development. Each protocol includes the basic information needed by novices, with sufficient detail to be valuable to experienced investigators. Each method is carefully introduced and illustrated with figures, tables, illustrations, and examples of the data obtainable. The book's appendices include key aspects of Drosophila biology, essential solutions, buffers, and recipes.An evolution of Michael Ashburner's 1989 classic Drosophila: A Laboratory Manual, this book is an essential addition to the personal library of Drosophila investigators and an incomparable resource for other research groups with goals likely to require fly-based technical approaches.
Developmental Neurobiology
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Author : Greg Lemke
language : en
Publisher: Academic Press
Release Date : 2010-05-22
Developmental Neurobiology written by Greg Lemke and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-22 with Science categories.
Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbook reference exists on the market that provides researchers with more in-depth, high-level information on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole. This reference is the first of its kind to fill this need. It pulls together the relevant articles on the topic from the 10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and serves as an affordable and immediate resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject. - The first and only comprehensive, single-volume reference for developmental neuroscience that goes beyond the basic textbook information - The 93 chapters cover topics ranging from cell fate determination, path finding, synapse generation, neural stem cells, to neurodegeneration and regeneration, carefully selected from the Encyclopedia of Neuroscience by one of the great developmental neuroscientists, Greg Lemke - The best researchers in the field provide their conclusions in the context of the latest experimental results
The Sticky Synapse
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Author : Michael Hortsch
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-07
The Sticky Synapse written by Michael Hortsch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-07 with Medical categories.
The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive molecules make up a significant portion of the human genome, and neural CAMs even have been postulated to be a major factor in the evolution of the human brain. These are just some of the many reasons why we thought a book on neural CAMs and their role in establishing and maintaining neuronal synapses would be highly appropriate for summarizing our current state of knowledge. Without question, over the near future, additional adhesive proteins will join the ranks of synaptic CAMs and our knowledge, and how these molecules enable neurons and their targets to communicate effectively will grow.
Neurons Methods And Applications For The Cell Biologist
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Author : Peter J. Hollenbeck
language : en
Publisher: Gulf Professional Publishing
Release Date : 2003-07-08
Neurons Methods And Applications For The Cell Biologist written by Peter J. Hollenbeck and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-08 with Medical categories.
Many cell biologists study the properties of cells grown outside of the animal, in the controlled environment of a culture dish. Many cell biologists would benefit from directing their attention to nerve cells, but are afraid to try growing nerve cells in culture because it has the reputation for being much more difficult and unreliable than growing other kinds of cells. This volume is written by cell biologists and neuroscientists who are experts at growing various kinds of neurons in culture and using them for diverse experimental applications. The aim of this volume is to demystify the techniques used to grow nerve cells and to show cell biologists that it is something that they can easily master. * Contains culture methodology for more than a dozen types of CNS and PNS neurons * Includes most recent and reliable techniques from expert practitioners for specific experimental applications * Addresses the latest strategies for transfecting neurons.