Neuronal Polarity Establishment And Maintenance

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Neuronal Polarity Establishment And Maintenance
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Author : Froylan Calderon de Anda
language : en
Publisher: Frontiers Media SA
Release Date : 2018-07-12
Neuronal Polarity Establishment And Maintenance written by Froylan Calderon de Anda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-12 with categories.
The term polarity in a biological context is used to describe an asymmetry in morphology and distribution of molecules. In neurons, their complex shape with typically one axon and several dendrites reflects this asymmetry. Although neurons assume many different shapes and sizes they always maintain these two domains, which are essential for neuronal function. In the most simple view, neurons use their axon to transmit signals over long distances due to its capacity to extend to enormous lengths. Dendrites, on the other hand, are shorter and receive and integrate signals from different locations. The selection of the site where the axon and dendrites initially emerge during embryonic development is a tightly regulated event, eventually important for the correct formation of neuronal circuits, and disturbances of these processes can have pathological consequences due to circuit malformation. An important question is which mechanisms neurons utilize to specify the sites where axonal and dendrite outgrowth occurs and how their identities are maintained during and after development. The formation of these functionally diverse domains is the result of polarized differences of membrane and protein delivery, mitochondria transport, actin dynamics and microtubule stability. However how and in which temporal order all those events which coordinate the selection and maintenance of axons and dendrites is still under investigation. This selection of articles shall highlight new findings, which help to unravel all molecular and cellular events important for neuronal polarity establishment and maintenance.
Extracellular And Intracellular Signaling
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Author : James D. Adams
language : en
Publisher: Royal Society of Chemistry
Release Date : 2011
Extracellular And Intracellular Signaling written by James D. Adams and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
The Cytoskeleton
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Author : James Spudich
language : en
Publisher:
Release Date : 1996
The Cytoskeleton written by James Spudich and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Actin categories.
Cellular Migration And Formation Of Neuronal Connections
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-05-06
Cellular Migration And Formation Of Neuronal Connections written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-06 with Science categories.
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity
Cell Polarity 1
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Author : Klaus Ebnet
language : en
Publisher: Springer
Release Date : 2015-03-04
Cell Polarity 1 written by Klaus Ebnet and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-04 with Science categories.
This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 1 addresses cell polarity and cell migration (front-rear polarity), cell polarity and barrier formation (apico-basal polarity) and neuronal polarity. It particularly focuses on cell polarity at the molecular level and the underlying molecular mechanisms. It also elaborates the common principles and mechanisms that regulate cellular polarization in different cell types and contexts. Both volumes are intended for professors, group leaders and researchers in cell biology as well as medical professionals in the fields of anatomy, cell biology, physiology, pathology and tumor biology.
Model Systems To Study The Mechanisms Of Neural Development And Disease
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Author : Parthiv Haldipur
language : en
Publisher: Frontiers Media SA
Release Date :
Model Systems To Study The Mechanisms Of Neural Development And Disease written by Parthiv Haldipur and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.
Glycogen Synthase Kinase 3 Gsk 3 And Its Inhibitors
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Author : Ana Martinez
language : en
Publisher: John Wiley & Sons
Release Date : 2006-11-17
Glycogen Synthase Kinase 3 Gsk 3 And Its Inhibitors written by Ana Martinez and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-17 with Science categories.
Many researchers believe that GSK-3 and its inhibitors could lead to effective treatments for neurogenerative disorders, type II diabetes, depression and bipolar disorder, and some forms of cancer. This book provides a thorough introduction to GSK-3, presents up-to-date information, and mentions the birth of several chemical families of GSK-3 inhibitors with varying selectivity. It’s a great reference for researchers in drug design and development.
International Review Of Cytology
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Author : Kwang W. Jeon
language : en
Publisher: Elsevier
Release Date : 2006-07-31
International Review Of Cytology written by Kwang W. Jeon and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-31 with Science categories.
International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address roles of PACAP-containing retinal ganglion cells in circadian timing; cell polarity in filamenous fungi; cellular and molecular mechanics of gliding locomotion in eukaryotes; current strategies in overcoming resistance of cancer cell and apoptosis; cell and molecular biology of the exosome: how to make of break an RNA; human hair keratin associated proteins (KAPs).
Essays On Developmental Biology Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-03-09
Essays On Developmental Biology Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-09 with Science categories.
In 2016 Current Topics in Developmental Biology (CTDB) will celebrate its 50th or "golden anniversary. To commemorate the founding of CTDB by Aron Moscona (1921-2009) and Alberto Monroy (1913-1986) in 1966, a two-volume set of CTDB (volumes 116 and 117), entitled Essays on Development, will be published by Academic Press/Elsevier in early 2016. The volumes are edited by Paul M. Wassarman, series editor of CTDB, and include contributions from dozens of outstanding developmental biologists from around the world. Overall, the essays provide critical reviews and discussion of developmental processes for a variety of model organisms. Many essays relate the history of a particular area of research, others personal experiences in research, and some are quite philosophical. Essays on Development provides a window onto the rich landscape of contemporary research in developmental biology and should be useful to both students and investigators for years to come. - Covers the area of developmental processes for a variety of model organisms - International board of authors - Part of two 50th Anniversary volumes proving a comprehensive set of reviews edited by Serial Editor Paul M. Wassarman
Dendrites
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Author : Greg Stuart
language : en
Publisher: Oxford University Press
Release Date : 2016-04-07
Dendrites written by Greg Stuart and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-07 with Medical categories.
Dendrites are complex neuronal structures that receive and integrate synaptic input from other nerve cells. They therefore play a critical role in brain function. Although dendrites were discovered over a century ago, due to the development of powerful new techniques there has been a dramatic resurgence of interest in the properties and function of these beautiful structures. This is the third edition of the first book devoted exclusively to dendrites. It contains a comprehensive survey of the current state of dendritic research across a wide range of topics, from dendritic morphology, evolution, development, and plasticity through to the electrical, biochemical and computational properties of dendrites, and finally to the key role of dendrites in brain disease. The third edition has been thoroughly revised, with the addition of a number of new chapters and comprehensive updates or rewrites of existing chapters by leading experts. "Dendrites" will be of interest to researchers and students in neuroscience and related fields, as well as to anyone interested in how the brain works.