Neuropeptides In Neuroprotection And Neuroregeneration


Neuropeptides In Neuroprotection And Neuroregeneration
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Neuropeptides In Neuroprotection And Neuroregeneration


Neuropeptides In Neuroprotection And Neuroregeneration
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Author : Fred Nyberg
language : en
Publisher: CRC Press
Release Date : 2012-06-19

Neuropeptides In Neuroprotection And Neuroregeneration written by Fred Nyberg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-19 with Medical categories.


Although the genomic era is no longer in its infancy, the life sciences are still facing questions about the role of endogenous proteins and peptides in homeostasis and pathologies. Delving into one of the most current fields of interest in biology and medicine, Neuropeptides in Neuroprotection and Neuroregeneration describes the impact of neuropeptides on neuroprotection and neuroregeneration. The book begins with chapters describing important features of the endogenous neuropeptide systems related to their formation, receptor signaling, and inactivation. It includes chapters focused on the design and development of peptide-like drugs (peptidomimetics). In addition, the book covers: General aspects regarding the biosynthesis, structures, and distribution of neuroactive peptides and their receptors Basic mechanisms for neuropeptide action, metabolism, as well as techniques for their detection and aspects essential for the cellular mechanisms underlying brain pathology Neuropeptides known for their impact in neurodegenerative and neuroprotective processes Fundamental aspects as well as recent progress in the development of peptidomimetics of neuroprotective and cognition-enhancing peptides



Emerging Strategies In Neuroprotection


Emerging Strategies In Neuroprotection
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Author : Manangos
language : en
Publisher: Birkhäuser
Release Date : 1992-08-01

Emerging Strategies In Neuroprotection written by Manangos and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-08-01 with Science categories.


SOLOMON H. SNYDER Receptor Research Reaches Neurology: Relevance to Neurodegenerative Diseases and Stroke President George Bush has heralded the 1990s as the decade of the brain, based largely on the rapid escalation of advances in the molecular neuro sciences and the likelihood that these will bear therapeutic fruit before the turn of the century. There is little doubt that the 1970s and 1980s have witnessed more remarkable advances in the molecular neurosciences than all of the preceding hundred years. Identification of receptor sites for drugs and neurotransmitters along with simple, sensitive, and specific means of monitoring them has made it possible to elucidate the mechanism of action for many known drugs and to identify new chemical entities as potential therapeutic agents. At the same time, the numbers of distinct neurotrans mitters have multiplied. Prior to 1970 only the biogenic amines were well accepted as transmitters. The early 1970s witnessed the gradual acceptance of amino acids as major excitatory and inhibitory neurotransmitters. Identification of opiate receptors and the subsequent identification of the enkephalins as their endogenous ligands led to an appreciation of peptides as putative transmitters and the accumulation of as many as a hundred neuropeptides by the decade's end. In the 1980s the revolutions of molecular biology have been applied aggressively to the neurosciences with molecular cloning for neuropeptide precursors, many important neurochemical en zymes, and receptors for numerous transmitters.



Emerging Strategies In Neuroprotection


Emerging Strategies In Neuroprotection
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Author : Manangos
language : en
Publisher: Birkhäuser
Release Date : 2012-04-29

Emerging Strategies In Neuroprotection written by Manangos and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-29 with Science categories.


SOLOMON H. SNYDER Receptor Research Reaches Neurology: Relevance to Neurodegenerative Diseases and Stroke President George Bush has heralded the 1990s as the decade of the brain, based largely on the rapid escalation of advances in the molecular neuro sciences and the likelihood that these will bear therapeutic fruit before the turn of the century. There is little doubt that the 1970s and 1980s have witnessed more remarkable advances in the molecular neurosciences than all of the preceding hundred years. Identification of receptor sites for drugs and neurotransmitters along with simple, sensitive, and specific means of monitoring them has made it possible to elucidate the mechanism of action for many known drugs and to identify new chemical entities as potential therapeutic agents. At the same time, the numbers of distinct neurotrans mitters have multiplied. Prior to 1970 only the biogenic amines were well accepted as transmitters. The early 1970s witnessed the gradual acceptance of amino acids as major excitatory and inhibitory neurotransmitters. Identification of opiate receptors and the subsequent identification of the enkephalins as their endogenous ligands led to an appreciation of peptides as putative transmitters and the accumulation of as many as a hundred neuropeptides by the decade's end. In the 1980s the revolutions of molecular biology have been applied aggressively to the neurosciences with molecular cloning for neuropeptide precursors, many important neurochemical en zymes, and receptors for numerous transmitters.



Neuroprotection In Alzheimer S Disease


Neuroprotection In Alzheimer S Disease
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Author : Illana Gozes
language : en
Publisher: Academic Press
Release Date : 2016-12-30

Neuroprotection In Alzheimer S Disease written by Illana Gozes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-30 with Medical categories.


Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease



Modeling Of Microscale Transport In Biological Processes


Modeling Of Microscale Transport In Biological Processes
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Author : Sid Becker
language : en
Publisher: Academic Press
Release Date : 2016-12-27

Modeling Of Microscale Transport In Biological Processes written by Sid Becker and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-27 with Science categories.


Modeling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations. The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics. The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels. Features recent developments in theoretical and computational modeling for clinical researchers and engineers Furthers researcher understanding of fluid flow in biological media and focuses on biofluidics at the microscale Includes chapters expertly authored by internationally recognized authorities in the fundamental and applied fields that are associated with microscale transport in living media



Advances In Aging And Health Research


Advances In Aging And Health Research
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Author : Dr. Ian James Martins
language : en
Publisher: Scientific Research Publishing, Inc. USA
Release Date : 2018-09-13

Advances In Aging And Health Research written by Dr. Ian James Martins and has been published by Scientific Research Publishing, Inc. USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-13 with Juvenile Fiction categories.


In the current global epidemic for chronic diseases such as non alcoholic fatty liver disease (NAFLD), obesity, diabetes and neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease have become of major concern to the developed and developing world. Appetite regulation is involved in the aging process with the repression of anti-aging genes connected to insulin resistance and neurodegenerative diseases. Interests in the gene-environment interactions indicate that the anti-aging genes are connected to the metabolism of bacterial lipopolysaccharides (LPS), drugs and xenobiotics. In the developing world relevance to gram negative bacteria and increased plasma bacterial lipopolysaccharides (LPS) outer membrane endotoxins bindto cell membranes and interfere with cholesterol and amyloid beta (Aβ) interactionswith repression of anti-aging genes to mediate accelerated neuron death. Biotherapeutics and nutritional biotherapy have become important to reverse these global chronic diseases. Biotherapeutics that involve Indian spice therapy require reassessment with relevance to insulin therapy, immunotherapy, antimicrobial therapy and drug therapeutics. Combined insulin and Indian spice therapy interferes with human insulin biological activity relevant to the prevention of uncontrolled intracellular glucose levels and mitochondrial apoptosis. Magnesium therapy reverses cell senescence associated with various chronic diseases such as cardiovascular disease, diabetes and Alzheimer’s disease. Factors such as stress, core body temperature and food quality influence biotherapeutics with prevention of NAFLD, diabetes and neurodegenerative diseases.



Neurodegeneration And Neuroprotection In Parkinson S Disease


Neurodegeneration And Neuroprotection In Parkinson S Disease
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Author :
language : en
Publisher: Elsevier
Release Date : 1996-04-17

Neurodegeneration And Neuroprotection In Parkinson S Disease written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-04-17 with Medical categories.


Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most divers and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological, and therapeutic aspects of chosen research areas.



Neurodegeneration And Neuroprotection In Retinal Disease


Neurodegeneration And Neuroprotection In Retinal Disease
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Author : Giovanni Casini
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-21

Neurodegeneration And Neuroprotection In Retinal Disease written by Giovanni Casini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-21 with categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Computational Neuroscience


Computational Neuroscience
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Author : Diana Ivanova Stephanova
language : en
Publisher: CRC Press
Release Date : 2013-01-23

Computational Neuroscience written by Diana Ivanova Stephanova and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-23 with Medical categories.


This book covers the computer simulation of demyelinating neuropathies and neuronopathies and compares models with clinical findings. Through the approximation of nerve excitation and conduction, the authors show how the versatile structure of nerve fibers relates to different modes of focal prospects, inward and outward currents, conduction veloci



Neuroprotection


Neuroprotection
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Author : Matilde Otero-Losada
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-11-26

Neuroprotection written by Matilde Otero-Losada and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-26 with Medical categories.


Neurological disease affects nearly 25%–30% of the world’s population, exerting enormous financial strain on the healthcare system. Estimated current costs are around $800 annual billion, and this number is expected to increase exponentially as the global population ages. As such, new and alternative neuroprotective strategies are urgently needed. This book examines some of the most promising approaches in neuroprotection as well as discusses current goals and prospects. Organized into three sections, chapters cover such topics as the use of cannabinoids, medicinal plants, and essential oils in Alzheimer’s and Parkinson’s; protein misfolding and the neuroprotective potential of vitamin E in cerebral ischemia; and potential new neurological treatments and their mechanisms of action.