Neurosteroids And The Nervous System
DOWNLOAD
Download Neurosteroids And The Nervous System PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Neurosteroids And The Nervous System book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Neurosteroids And The Nervous System
DOWNLOAD
Author : Steven R. King
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-09
Neurosteroids And The Nervous System written by Steven R. King and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-09 with Medical categories.
While steroids from the periphery have profound effects on the nervous system, the nervous system also produces its own steroids de novo (“neurosteroids”). The physiological importance of neurosteroids is beginning to be understood. These steroids potentially have roles in sedative/hypnotic behavior, anxiety, learning, and memory. At the cellular level, neurosteroids affect neuronal excitability, synaptic plasticity and cell proliferation and survival. Early findings hold promise for future strategies to treat specific psychologicalconditions and neurological diseases. This Brief will focus on the current state of understanding of brainderived neurosteroids.
Neurosteroid Effects In The Central Nervous System
DOWNLOAD
Author : Sheryl S. Smith
language : en
Publisher: CRC Press
Release Date : 2003-10-27
Neurosteroid Effects In The Central Nervous System written by Sheryl S. Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-27 with Science categories.
Presenting a complete overview of the effects of steroid hormones in the brain and describing new methods for investigating these effects, this book discusses theories on steroid action in the central nervous system and the techniques for receptor localization and quantification and enzyme regulation. The author explores the use of transgenic/antisense strategies to determine sites and the cellular effects of steroid action in the brain. He covers steroid action on mood, cognition, sensorimotor action, neuroprotection, and plasticity, and describes methods using molecular, electrophysical, and behavioral techniques to link cellular mechanisms of steroid action with behavioral effects.
Neurosteroids And Brain Function
DOWNLOAD
Author : Giovanni Biggio
language : en
Publisher: Academic Press
Release Date : 2001-09-27
Neurosteroids And Brain Function written by Giovanni Biggio and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-09-27 with Medical categories.
International Review of Neurobiology, Volume 46 presents in-depth reviews on such ground-breaking topics as assembly and intracellular trafficking of GABA A receptors, D-1 dopamine receptors, and Alzheimer's disease. This series offers the most comprehensive and up-to-date information available and is a must for anyone in the field. Includes a historical overview of neurosteroid research Contains a chapter on neurosteroid biosynthesis and regulation Presents current methods of neurosteroid measurement and analysis Discusses neurosteroid function in both the normal and the pathological brain Chapters address the function of neurosteroid in: Stress, Receptor plasticity and function, Learning and Memory, Alcohol use, Depression
Neurosteroids
DOWNLOAD
Author : Hubert Vaudry
language : en
Publisher: Frontiers E-books
Release Date :
Neurosteroids written by Hubert Vaudry and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Thirty years ago, the group of Baulieu and colleagues discovered that certain steroid hormones were present in higher amounts in the brain than in the plasma, and also found that suppression of circulating steroids by adrenalectomy and castration did not affect the concentration of pregnenolone, dehydroepiandrosterone and their sulfate esters in the rat brain. These seminal observations led to the concept that the brain, in very much the same way as the adrenal cortex, testis, ovary and placenta, was capable of synthesizing steroids. These brain born steroids, called neurosteroids, have been found to exert a vast array of biological activities. A number of steroidogenic enzymes have now been identified in the central nervous system by immunohistochemistry and in situ hybridization, and the neuronal and hormonal mechanisms regulating the biosynthesis of neurosteroids have been partially elucidated. The aim of this Research Topic is to celebrate three decades of research on neurosteroids by gathering a bouquet of review papers and original articles from leading scientists in the flourishing field of neurosteroids.
Neuroactive Steroids In Brain Function Behavior And Neuropsychiatric Disorders
DOWNLOAD
Author : Abraham Weizman
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01
Neuroactive Steroids In Brain Function Behavior And Neuropsychiatric Disorders written by Abraham Weizman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Medical categories.
This book provides an up-to-date overview of the role of neurosteroids and neuroactive steroids in the regulation of brain processes and neuropsychiatric disorders. It addresses the neurosteroid function in brain development and plasticity, in both the normal and the pathological brain. It also suggests possible therapeutic approaches to the use of natural occurring or sinthetic neurosteroids. The contributors suggest that neuroactive steroids could have a role in clinical practice.
Recent Progress And Perspectives In Neurosteroid Research
DOWNLOAD
Author : Hubert Vaudry
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-16
Recent Progress And Perspectives In Neurosteroid Research written by Hubert Vaudry and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-16 with Science categories.
Neuroplasticity Development And Steroid Hormone Action
DOWNLOAD
Author : Robert J. Handa
language : en
Publisher: CRC Press
Release Date : 2001-07-30
Neuroplasticity Development And Steroid Hormone Action written by Robert J. Handa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-30 with Medical categories.
A compilation of cutting-edge research, Neuroplasticity, Development, and Steroid Hormone Action explores the effects of steroid hormones on brain development, function, and aging. The experimental approaches used by the authors ranges from molecular to behavioral and endocrine to neurobiological. It contains scientific photographs, line drawings, tables, color illustrations, and graphs, this interesting and timely text covers the neuroplastic effects of steroid hormones throughout the lifetime of various animal models, such as bees, fish, lizards, turtles, birds, mice, rats, and primates.
The Rat Nervous System
DOWNLOAD
Author : George Paxinos
language : en
Publisher: Academic Press
Release Date : 2014-07-01
The Rat Nervous System written by George Paxinos and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Science categories.
The previous editions of The Rat Nervous System were indispensable guides for those working on the rat and mouse as experimental models. The fourth edition enhances this tradition, providing the latest information in the very active field of research on the brain, spinal cord, and peripheral nervous system. The structure, connections, and function are explained in exquisite detail, making this an essential book for any graduate student or scientist working on the rat or mouse nervous system. - Completely revised and updated content throughout, with entirely new chapters added - Beautifully illustrated so that even difficult concepts are rendered comprehensible - Provides a fundamental analysis of the anatomy of all areas of the central and peripheral nervous systems, as well as an introduction to their functions - Appeals to researchers working on other species, including humans
New Perspectives In Neurosteroids Action A Special Player Allopregnanolone
DOWNLOAD
Author : Valerio Magnaghi
language : en
Publisher: Frontiers Media SA
Release Date : 2015-07-01
New Perspectives In Neurosteroids Action A Special Player Allopregnanolone written by Valerio Magnaghi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-01 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Early in the 80’s date the first observations on the existence of hormonal steroids that may be synthesized and act in the nervous system. In order to refer to these endogenous steroids, proved important to control both central and peripheral nervous system, it was proposed the term “neurosteroids” (NSs). Over the years, their importance in regulating the physiological functions of neuronal and glial cells increased progressively. These steroids can be involved in several pathophysiological conditions such as depression, anxiety, premenstrual syndrome (PMS), schizophrenia and Alzheimer disease. Among the different classes of NSs, the progestagens revealed particularly important. The progesterone metabolite 5a-pregnan-3a-ol-20-one, also named tetrahydroprogesterone or allopregnanolone (ALLO) was one of the first most important steroid that was originally shown to act as neurosteroid. ALLO is synthesized through the action of the 5aR-3a-HSD, which converts P into DHP and subsequently, via a bidirectional reaction, into ALLO. NSs exert complex effects in the nervous system through ‘classic’, genomic, and ‘non-classic’, non-genomic actions. ALLO displays a rapid ‘non-genomic’ effect, which mainly involves the potent modulation of the GABA type A (GABA-A) receptor function. Recently a membrane receptor has been identified as target for ALLO effects, i.e. the membrane progesterone receptors (mPRs) that are able to activate a signalling cascade through G protein dependent mechanisms. By these ways, ALLO is able to modulate several cell functions, acting as neurogenic molecule on neural progenitor cells, as well as by activating proliferation and differentiation of glial cells in the central and peripheral nervous system. In this topic, we review the most recent acquisitions in the field of neurosteroids, focusing our attention on ALLO because its effects on the physiology of neurons and glial cells of the central and peripheral nervous system are intriguing and could potentially lead to the development of new strategies for neuroprotection and/or regeneration of injured nervous tissues and for the treatment of neuropsychiatric disorders.
Non Reproductive Actions Of Sex Steroids
DOWNLOAD
Author : Gregory R. Bock
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Non Reproductive Actions Of Sex Steroids written by Gregory R. Bock and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
Prominent clinicians and researchers from diverse disciplines discuss the basic cell and molecular biology of steroid action and sex steroids' effects on the nervous and immune systems. Provides an integrated evaluation of the advantages and disadvantages of hormone replacement therapy.