New Bioprocessing Strategies Development And Manufacturing Of Recombinant Antibodies And Proteins
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New Bioprocessing Strategies Development And Manufacturing Of Recombinant Antibodies And Proteins
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Author : Bob Kiss
language : en
Publisher: Springer
Release Date : 2018-12-06
New Bioprocessing Strategies Development And Manufacturing Of Recombinant Antibodies And Proteins written by Bob Kiss and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-06 with Science categories.
This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Introduction To Antibody Engineering
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Author : Florian Rüker
language : en
Publisher: Springer Nature
Release Date : 2020-11-30
Introduction To Antibody Engineering written by Florian Rüker and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-30 with Medical categories.
This highly readable textbook serves as a concise and engaging primer to the emerging field of antibody engineering and its various applications. It introduces readers to the basic science and molecular structure of antibodies, and explores how to characterize and engineer them. Readers will find an overview of the latest methods in antibody identification, improvement and biochemical engineering. Furthermore, alternative antibody formats and bispecific antibodies are discussed. The book’s content is based on lectures for the specializations “Protein Engineering” and “Medical Biotechnology” within the Master’s curriculum in “Biotechnology.” The lectures have been held at the University of Natural Resources and Life Sciences, Vienna, in cooperation with the Medical University of Vienna, since 2012 and are continuously adapted to reflect the latest developments in the field. The book addresses Master- and PhD students in biotechnology, molecular biology and immunology, and all those who are interested in antibody engineering.
Bioprocessing Bioengineering And Process Chemistry In The Biopharmaceutical Industry
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Author : Kumar Gadamasetti
language : en
Publisher: Springer Nature
Release Date : 2024-11-23
Bioprocessing Bioengineering And Process Chemistry In The Biopharmaceutical Industry written by Kumar Gadamasetti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-23 with Technology & Engineering categories.
This book outlines how advances in the diverse scientific and engineering disciplines of synthetic biology, DNA synthesis, production of protein therapeutics, and bioinformatics have led to the commercialization of new complex biotherapeutic modalities in modern era, including monoclonal and multi-specific antibodies, antibody drug conjugates (ADC), fusion proteins, CAR-T and CRISPR technologies and applications, mRNA vaccines and more. Enabling operations to bring these life-changing medicines into the hands of the needy patients include regulatory submissions to authorities across the globe, as well as streamlined production across manufacturing networks deemed necessary and are outlined in dedicated chapters. Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical Industry: Using Chemistry and Bioengineering to Improve the Performance of Biologics captures the state of the art for many of these new modalities, offering innovative approaches to treat, prevent, and in some providential cases, cure the disease. This book will be of significant interest for many disciplines engaged jointly as teams convergently in delivering these medicines: bioprocess engineers, biologists, chemists, bioengineers, genetic engineers, healthcare professionals, regulatory bodies, among pharmaceutical industry professionals as well as in academic circles.
The Future Of Pharmaceuticals
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Author : Sarfaraz K. Niazi
language : en
Publisher: CRC Press
Release Date : 2022-02-28
The Future Of Pharmaceuticals written by Sarfaraz K. Niazi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-28 with Medical categories.
Before now, biological systems could only be expressed in terms of linear relationships, however, as knowledge grows and new techniques of analysis on biological systems is made available, we are realizing the non-linearity of these systems. The concepts and techniques of nonlinear analysis allow for more realistic and accurate models in science. The Future of Pharmaceuticals: A Nonlinear Analysis provides an opportunity to understand the non-linearity of biological systems and its application in various areas of science, primarily pharmaceutical sciences. This book will benefit professionals in pharmaceutical industries, academia, and policy who are interested in an entirely new approach to how we will treat disease in the future. Key Features: Addresses a new approach of nonlinear analysis. Applies a theory of projection to chalk out the future, instead of basing on linear evolution. Provides an opportunity to better understand the non-linearity in biological systems and its applications in various areas of science, primarily pharmaceutical sciences. Helps change the thought process for those looking for answers to their questions which they do not find in the linear relationship approach. Encourages a broader perspective for the creative process of drug development.
Heterologous Protein Production In Cho Cells
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Author : Paula Meleady
language : en
Publisher: Springer Nature
Release Date : 2024-10-26
Heterologous Protein Production In Cho Cells written by Paula Meleady and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-26 with Science categories.
This detailed new edition explores the use of Chinese hamster ovary (CHO) cells in the production of therapeutic protein products. Beyond updates on earlier methodologies, the book also delves into the genetic manipulation of CHO cells for recombinant protein production, analysis of CHO cells using proteomic and metabolomic approaches, as well as methods for the characterization of recombinant protein products, such as glycosylation and host cell protein analysis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Heterologous Protein Production in CHO Cells: Methods and Protocols, Second Edition is an ideal guide for researchers working to enhance and accelerate CHO productive capabilities in the coming decades.
Digital Twins
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Author : Christoph Herwig
language : en
Publisher: Springer Nature
Release Date : 2021-04-25
Digital Twins written by Christoph Herwig and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-25 with Technology & Engineering categories.
This is the first of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book explains the mathematical structure of digital twins, their development and the model’s respective parts, as well as concepts for the knowledge-driven generation and structural variability of digital twins. Covering fundamentals as well as applications, the two volumes offer the ideal introduction to the topic for researchers in academy and industry alike.
Ion Exchange Chromatography And Related Techniques
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Author : Pavel Nesterenko
language : en
Publisher: Elsevier
Release Date : 2023-11-15
Ion Exchange Chromatography And Related Techniques written by Pavel Nesterenko and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-15 with Technology & Engineering categories.
Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference source of current information for analytical and biopharmaceutical chemists. - Includes individual chapters written by recognized authoritative and visionary experts in the field to provide an overview and focused treatment of a single topic - Presents comprehensive coverage of ion-exchange techniques from theory, to methods, to selected applications for ions and biopolymers - Provides Tables and diagrams with commonly used data to facilitate practical work, comparison of results and decision-making
Proceedings Of 2020 Chinese Intelligent Systems Conference
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Author : Yingmin Jia
language : en
Publisher: Springer Nature
Release Date : 2020-09-23
Proceedings Of 2020 Chinese Intelligent Systems Conference written by Yingmin Jia and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-23 with Technology & Engineering categories.
The book focuses on new theoretical results and techniques in the field of intelligent systems and control. It provides in-depth studies on a number of major topics such as Multi-Agent Systems, Complex Networks, Intelligent Robots, Complex System Theory and Swarm Behavior, Event-Triggered Control and Data-Driven Control, Robust and Adaptive Control, Big Data and Brain Science, Process Control, Intelligent Sensor and Detection Technology, Deep learning and Learning Control Guidance, Navigation and Control of Flight Vehicles and so on. Given its scope, the book will benefit all researchers, engineers, and graduate students who want to learn about cutting-edge advances in intelligent systems, intelligent control, and artificial intelligence.
Recent Advances In Industrial Biochemistry
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Author : Muhammad Zaffar Hashmi
language : en
Publisher: Springer Nature
Release Date : 2024-05-08
Recent Advances In Industrial Biochemistry written by Muhammad Zaffar Hashmi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-08 with Science categories.
Biochemistry is concerned with the chemical processes that occur within living organisms and microorganisms. There have been a number of publications focusing on biochemistry and its use for understanding biochemical and molecular mechanisms, with the majority of the literature focusing on bench scale items. To date there has not been a comprehensive work focusing on the techno-economic and industrial aspects of biochemistry from the microeconomic and pilot scales. This text covers current innovations and advances in plant biochemistry, animal biochemistry, microbial biochemistry and medicinal biochemistry plus potential uses of proteomics, genomics, recombinant DNA technology and protein application. Recent Advances in Industrial Biochemistry focuses on methods for recombinant proteins production and purification plus metabolic engineering and other source technologies from the industrial viewpoint, providing comprehensive, up-to-date information and evidence on contemporary development in the field of industrial biochemistry. The major focus of this book is the key issues, opportunities, approaches, advancements, products, innovations and technologies in current biochemistry from micro scale to production at pilot scale. Chapters highlight the many potential commercial prospects in various industries from food to to pharmaceuticals to bioenergy, providing a valuable and unique single resource for researchers.
Principles Of Multiple Liquid Separation Systems
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Author : Kit Wayne Chew
language : en
Publisher: Elsevier
Release Date : 2023-01-12
Principles Of Multiple Liquid Separation Systems written by Kit Wayne Chew and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-12 with Technology & Engineering categories.
Principles of Multiple-Liquid Separation Systems: Interaction, Application and Advancement describes the basic principles and advancements of multiple-liquid separation systems in downstream processing. Several important elements are included, such as the fundamental process and mechanisms of the multiple-liquid separation system, key principles of the interaction between different solvents and phase components, applications, and green solvents for the separation system. Furthermore, the book gives insights in commercializing this separation technique to industrial scale and making the process environmentally and economically sustainable. The book also presents constructive critics of this separation technique for both past and the latest findings. - Comprehensively reviews several advanced separation methods and their fundamentals in a single source - Covers a deep understanding of the interaction between various liquid phase techniques and the latest cases of advanced techniques applied in bioprocesses - Provides a critical and constructive judgement of costs and environmental sustainability of multiple-liquid separation systems