New Directions In The Management Of Status Epilepticus
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New Directions In The Management Of Status Epilepticus
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Author : Batool F. Kirmani
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-06
New Directions In The Management Of Status Epilepticus written by Batool F. Kirmani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with categories.
Status Epilepticus (SE) is a neurological emergency and has high morbidity and mortality. The International League Against Epilepsy (ILAE) recently updated their definition to specify that, “SE is a condition resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms, which lead to abnormally, prolonged seizures.” Such phenomena can lead to long-term neurological complications due to neuronal death, glia, neurological injury, aberrant neuroplasticity, oxidative stress and inflammation, and alteration of neuronal networks. Depending upon the type and duration of SE, these mechanisms are quite variable. Therefore, in response to the updated definition of SE, novel avenues of research are required to address the specified involvement of the underlying mechanisms and pathophysiology resulting in the development of and outcomes from SE. Improving the basic science understanding of SE will facilitate essential clinical trials. One can envision such experiments to include device and compound-based technological interventions directed at aborting the seizure activity and improving clinical outcomes. Benzodiazepines remain one of the cornerstones of treatment, and studies are underway to study new delivery options, including intranasal, buccal, and intramuscular midazolam, in addition to rectal diazepam, with the goal of aborting the seizure activity outside the hospitals, as rapidly as possible. Approved and off-label anticonvulsants, such as phenytoin, phenobarbital, valproate, topiramate, levetiracetam, lacosamide, steroids, immunosuppressants, and neuroprotective compounds, have also shown some efficacy at treating SE. However, substantial challenges remain in optimally managing SE and minimizing the short- and long-term complications. Such difficulties can be overcome by innovative approaches targeting the underlying mechanisms of neuronal excitability, glia, neuronal death, neuroplasticity, oxidative stress, inflammation, and neuroinflammation.
Status Epilepticus
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Author : Ashalatha Radhakrishnan
language : en
Publisher: JP Medical Ltd
Release Date : 2017-09-30
Status Epilepticus written by Ashalatha Radhakrishnan and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-30 with Medical categories.
Status Epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them. SE is a life-threatening medical emergency particularly if treatment is delayed. This book is a concise guide to Status Epilepticus for practitioners and trainees. Beginning with an overview of the condition and the evolution of its definition over the years, the following chapters discuss prehospital management and investigations and monitoring. The remaining sections cover management therapies. A flow chart and protocols are included to assist management in intensive care units and questions and answers are provided at the end of each chapter to enhance learning. Key points Concise guide to diagnosis and management of Status Epilepticus Covers different management therapies Includes flow chart and protocols to assist management in intensive care units Questions and answers at the end of each chapter enhance learning
Oh S Intensive Care Manual
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Author : Andrew D. Bersten
language : en
Publisher: Elsevier Health Sciences
Release Date : 2009-01-01
Oh S Intensive Care Manual written by Andrew D. Bersten and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-01 with Medical categories.
The sixth edition provides practical, concise information on all aspects of intensive care. Written in a clear and accessible style and now for the first time presented in colour throughout, this book enables the user to manage a patient in an ICU setting effectively without recourse to large text/reference works or specialized monographs. This thoroughly revised and updated edition reflects the best and most current practice from leading centres in Australia, the UK and Western Europe. Information on management and treatment of conditions is balanced by pathophysiological and pharmacological background. This is not just a "cook book" of procedures. It provides all of the essential information for candidates wishing to pass professional examinations. Addition of colour throughout to highlight summary boxes, tables, charts and flow diagrams.Will make key information more accessible, easier and faster to retrieve. Pitfalls in treatment and management emphasized in each chapter.Providers the user with expert advice on practical issues that will be encountered on a day-to-day basis in the ICU. Keeps the user abreast of the latest developments in diagnosis and management.
Oh S Intensive Care Manual E Book
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Author : Andrew D Bersten
language : en
Publisher: Elsevier Health Sciences
Release Date : 2008-12-05
Oh S Intensive Care Manual E Book written by Andrew D Bersten and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-05 with Medical categories.
The sixth edition of Oh’s Intensive Care Manual provides practical, concise information on all aspects of intensive care. Written in a clear and accessible style and now for the first time presented in colour throughout, this book enables the user to manage a patient in an ICU setting effectively without recourse to large text/reference works or specialized monographs. This thoroughly revised and updated edition reflects the best and most current practice from leading centres in Australia, the UK and Western Europe. Although primarily intended for the trainee and practitioner in intensive care, nurses and other allied health professionals will find that this is an invaluable tool in helping to deal with a broad spectrum of conditions encountered in the ICU. Represents a consensus of practice/standard of care in Australia/NZ, UK and Europe. Treatment guidelines are authoritative since they follow those that are Recommended/laid down by Professional societies. Comprehensive, covers all important areas of intensive care medicine. Provides a single resource that will cover everything that a user will need to know during the course of an ICU rotation. No need to refer to a larger textbook. Information on management and treatment of conditions is balanced by pathophysiological and pharmacological background. This is not just a "cook book" of procedures. It provides all of the essential information for candidates wishing to pass professional examinations. Covers the paediatric as well as the adult patient in the ICU. Provides quick access and practical guidance for all clinical scenarios. Extensive list of key references most taken from the last three years. Helps trainees and practitioners prepare for case conference/presentations. Addition of colour throughout to highlight summary boxes, tables, charts and flow diagrams.Will make key information more accessible, easier and faster to retrieve. Line drawings extensively re-done in colour throughout.Will improve the user’s understanding of the physiological processes under discussion. 5-10 Key points added at end of chapters. Will provide the user with a useful summary of the essential bottom line information. Pitfalls in treatment and management emphasized in each chapter.Providers the user with expert advice on practical issues that will be encountered on a day-to-day basis in the ICU. Includes the most current classification and “clinical scoring schemes. Keeps the user abreast of the latest developments in diagnosis and management.
Netter S Neurology E Book
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Author : Jayashri Srinivasan
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-02-25
Netter S Neurology E Book written by Jayashri Srinivasan and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-25 with Medical categories.
Perfect for residents, medical students, generalists, nurses, and other healthcare professionals who need a practical, working knowledge of neurology, Netter's Neurology, 3rd Edition, provides a concise overview highlighted by unique, memorable Netter illustrations. This award-winning visual resource showcases the well-known work of Frank H. Netter, MD, and his successor, Carlos Machado, MD, a physician who has created clear, full-color illustrations in the Netter tradition. Offers a quick and memorable summary of general neurology and its intersection with internal medicine, neurosurgery, ophthalmology, psychiatry, and orthopaedics. Concise text is presented in a templated format for fast, easy access to information. Features more than 450 Netter and Netter-style images that highlight anatomy, pathophysiology, and clinical presentation related to neuroanatomical and neurologic concepts. Helps you make correlations between anatomy, pathology, physiology, and pharmacology in a clinical setting. Clinical vignettes throughout provide real-world applications to each topic. Features new chapters on Laboratory Evaluation in Neurology; Neuroimaging in Neurologic Disorders; and Neurologic Emergencies and Critical Care. Presents the underlying anatomy in living patients through neuroimaging coverage, including MR, CT, and PET.
Refractory Status Epilepticus
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Author : Xuefeng Wang
language : en
Publisher: Springer
Release Date : 2017-09-05
Refractory Status Epilepticus written by Xuefeng Wang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-05 with Medical categories.
This book aims to offer the accumulated fertile experience of treating drug-resistant epileptic patients collected over the past few decades, focusing on aspects of neurology, neurosurgery, emergency care, critical care medicine and basic medical research. Refractory status epilepticus is one of the most common severe and acute diseases in neurology and neurocritical care; it is also the main cause of death in epileptic patients. In the context of prevention and treatment processes, it is not only necessary to terminate epileptic seizures, but to also address the disruption of the patient’s internal environment and provide critical life support. Effective treatment calls for multi-disciplinary support from neurology, neurosurgery, emergency care, critical care medicine, and other fields. Further, since the clinical features of epileptic seizure are not specific, it is necessary to differentiate it from other diseases that produce convulsions, disorders of consciousness, syncope, mental and behavioral disorders, myoclonus, etc., to avoid misdiagnosis. In this book, it comprehensively and systematically describes the basic knowledge as well as prevention and treatment tips, providing an invaluable reference resource for medical students and professionals in neurology, neurosurgery, emergency care and critical care medicine.
Insights In Brain Disease Mechanisms 2021
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Author : Detlev Boison
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-21
Insights In Brain Disease Mechanisms 2021 written by Detlev Boison and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-21 with Science categories.
Pellock S Pediatric Epilepsy
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Author : Douglas R. Nordli, Jr., MD
language : en
Publisher: Springer Publishing Company
Release Date : 2016-08-28
Pellock S Pediatric Epilepsy written by Douglas R. Nordli, Jr., MD and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-28 with Medical categories.
Now in its fourth edition, Pellock’s Pediatric Epilepsy: Diagnosis and Therapy remains the gold standard for diagnosis, treatment, classification, and management of childhood epilepsies. With over 100 distinguished contributors from world-leading epilepsy programs, the long-awaited new edition maintains the breadth and scope the book is known for while significantly updating the science, practice, and therapeutic strategies that continue to move the field forward. At the center of this new edition is the totally reorganized and expanded section on age-related syndromes. There is a major emphasis on new genetic-based classifications and the clinical implications for identifying and managing the various subtypes. New chapters devoted exclusively to Panayiotopoulos syndrome, myoclonic status epilepticus, and autosomal dominant focal epilepsies, among others, cover even more ground than the last edition. Brand-new chapters in the drug and diet section cover perampanel, ezogabine, and lacosamide, while the existing chapters on major medical treatments have been comprehensively updated to reflect the latest trials and studies. Other sections contain new chapters on genetics, non-invasive functional mapping, sleep issues for pediatric epilepsy patients, and more. With more than 80 chapters, Pellock’s Pediatric Epilepsy now contains a full discussion of the spectrum of epilepsy disorders, not just seizures. From basic mechanisms and epidemiology, through diagnosis and therapy, to quality of life issues, the new edition of this established reference covers every aspect of childhood epilepsy and will continue to be the definitive core text for all professionals involved in the field. New to the Fourth Edition: Every chapter thoroughly reviewed, revised, and updated Section on age-related syndromes completely reconfigured to align with new ILAE terminology and organization in classifying seizures and forms of epilepsy Major update on disease mechanisms and all treatments for epilepsy, including drugs Increased attention to special populations, including a heavily-updated chapter on the female epilepsy patient New final section covers the epilepsy spectrum, with new chapters on epilepsy and sleep, co-morbidities of childhood, behavioral influence of AEDs, and transitioning to adulthood
Textbook Of Adult Emergency Medicine E Book
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Author : Peter Cameron
language : en
Publisher: Elsevier Health Sciences
Release Date : 2011-11-18
Textbook Of Adult Emergency Medicine E Book written by Peter Cameron and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-18 with Medical categories.
A major postgraduate textbook in emergency medicine, covering all the major topics that present to the trainee doctor in the emergency department. A comprehensive textbook of adult emergency medicine for trainee doctors - covers all the problems likely to present to a trainee in the emergency department. Chapters are short and concise, with key point boxes (called "Essentials") at the beginning. Also has boxes featuring controversial areas of treatment. Practical and clinically orientated. Major changes to resuscitation guidelines. Complete rewriting of ENT section. Significant updating of following topics - acute coronary syndrome management, trauma, sepsis management, imaging, arrhythmias. Expansion of administration section - especially patient safety. Changes to drug overdose sections in toxicology section.
Pharmacology For Canadian Health Care Practice
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Author : Kara Sealock
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-08-05
Pharmacology For Canadian Health Care Practice written by Kara Sealock and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-05 with Medical categories.
Let this outstanding, reader-friendly pharmacology text help guide you through the detailed world of nursing pharmacology. Now in its third edition, Pharmacology for Canadian Health Care Practice covers all the key pharmacology content needed by today's nursing students. Known for its appealing layout, wealth of photos, and helpful boxed features, this engaging text brings important pharmacology concepts to life. The text's popular key drug approach focuses only on the drug information you need to know. Along with its exam preparation and insightful learning strategies, this is your complete pharmacology text!