Status Epilepticus


Status Epilepticus
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Status Epilepticus


Status Epilepticus
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Author : Ashalatha Radhakrishnan
language : en
Publisher: JP Medical Ltd
Release Date : 2017-09-30

Status Epilepticus written by Ashalatha Radhakrishnan and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-30 with Medical categories.


Status Epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them. SE is a life-threatening medical emergency particularly if treatment is delayed. This book is a concise guide to Status Epilepticus for practitioners and trainees. Beginning with an overview of the condition and the evolution of its definition over the years, the following chapters discuss prehospital management and investigations and monitoring. The remaining sections cover management therapies. A flow chart and protocols are included to assist management in intensive care units and questions and answers are provided at the end of each chapter to enhance learning. Key points Concise guide to diagnosis and management of Status Epilepticus Covers different management therapies Includes flow chart and protocols to assist management in intensive care units Questions and answers at the end of each chapter enhance learning



Status Epilepticus


Status Epilepticus
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Author : Frank W. Drislane
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-28

Status Epilepticus written by Frank W. Drislane and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-28 with Medical categories.


A panel of senior clinicians critically reviews the many forms of status epilepticus (SE), their causes, manifestations, methods of diagnosis, and appropriate treatments. The emphasis is on the disease as encountered by the clinician in the field and the importance of correct recognition and diagnosis. The authors provide for each form of SE the underlying genetic, biological, and developmental background, the pathophysiological processes, as well as the precipitating factors that lead to an episode. For the difficult problem of diagnosing nonconvulsive SE, they offer detailed syndrome classifications, differential diagnoses, descriptions of seizure "imitators," notes on unusual behavioral and cognitive manifestations, and carefully delineated clinical presentations. Additional highlights include striking EEG reproductions that provide classic examples of patients in SE, SE in very young children and neonates, and an analysis of the cellular physiology and processes occurring during SE.



Refractory Status Epilepticus


Refractory Status Epilepticus
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Author : Xuefeng Wang
language : en
Publisher: Springer
Release Date : 2017-09-05

Refractory Status Epilepticus written by Xuefeng Wang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-05 with Medical categories.


This book aims to offer the accumulated fertile experience of treating drug-resistant epileptic patients collected over the past few decades, focusing on aspects of neurology, neurosurgery, emergency care, critical care medicine and basic medical research. Refractory status epilepticus is one of the most common severe and acute diseases in neurology and neurocritical care; it is also the main cause of death in epileptic patients. In the context of prevention and treatment processes, it is not only necessary to terminate epileptic seizures, but to also address the disruption of the patient’s internal environment and provide critical life support. Effective treatment calls for multi-disciplinary support from neurology, neurosurgery, emergency care, critical care medicine, and other fields. Further, since the clinical features of epileptic seizure are not specific, it is necessary to differentiate it from other diseases that produce convulsions, disorders of consciousness, syncope, mental and behavioral disorders, myoclonus, etc., to avoid misdiagnosis. In this book, it comprehensively and systematically describes the basic knowledge as well as prevention and treatment tips, providing an invaluable reference resource for medical students and professionals in neurology, neurosurgery, emergency care and critical care medicine.



Status Epilepticus


Status Epilepticus
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Author : Claude G. Wasterlain
language : en
Publisher: MIT Press
Release Date : 2006

Status Epilepticus written by Claude G. Wasterlain and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.


A comprehensive review of recent advances in the most severe form of epilepsy, focusing on two areas in which progress has been most rapid: basic mechanisms and treatment. Interest in status epilepticus--the most extreme form of epilepsy, involving continuous seizures--has surged in the last 20 years. Since 1979 there have been over 4,000 publications on the subject, including more than 1,700 in the last five years. No other text provides such a comprehensive review of the recent advances in the field of status epilepticus. The book focuses on the two areas in which progress has been most rapid: basic mechanisms and treatment. There is now a greater understanding of the mechanisms and complications of status epilepticus at the molecular level, which should eventually lead to improved therapy, and treatment strategies today have a greater sense of urgency because of the realization that neuronal apoptosis and necrosis can be triggered very quickly. After an overview of history, classification, and epidemiology, the contributors consider clinical phenomenology, biological markers, pathophysiology, brain damage, epileptogenesis, therapeutic principles, pharmacology, and therapeutic management. Their contributions are equally divided between studies of basic mechanisms in animal models and clinical studies, so that the reader can turn easily from the reductionist experiment that isolates a small component of status to the complex clinical situation in which these principles can translate into therapeutic action. The goal is to provide a scientific rationale for clinical decisions while developing therapeutic attitudes that are firmly grounded in pathophysiology.



New Directions In The Management Of Status Epilepticus


New Directions In The Management Of Status Epilepticus
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Author : Batool F. Kirmani
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-06

New Directions In The Management Of Status Epilepticus written by Batool F. Kirmani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-06 with categories.


Status Epilepticus (SE) is a neurological emergency and has high morbidity and mortality. The International League Against Epilepsy (ILAE) recently updated their definition to specify that, “SE is a condition resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms, which lead to abnormally, prolonged seizures.” Such phenomena can lead to long-term neurological complications due to neuronal death, glia, neurological injury, aberrant neuroplasticity, oxidative stress and inflammation, and alteration of neuronal networks. Depending upon the type and duration of SE, these mechanisms are quite variable. Therefore, in response to the updated definition of SE, novel avenues of research are required to address the specified involvement of the underlying mechanisms and pathophysiology resulting in the development of and outcomes from SE. Improving the basic science understanding of SE will facilitate essential clinical trials. One can envision such experiments to include device and compound-based technological interventions directed at aborting the seizure activity and improving clinical outcomes. Benzodiazepines remain one of the cornerstones of treatment, and studies are underway to study new delivery options, including intranasal, buccal, and intramuscular midazolam, in addition to rectal diazepam, with the goal of aborting the seizure activity outside the hospitals, as rapidly as possible. Approved and off-label anticonvulsants, such as phenytoin, phenobarbital, valproate, topiramate, levetiracetam, lacosamide, steroids, immunosuppressants, and neuroprotective compounds, have also shown some efficacy at treating SE. However, substantial challenges remain in optimally managing SE and minimizing the short- and long-term complications. Such difficulties can be overcome by innovative approaches targeting the underlying mechanisms of neuronal excitability, glia, neuronal death, neuroplasticity, oxidative stress, inflammation, and neuroinflammation.



Status Epilepticus


Status Epilepticus
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Author : Simon Shorvon
language : en
Publisher: Cambridge University Press
Release Date : 1994-07-21

Status Epilepticus written by Simon Shorvon and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-07-21 with Medical categories.


An invaluable reference work comprehensively reviewing current knowledge and treatment of Status Epilepticus.



Nonconvulsive Status Epilepticus


Nonconvulsive Status Epilepticus
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Author : Frank W. Drislane, MD
language : en
Publisher: Demos Medical Publishing
Release Date : 2008-11-05

Nonconvulsive Status Epilepticus written by Frank W. Drislane, MD and has been published by Demos Medical Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-05 with Medical categories.


The only comprehensive source of information on this frequently misdiagnosed problem, with information critical for physicians, ER and ICU doctors, and psychiatrists. An under-recognized condition that can potentially cause brain damage and even death, nonconvulsive status epilepticus (NCSE) is an important clinical problem, occurring in about 25% of status epilepsy cases. Despite this prevalence, Nonconvulsive Status Epilepticus is the first comprehensive clinical text to cover its diagnosis and management. The book progresses logically, beginning with chapters discussing the history and classification of NCSE, reflecting a contemporary understanding of developmental, syndromic, and clinical aspects. Following chapters discuss relevant epidemiology, electrophysiology, imaging and pathophysiology of NCSE, with supplementary sections devoted to psychiatric and behavioral aspects of NCSE and to the different diagnostic considerations of its frequently unusual behavioral presentations. Highlights include: An emphasis on diagnosis, management, and all pertinent clinical issues A heavily illustrated section on EEG interpretation in NCSE Contributions by the foremost international experts on NCSE Throughout, the book maintains a practical focus on recognizing the key signs and symptoms of this subtly presented and clinically challenging condition. This multidisciplinary volume will provide physicians, ER and ICU doctors, and psychiatrists with a comprehensive source of information and opinion on nonconvulsive status epilepticus.



Status Epilepticus Mechanisms Of Brain Damage And Treatment


Status Epilepticus Mechanisms Of Brain Damage And Treatment
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Author : Antonio V. Delgado-Escueta
language : en
Publisher: Raven Press (ID)
Release Date : 1983

Status Epilepticus Mechanisms Of Brain Damage And Treatment written by Antonio V. Delgado-Escueta and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.




Treatment Of Status Epilepticus


Treatment Of Status Epilepticus
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Author : Walter Fröscher
language : en
Publisher:
Release Date : 1979

Treatment Of Status Epilepticus written by Walter Fröscher and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.




Encephalopathy Related To Status Epilepticus During Slow Sleep


Encephalopathy Related To Status Epilepticus During Slow Sleep
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Author : Guido Rubolli
language : en
Publisher: John Libbey Eurotext
Release Date : 2019-12-05

Encephalopathy Related To Status Epilepticus During Slow Sleep written by Guido Rubolli and has been published by John Libbey Eurotext this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-05 with Medical categories.


In the last years, clinical data, neurophysiological and imaging investigations, as well as genetic studies have renewed the interest on ESES. In addition, experimental findings from sleep research have opened fascinating perspectives on some possible pathophysiological mechanisms involved in this condition. These issues are presented and discussed in this book by clinicians, neurophysiologists, sleep physiologists and geneticists. They all have been working on ESES with the aim to provide an updated overview of this special syndrome in the light of recent research.