New Findings On Aclarubicin In The Treatment Of Acute Myeloid Leukemia
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New Findings On Aclarubicin In The Treatment Of Acute Myeloid Leukemia
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Author : W. Hiddemann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
New Findings On Aclarubicin In The Treatment Of Acute Myeloid Leukemia written by W. Hiddemann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Since the introduction of new anthracycline derivatives and anthrachi none analogues a few years ago, aclacinomycin A (Aclarubicin) has become an established agent for the treatment of hematologic malig nancies. A special symposium was therefore held during the congress of the German Society of Hermatology and Oncology in Hannover in October 1989 to provide an up-to-date overv.iew. Leading experts from the United States, Sweden, and Germany reported on the results being obtained with aclacinomycin A, alone or combined with other agents, in patients with acute leukemias and myelodysplastic syndromes. This book is based on their contributions. As regards single-agent treatment, aclacinomycin A in myelodys plastic syndromes is dealt with, as well as its application in older patients with acute myeloid leukemia. Four contributions are devoted to the use of aclacinomycin A in combination with conventional or intermediate dose cytosine arabinoside or etoposide in patients with relapsed or refractory acute myeloid leukemia. The results reported indicate that aclacinomycin A has substantial activity in the treatment of hematologic malignancies. In summary, this book provides a valuable update on the current status of aclacinomycin A as used by experts in the treatment of he matologic malignancies.
New Findings On Aclarubicin In The Treatment Of Acute Myeloid Leukemia
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Author : W. Hiddemann
language : en
Publisher: Springer Verlag
Release Date : 1990-01-01
New Findings On Aclarubicin In The Treatment Of Acute Myeloid Leukemia written by W. Hiddemann and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-01-01 with Hannovre - 1989 categories.
Medicinal Chemistry Of Anticancer Drugs
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Author : Carmen Avendaño
language : en
Publisher: Elsevier
Release Date : 2015-06-11
Medicinal Chemistry Of Anticancer Drugs written by Carmen Avendaño and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-11 with Science categories.
Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature
Myelodysplastic Syndromes New Insights For The Healthcare Professional 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-10
Myelodysplastic Syndromes New Insights For The Healthcare Professional 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-10 with Medical categories.
Myelodysplastic Syndromes: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Myelodysplastic Syndromes in a concise format. The editors have built Myelodysplastic Syndromes: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Myelodysplastic Syndromes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Myelodysplastic Syndromes: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Razoxane And Dexrazoxane Two Multifunctional Agents
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Author : Walter Rhomberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-08-03
Razoxane And Dexrazoxane Two Multifunctional Agents written by Walter Rhomberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-03 with Medical categories.
Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms. They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc. The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer ́s disease could be stabilized by one or both these drugs.
National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1991
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medicine categories.
Aml In The Molecular Age From Biology To Clinical Management
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Author : Celalettin Ustun
language : en
Publisher: MDPI
Release Date : 2018-10-12
Aml In The Molecular Age From Biology To Clinical Management written by Celalettin Ustun and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-12 with Acute myeloid leukemia categories.
This book is a printed edition of the Special Issue "AML in the Molecular Age: From Biology to Clinical Management" that was published in JCM
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 2000
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medicine categories.
Cytotoxins And Immunotoxins For Cancer Therapy
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Author : Koji Kawakami
language : en
Publisher: CRC Press
Release Date : 2004-11-15
Cytotoxins And Immunotoxins For Cancer Therapy written by Koji Kawakami and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-15 with Medical categories.
Recent advances in cytotoxins and immunotoxins are accelerating our understanding of cancer and leading to more effective therapeutic treatments. Although a large number of articles have been published on these cytotoxins and immunotoxins, this important information has yet to be compiled into one comprehensive resource. For the first time,
Drug Repurposing In Neurodegenerative And Neuropsychiatric Disorders
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Author : Anna R. Carta
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-25
Drug Repurposing In Neurodegenerative And Neuropsychiatric Disorders written by Anna R. Carta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-25 with Science categories.