New Insights Into Innate Immune Cell Based Immunotherapies In Cancer
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New Insights Into Innate Immune Cell Based Immunotherapies In Cancer
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Author : Mary Poupot-Marsan
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-17
New Insights Into Innate Immune Cell Based Immunotherapies In Cancer written by Mary Poupot-Marsan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-17 with Medical categories.
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Disease Biology And Signaling
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Author : Jérôme Paggetti
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-31
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Disease Biology And Signaling written by Jérôme Paggetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-31 with Medical categories.
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Tumor Immunology And Immunotherapy
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Author : Jérôme Paggetti
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-02
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Tumor Immunology And Immunotherapy written by Jérôme Paggetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-02 with Medical categories.
Topic Editor MS received funding from Bayer AG.
Cell Based Immunotherapies For Cancer
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Author : Alok K. Mishra
language : en
Publisher: Springer Nature
Release Date : 2025-06-24
Cell Based Immunotherapies For Cancer written by Alok K. Mishra and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-24 with Medical categories.
This book explores the rapidly evolving field of cancer immunotherapy, which focuses on harnessing the immune system's power to combat cancer. As traditional treatments like chemotherapy and radiation therapy often have significant side effects and may not be effective for all cancer types, immunotherapy offers a promising alternative. Among the most notable advancements in this field are cell-based therapies, which involve modifying a patient’s own immune cells or engineering specialized cells to enhance their ability to target cancer. Key approaches include chimeric antigen receptor (CAR) T-cell therapy, tumor-infiltrating lymphocyte (TIL) therapy, and dendritic cell (DC)-based therapy. Providing a comprehensive overview of these therapies, this book explores their scientific foundations, recent developments, clinical applications, and associated challenges. It also discusses emerging immunotherapeutic strategies, the commercial landscape, and future research directions. A valuable resource for researchers, clinicians, and industry professionals involved in cancer treatment, this book also serves as an informative reference for students and academics in biology, biotechnology, immunology, and related disciplines seeking a deeper understanding of cancer immunotherapy.
New Insights Into Fibrotic Signaling In Cancer
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Author : Patrick Ming-Kuen Tang
language : en
Publisher: Frontiers Media SA
Release Date :
New Insights Into Fibrotic Signaling In Cancer written by Patrick Ming-Kuen Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
New Insights In Veterinary Cancer Immunology
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Author : Carlos Eduardo Fonseca-Alves
language : en
Publisher: Frontiers Media SA
Release Date : 2025-01-14
New Insights In Veterinary Cancer Immunology written by Carlos Eduardo Fonseca-Alves and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-14 with Science categories.
The tumour microenvironment (TME) is essential for cancer maintenance and is responsible for several antitumor characteristics, such as immune system avoidance, resistance to anticancer therapies, invasion, and metastasis. The TME is composed of several components, including fibroblasts, extracellular matrix proteins, pericytes, and immune cells. The immune cells, including T-lymphocytes, are responsible for fighting cancer cells, inducing cell death. However, cancer cells develop several mechanisms to avoid the immune system, including mutations to change the antigens originally recognised by T-cells. Tumours that can avoid the immune system, including the T-cell antitumor response, are known as nonimmunogenic tumours or “cold” tumours. The main characteristic of this tumour subtype is lack of response to immunotherapy drugs. In contrast, immunogenic, or “hot” tumours have an active T-cell antitumor response and respond well to immunotherapy. Therefore, elucidating the TME characteristics is the first step for the application in clinical practice. In recent years, there has been progress in understanding how the immune system and inflammation are associated with different cancer subtypes. In 2018, the Nobel Prize in Physiology and Medicine was awarded for the discovery of cancer therapy by the inhibition of negative immune regulation. Since then, there has been an increase in global attention directed towards the immune system and its implications for cancer therapy. Tumour progression is highly dependent of modifications in the TME, which are directly related with patient’s prognosis and present direct impacts on chemotherapy efficiency. Investigating and comprehending the TME composition during tumour progression allows new therapeutic strategies and approaches personalized to each patient. Thus, understanding its complex interactions leads to different strategies to reprogramming TME for therapeutic purposes. The main goal of this special issue is to bring together manuscripts focused on cancer immunology with a translational approach. We welcome Original Research and Review articles from investigators worldwide that will stimulate the continuing efforts to understand the interactions with tumour microenvironment, including: 1) Identification of immune cells as a prognostic factor for cancer in veterinary patients. 2) Stratification of tumour in animals according to its immunological content (hot or cold tumours) 3) Specific therapies targeting immune system components with translational potential 4) Genetic and epigenetic cancer modifications associated with the immune cells 5) Therapeutic implications of antitumor vaccines in small animals
New Insights Into Parvovirus Research
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Author : Giorgio Gallinella
language : en
Publisher: MDPI
Release Date : 2020-04-15
New Insights Into Parvovirus Research written by Giorgio Gallinella and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-15 with Medical categories.
Viruses in the Parvoviridae family constitute one of the most diverse and intriguing fields of research. While they all share an ssDNA genome and a small capsid, they can differ widely in structure, genome organization and expression, virus–cell interaction, and impact on the host. Exploring such diversity and unraveling the inherent complexity in these apparently simple viruses is an ongoing endeavor and commitment for the scientific community. The translational implications of research on parvoviruses are relevant. Within the family, some viruses are important human and veterinary pathogens, in need of diagnostic methods and antiviral strategies; other viruses have long been studied and engineered as tools for oncolytic therapy, or as sophisticated gene delivery vectors, and can now display their wide and expanding applicative potential. This Special Issue of Viruses collects recent contributions in the field of parvovirus research, with a focus on new insights and research on unresolved issues, as well as new approaches exploiting systemic methodologies. Evolution, structural biology, viral replication, virus–host interaction, pathogenesis and immunity, and viral oncotherapy are a selection of the topics addressed in the issue that can be of relevance to the community involved in parvovirus research and of interest to a wider audience.
Cancer Immunotherapies From Efficacy To Resistance Mechanisms
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Author : Morten Hansen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-29
Cancer Immunotherapies From Efficacy To Resistance Mechanisms written by Morten Hansen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-29 with Medical categories.
Dr. Koguchi receives funding from Tesaro, a GSK company, Bristol-Myers Squibb, and Shimadzu Corporation.. Dr. Vujanovic is a co-inventor of a methodology licensed to INmune Bio, Inc. where a selective inhibitor of soluble TNF can be used to prevent or treat malignancies. Dr. Hansen is the recipient of a private grant from Eurostars Eureka. The other Topic Editors declare no competing interests.
Cytotoxicity Understanding Cellular Damage And Response
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Author : Anil Sukumaran
language : en
Publisher: BoD – Books on Demand
Release Date : 2023-11-15
Cytotoxicity Understanding Cellular Damage And Response written by Anil Sukumaran and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-15 with Medical categories.
In the dynamic world of cellular biology, the intricate dance of life and death plays out through the lens of cytotoxicity. Delve deep into cellular responses’ mysteries, where threats and defenses wage a microscopic war, influencing the broader landscape of health and disease. This authoritative volume on cytotoxicity encapsulates the breadth and depth of current knowledge, illuminating pathways that have been meticulously charted and those yet to be discovered. Each chapter, penned by experts in the field, unveils the molecular intricacies, external triggers, and translational potential of understanding cellular damage. Key Highlights: •Comprehensive explorations of molecular mechanisms •Cutting-edge methodologies in cytotoxic research •Insight into the profound implications for drug development and disease therapeutics Whether you are a seasoned researcher, an aspiring scientist, or an avid learner, this book promises to challenge, enlighten, and inspire. As the boundary between known territories and uncharted frontiers blurs, Cytotoxicity - Understanding Cellular Damage and Response is your definitive guide to a world where cellular responses hold the keys to groundbreaking discoveries. This book is an indispensable resource for anyone eager to navigate the complexities of cell damage and defense. Join us on a journey into the cellular realm, where every page turns a new chapter in understanding, innovation, and hope.
The Intricate Innate Immune Cancer Cell Relationship In The Context Of Tumor Angiogenesis Immunity And Microbiota The Angiogenic Switch In The Tumor Microenvironment As A Key Target For Immunotherapies
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Author : Lorenzo Mortara
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-15
The Intricate Innate Immune Cancer Cell Relationship In The Context Of Tumor Angiogenesis Immunity And Microbiota The Angiogenic Switch In The Tumor Microenvironment As A Key Target For Immunotherapies written by Lorenzo Mortara and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-15 with Medical categories.