New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Tumor Immunology And Immunotherapy
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New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Tumor Immunology And Immunotherapy
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Author : Jérôme Paggetti
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-02
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Tumor Immunology And Immunotherapy written by Jérôme Paggetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-02 with Medical categories.
Topic Editor MS received funding from Bayer AG.
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Disease Biology And Signaling
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Author : Jérôme Paggetti
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-31
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Disease Biology And Signaling written by Jérôme Paggetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-31 with Medical categories.
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Prognostic And Predictive Biomarkers And Therapy
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Author : Jérôme Paggetti
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-23
New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Prognostic And Predictive Biomarkers And Therapy written by Jérôme Paggetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-23 with Medical categories.
Advances In Tumor Immunology And Immunotherapy
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Author : Joseph D. Rosenblatt
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-25
Advances In Tumor Immunology And Immunotherapy written by Joseph D. Rosenblatt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-25 with Medical categories.
Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon response pathways, and NKG2D downregulation have all provided new insight into suppression of anti-tumor immunity and tumor evasion. In addition to emerging understanding of tumor evasion, new immune targets such as CTLA4 blockade, NK stimulatory receptors, manipulation of the antigen processing and presentation, cytokine and costimulatory responses all provide new possibilities for enhancing anti-tumor immunity even in tumors previously felt to be resistant to immune attack. Several of these strategies have already been realized in the clinic. The volume will explore evolving paradigms in antigen presentation, dendritic cell biology, the innate response and immunosuppressive mechanisms, and emerging strategies for manipulation of the immune system for therapeutic benefit that have realized success in neuroblastoma, leukemia, melanoma, lung cancer, and allogeneic transplantation. Early successes as well as failures will be highlighted to provide a snapshot of the state of clinical immunotherapy with an eye to future possibilities such as combination therapies, adoptive T-cell transfer, and the retargeting of immune cells via T-cell receptor engineering.
New Insights Into Innate Immune Cell Based Immunotherapies In Cancer
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Author : Mary Poupot-Marsan
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-17
New Insights Into Innate Immune Cell Based Immunotherapies In Cancer written by Mary Poupot-Marsan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-17 with Medical categories.
Hiv And Cancer Immunotherapy Similar Challenges And Converging Approaches
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Author : Mirko Paiardini
language : en
Publisher: Frontiers Media SA
Release Date : 2020-05-15
Hiv And Cancer Immunotherapy Similar Challenges And Converging Approaches written by Mirko Paiardini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-15 with categories.
Complexity Of Tumor Microenvironment A Major Culprit In Cancer Development
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Author : Ihtisham Bukhari
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-04
Complexity Of Tumor Microenvironment A Major Culprit In Cancer Development written by Ihtisham Bukhari and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-04 with Medical categories.
Systemic Immune Dysregulation In Malignant Disease Insights Monitoring And Therapeutic Exploitation
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Author : Petros Christopoulos
language : en
Publisher: Frontiers Media SA
Release Date :
Systemic Immune Dysregulation In Malignant Disease Insights Monitoring And Therapeutic Exploitation written by Petros Christopoulos and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
Tumor Microenvironment
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Author : Peter P. Lee
language : en
Publisher: Springer Nature
Release Date : 2020-03-25
Tumor Microenvironment written by Peter P. Lee and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-25 with Medical categories.
This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self. Checkpoint inhibitor therapy is now an accepted new form of cancer treatment. Other immuno-oncology approaches, such as adoptive cell therapy and metabolic inhibitors, have also shown promising results for specific indications. Immune resistance is common, however, limiting the efficacy of immunotherapy in many common cancer types. The reasons for such resistance are diverse and peculiar to the immune landscapes of individual cancers, and to the treatment modality used. Accordingly, approaches to circumvent resistance need to take into account context-specific genetic, biological and environmental factors that may affect the cancer immune cycle, and which can best be understood by studying the target tissue and correlated systemic immune markers. Understanding the major requirements for the evolutionary process governing human cancer growth in the immune-competent host will guide effective therapeutic choices that are tailored to the biology of individual cancers.
Bioinformatics Analysis Of Omics Data For Biomarker Identification In Clinical Research
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Author : Lixin Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-10
Bioinformatics Analysis Of Omics Data For Biomarker Identification In Clinical Research written by Lixin Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-10 with Science categories.