New Research On Signal Transduction
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Signal Transduction Pathways Mechanisms And Diseases
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Author : Ari Sitaramayya
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-02
Signal Transduction Pathways Mechanisms And Diseases written by Ari Sitaramayya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-02 with Science categories.
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Signal Transduction
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Author : Bastien D. Gomperts
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002-03-08
Signal Transduction written by Bastien D. Gomperts and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-08 with Medical categories.
Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. - Coherent, precise text providing insight in depth to a subject that is central to cell biology and fundamental to many areas of biomedicine - Extensive conceptual colour artwork assists with the comprehension of key topics - Extensive referencing provides an invaluable link to the core and historical literature - Margin notes highlighting milestones in the evolution of our understanding of signalling mechanisms
Cellular Signal Processing
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Author : Friedrich Marks
language : en
Publisher: Garland Science
Release Date : 2017-05-17
Cellular Signal Processing written by Friedrich Marks and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-17 with Medical categories.
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
New Research On Signal Transduction
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Author : Bruce R. Yanson
language : en
Publisher: Nova Publishers
Release Date : 2007
New Research On Signal Transduction written by Bruce R. Yanson and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. In such cases the chain of steps is referred to as a "signalling cascade" or a "second messenger pathway" and often results in a small stimulus eliciting a large response. Hormones and other signalling molecules may exit the sending cell by exocytosis or other means of membrane transport. The sending cell is typically of a specialised type. Its recipients may be of one type or several, as in the case of insulin, which triggers diverse and systemic effects. This book sheds new light in this exciting field of cell transportation research.
Signal Transduction
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Author : Lewis C. Cantley
language : en
Publisher:
Release Date : 2014-05-31
Signal Transduction written by Lewis C. Cantley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-31 with Science categories.
"This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. It first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function"--
Tissue Specific Cell Signaling
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Author : Joana Vieira Silva
language : en
Publisher: Springer
Release Date : 2020-05-30
Tissue Specific Cell Signaling written by Joana Vieira Silva and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-30 with Medical categories.
Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Signal Transduction In The Retina
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Author : Steven J. Fliesler
language : en
Publisher: CRC Press
Release Date : 2007-12-26
Signal Transduction In The Retina written by Steven J. Fliesler and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-26 with Medical categories.
In the twenty-first century, we are just beginning to understand more clearly the enormous diversity and complexity of signaling processes in the retina. Integrating advances in the biochemistry, cell biology, physiology, and physics of phototransduction, Signal Transduction in the Retina presents the methodologies and experimental approache
New Research On Alcoholism
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Author : Douglas R. Baye
language : en
Publisher: Nova Publishers
Release Date : 2007
New Research On Alcoholism written by Douglas R. Baye and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Alcoholism is a disorder characterised by the excessive consumption of and dependence on alcoholic beverages, leading to physical and psychological harm and impaired social and vocational functioning. This book gathers new and important research on this socially and medically destructive disorder. These include addiction issues, forms of treatment, behavioural and clinical studies.
New Developments In Metastasis Suppressor Research
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Author : Paul Jackson
language : en
Publisher: Nova Publishers
Release Date : 2007
New Developments In Metastasis Suppressor Research written by Paul Jackson and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
The spread of cancer cells from their organ of origin to distant tissues is called metastasis. Cancer metastasis is the main cause of death from cancer, and in many cases is difficult to detect or treat. The process by which tumour cells become metastatic is complex and involves many stages, including detachment of cells from the main tumour mass, degradation of the surrounding extra-cellular matrix, invasion into nearby blood vessels, travel and survival through the circulatory system, attachment to a vessel wall, extra-vasation, degradation of the extra-cellular matrix into a distant tissue/organ, and the development of a novel blood supply. In order to accomplish this process, the cells acquire characteristics which are important for each stage. Recently, a class of genes known as metastasis suppressors' has been the subject of intense investigation. For some metastasis suppressor genes, there is strong evidence from both in vitro and in vivo studies to demonstrate key roles in the metastatic process, for others data is much more limited, and their importance uncertain. In this book, chapters are devoted to providing up-to-date summaries of our understanding of individual metastasis suppressor genes. Each is written by a leading authority in the study of that gene. Topics covered include discussions on how each metastasis suppressor was discovered, the mechanisms underlying their loss of expression in tumours and tumour cell lines, their proposed molecular functions, and the consequences to a tumour cell of the loss of this function. This compilation aims to provide, in a single volume, comprehensive information that will be valuable to all scientists working in cancer research, to students needing to understand molecular events that regulate tumour progression and the acquisition of metastasis, and to clinicians who might wish to know more of the roles of potentially new markers for cancer diagnosis and prognosis.
New Trends In Macromolecular And Supramolecular Chemistry For Biological Applications
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Author : Marc J.M. Abadie
language : en
Publisher: Springer Nature
Release Date : 2021-05-26
New Trends In Macromolecular And Supramolecular Chemistry For Biological Applications written by Marc J.M. Abadie and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-26 with Medical categories.
This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.