New Techniques For Studying Biomembranes
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New Techniques For Studying Biomembranes
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Author : Qiu-Xing Jiang
language : en
Publisher: CRC Press
Release Date : 2020-03-18
New Techniques For Studying Biomembranes written by Qiu-Xing Jiang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-18 with Medical categories.
New Techniques for Studying Biomembranes describes some of the latest methods used to investigate the dynamic distribution of specific lipids in membranes and their effects on other membrane components. The contributors present important discoveries with respect to lipid analysis and lipid interactions with membrane proteins. Various methods, which have been used to study lipid bilayer structure and lipid organization in membranes, include both in vitro and in vivo membrane systems, and study membrane proteins in various membrane systems. Key Features: Reviews both in vivo and in vitro analytical technologies and methods for studying membrane structure and function Explores how lipid bilayers and membrane proteins interact Includes contributions from an international team of researchers actively studying membrane structure and function Identifies various diseases whose causes are related to membrane proteins Related Titles: Christopher R. Jacobs, Hayden Huang, and Ronald Y. Kwon. Introduction to Cell Mechanics and Mechanobiology (ISBN 978-0-8153-4425-4) Wendell Lim and Bruce Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Stephen Rothman. Proteins Crossing Membranes: A Scientist’s Memoir (978-0-3670-7449-4)
Biomembrane Structures
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Author : Parvez I. Haris
language : en
Publisher: IOS Press
Release Date : 1998
Biomembrane Structures written by Parvez I. Haris and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medical categories.
Biological membranes play a significant role in a range of biological processes such as ion-transport and signal transduction. Over the years much effort has been devoted towards developing an understanding of biomembrane structure. The study of this subject is now reaching an important stage. This is because at last the full three-dimensional structure of certain membrane proteins is beginning to be resolved. In the past three-dimensional structures of membrane proteins were difficult to obtain as only two dimensional crystals were available. In recent years satisfactory crystals have been obtained and X-ray diffraction techniques have been applied. This has led to the three dimensional structures of the photosynthetic reaction centres, porins and more recently the structure of cytochrome oxidase. Of course not all membrane proteins are readily crystallisable and some are not even available in sufficient quantities to obtain the necessary crystals or to carry out biophysical experiments. In some cases e.g. the voltage-gated potassium ion channel membrane proteins their structure has been proposed mainly on the basis of molecular biology methods. This has prompted the search for alternative approaches for characterising biomembrane structure. Molecular biological studies are providing a wealth of information on a number of different membrane proteins. Combining the information derived from such studies with molecular modelling is becoming extremely useful for relating structure to function. Development of other approaches include synthesis and structure- function analysis of peptides corresponding to functionally important domains of membrane proteins. This book presents a series of Chapters discussing how a combination of molecular biological, biophysical and theoretical (molecular modelling) techniques are helping us to obtain a much clearer picture of biomembrane structure. After an introductory Chapter on the Principles of membrane Protein Structure, the book is divided into two sections; one dealing with crystallographic approaches and the other non-crystallographic approaches such as NMR, AFM, SPR and FTIR spectroscopy. Chapters dealing with the recently solved crystal structure of cytochrome oxidase and bacteriorhodopsin are presented. The book contains contributions from leading membrane scientists describing their latest studies. It provides an up to date coverage of the developments in the field of biomembranes with particular emphasis on membrane proteins.
New Techniques For Studying Biomembranes
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Author : Taylor & Francis Group
language : en
Publisher: CRC Press
Release Date : 2021-12-13
New Techniques For Studying Biomembranes written by Taylor & Francis Group and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-13 with categories.
This book describes methods used to investigate the function and distribution of lipids in membranes. Contributors present discoveries that have to do with lipid analysis and lipid interactions with other components of membranes, such as proteins, receptors, transporters and ion channels.
Biomembranes
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Author : Robert B. Gennis
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Biomembranes written by Robert B. Gennis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermody namics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases, the availability of texts in active research areas should help stimulate the creation of new courses.
Biofunctional Membranes
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Author : D.A. Butterfield
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Biofunctional Membranes written by D.A. Butterfield and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Science categories.
''Interesting with many useful ideas and references. It covers a broad range and it is a good introduction to this field.'' ---Analyst
Nasa Technical Memorandum
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Author : United States. National Aeronautics and Space Administration
language : en
Publisher:
Release Date : 1992
Nasa Technical Memorandum written by United States. National Aeronautics and Space Administration and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Aeronautics categories.
Methods In Membrane Biology
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Author : Edward D. Korn
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21
Methods In Membrane Biology written by Edward D. Korn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Science categories.
The contributions of electron microscopy to membrane biology have been indispensable and, at the same time, disappointing. Membranes were known to exist before the advent of electron microscopy and general principles of their composition and molecular organization had been deduced from permeability and electrical conductivity measurements, polarized light microscopy, and X-ray diffraction. On the other hand, the complexities of the many intracellular membranes and membranous organelles were really not suspected until they were observed by the electron microscopist. One then had further hopes that the high resolution of the electron microscope (theoretically it can resolve atomic distances) would allow the visualization of the molecular architecture of membranes and lead directly to an under standing of structure and function at the molecular level. This expectation has been largely unrealized. Because of the great difficulties encountered in the preparation of biological material, because of the uncertainty of the chemistry of "staining," and because of numerous electron optical artifacts, it has been a major challenge just to rationalize the observed images in terms of the known facts, let alone to utilize the images to expand our knowledge of the molecular structure of biological membranes. The many differences among membranes with respect to function and composition are lost in the universal trilamellar image. Perhaps the one major exception to this, and the major structural contribution of electron microscopy at the molecular level, has come from freeze-etch electron microscopy.
Drug Biomembrane Interaction Studies
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Author : Rosario Pignatello
language : en
Publisher: Elsevier
Release Date : 2013-10-31
Drug Biomembrane Interaction Studies written by Rosario Pignatello and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with Medical categories.
The design and development of drugs and new pharmaceutical formulations require a full characterization of the chemical and physicochemical events occurring at the level of the single active ingredients or excipients, as well as their reciprocal interaction. Thermal analysis techniques are among the most widely used methods to achieve this; among them, the Differential Scanning Calorimetry (DSC) technique, in which the thermotropic behaviour of a single substance or mixtures is analyzed as a function of a controlled temperature program. DSC is an accurate and rapid thermo-analytical technique, widely used by the pharmaceutical industry and in drug research to investigate several physico-chemical phenomena, such as polymorphism, melting and crystallization, purity, and drug-excipient interaction; as well as characterizing biomolecules such as genetic material.Drug-biomembrane interaction studies is written by scientists renowned for their work in the field of DSC applications to drug development and delivery, and especially to drug-biomembrane interaction studies. The book combines insights from biochemistry and physiology with those from structural biology, nanotechnology and biothermodynamics, to obtain a complete depiction of cell membranes and their functions. - Summarizes and updates the recent development in a unique handbook format - Consists of a combination of scientific updates within the field - Contains chapters written by some of the highest-level experts in the field of DSC
Progress In Membrane Biotechnology
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Author : Chapman
language : en
Publisher: Birkhäuser
Release Date : 2013-03-08
Progress In Membrane Biotechnology written by Chapman and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Social Science categories.
It is well known that basic science can trigger an invention of considerable technological and commercial importance. Indeed basic science and invention are often inextricably linked, each being able to catalyse the other. To engender such developments it is important that there should be good communication between the scientist and the technologist. The field of membrane biotechnology is a growing field where such communication is increasingly taking place and where new inventions are occurring. This book provides an overview of this developing field. It contains chapters by scientist and technologists working in the field of Membrane Biotechnology. The chapters cover the latest advances in basic science as well as some recent technological applications. The basic topics include the application of dynamic X-ray diffraction to lipid water systems, FTIR spectroscopy applied to membrane proteins, fluorescent analogues of phosphoinositides, studies of platelet activating factor, antibody binding to model membranes and phospholipase C induced fusion. The technological topics described include the development of new haemocompatible materials based upon biomembrane mimicry, new lung surfactant materials, drug delivery systems including liposomes and the development of new biosensors including Langmuir Blodgett films. The meeting showed that there are many other useful applications in the pipeline. The potential for new polymeric drug delivery systems, of ion selective systems based on the knowledge of ion-channel protein structures, of new plastics for cell growth and cellular engineering for artificial organs. These are among the interesting developments that are emerging in this field.
Drug Biomembrane Interaction Studies
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Author : R. Pignatello
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-10-31
Drug Biomembrane Interaction Studies written by R. Pignatello and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with Technology & Engineering categories.
DSC studies of the interaction between drugs or other biologically active compounds with biomembrane models has often been associated or integrated with other analytical methodologies. The information gained from various techniques can depict the different and complex elements that compose such interactions. This chapter will summarize some recent examples of successfully combining DSC with other physico-chemical methods, such as spectroscopy, chromatography, calorimetry, the Langmuir–Blodgett film technique and microscopy.