Nitric Oxide
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Nitric Oxide
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Author : Louis J. Ignarro
language : en
Publisher: Academic Press
Release Date : 2000-09-13
Nitric Oxide written by Louis J. Ignarro and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-09-13 with Science categories.
Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide Authored by world experts on nitric oxide Includes an overview of basic principles of biology and chemical biology Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense
Nitric Oxide
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Author : Louis J. Ignarro
language : en
Publisher: Academic Press
Release Date : 2009-11-05
Nitric Oxide written by Louis J. Ignarro and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-05 with Science categories.
Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide’s role as a principal neurotransmitter moderating erectile function, a pathophysiological negotiator and messenger in inflammation, and a weapon against infections have increased research attention across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. Edited by Nobel Laureate Louis J. Ignarro Up-to-date therapeutic implications of nitric oxide research Authored by world experts on nitric oxide Detailed research of the biochemistry and synthesis of nitric oxide
Nitric Oxide
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Author : Jack Lancaster, Jr.
language : en
Publisher: Elsevier
Release Date : 1996-07-27
Nitric Oxide written by Jack Lancaster, Jr. and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-27 with Science categories.
This unique sourcebook serves as a comprehensive reference, bridging the well-established chemistry of nitric oxide and the new and exciting role of nitric oxide as an effector and signaling molecule in numerous biological systems. Nitric Oxide: Principles and Actions relates the chemical properties of the molecule to its possible effects on biological systems, under both normal physiological and pathophysiological conditions. Combining the chemistry and analysis of nitric oxide with newer studies of the relevance of the molecule gives this book a long life, making it extremely useful to researchers in a number of areas. Provides a much needed compilation of what is known about nitric oxide and its properties Enables researchers to understand the importance and use of nitric oxide in systems of study Covers an area of tremendous growth in research Provides the first collection of the roles of nitric oxide in microbial and mammalian systems and as a probe of metalloenzymes Presents the historically important role of nitric oxide in food preservation
Life Death And Nitric Oxide
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Author : Anthony R Butler
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31
Life Death And Nitric Oxide written by Anthony R Butler and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Science categories.
Designated 'Molecule of the Year' in 1992 in recognition of its many biological roles, nitric oxide has wide significance in the world around us and the story of nitric oxide is still unfolding. This small and seemingly innocent molecule has for many years been known to play a significant role in both the creation of photochemical smogs and in the nitrogen cycle. It has an interesting chemistry as a metal ligand, and the bonding within the nitric oxide molecule has been extensively studied. More recently, the molecule has been in the spotlight for the role it plays in controlling blood flow, in the immune system and in brain activity. Life, Death and Nitric Oxide covers many of the topics relating to nitric oxide, from smog and catalytic converters to tumour growth, blood flow and Viagra, with the aim of finding out why such a simple molecule can do so much.
The Haemodynamic Effects Of Nitric Oxide
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Author : Robert T Mathie
language : en
Publisher: World Scientific
Release Date : 1999-08-30
The Haemodynamic Effects Of Nitric Oxide written by Robert T Mathie and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-08-30 with Science categories.
Since the discovery of nitric oxide as an endothelium-derived relaxing factor in 1987, investigations on its precise modes of action have been carried out at an extraordinary rate. Nitric oxide is now implicated in many physiological and pathological processes — not just in the control of vascular resistance, but in nerve transmission, cell proliferation, inflammatory responses and so on. Despite such rapid progress, no attempt has been made to combine the current knowledge of this subject matter in a single textbook. This volume has been written with the above in mind and presents a topical, comprehensive overview of the biochemistry and the physiological and pathophysiological effects of nitric oxide as they relate to the cardiovascular system. The therapeutic implications of nitric oxide are also considered. The text comprises contributions from many of the leading international authorities on the topic including Professor L J Ignarro, winner of the 1998 Nobel Prize in Physiology or Medicine. Contents:Physiology and Biochemistry of Nitric Oxide:Chemistry and Molecular Biology of Nitric Oxide Synthesis (A J Hobbs & L J Ignarro)Nitric Oxide Synthases Biology: Insights Gained from ‘Knockout’ Mice (A Papapetropoulos et al.)Inhibitors of Nitric Oxide Biosynthesis (G J Southan et al.)Peripheral Vascular Effects of Nitric Oxide:The Role of Nitric Oxide in Cerebrovascular Regulation and Stroke (C Iadecola)The Physiological and Pathophysiological Effects of Nitric Oxide in the Coronary Circulation (P Groves)The Effect of Nitric Oxide on Myocardial Function and Dysfunction (B D Prendergast & A M Shah)Clinical Implications of Nitric Oxide:Oxidative Tissue Injury, Nitric Oxide and Atherosclerosis (R P Patel et al.)Endothelial Dysfunction Associated with Cardiovascular Disease and Transplantation (G J Dusting & A M Dart)The Role and Therapeutic Implications of Nitric Oxide in Systemic Hypertension (P Forte & N Benjamin)and other papers Readership: Students and researchers in physiology, biochemistry and clinical methods/ laboratory medicine. Keywords:Endothelium;Vascular Smooth Muscle;Nitric Oxide Synthase;Nitrovasodilator;Shear Stress;Atherosclerosis;Hypertension;Septic Shock;Microcirculation;Coronary Circulation;Cerebal Circulation;Renal Circulation;Hepatic Circulation;Intestinal Circulation
Nitric Oxide In Health And Disease
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Author : Jill Lincoln
language : en
Publisher: Cambridge University Press
Release Date : 1997-08-28
Nitric Oxide In Health And Disease written by Jill Lincoln and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-08-28 with Medical categories.
Nitric oxide has a tantalizing role in health and disease: while many of its wide-ranging effects are well known, there remains much more to explore and to learn about the interactions of this fascinating molecule in physiological and pathophysiological processes. The volume reviews the myriad effects of nitric oxide as a chemical messenger in the central nervous system, peripheral nervous system, immune system and cardiovascular system. Furthermore, it provides a very practical introduction to the procedures and experimental protocols necessary to work with and study nitric oxide and its synthesizing enzyme, nitric oxide synthase, in the laboratory. In this respect the volume is unique, providing as it does a complete single-volume review of the role of nitric oxide in health and disease, and a very practical introduction to the methods and protocols involved in this intriguing and active area of biomedical research.
Biochemical Pharmacological And Clinical Aspects Of Nitric Oxide
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Author : N. Allon
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biochemical Pharmacological And Clinical Aspects Of Nitric Oxide written by N. Allon and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
A decade ago, for most scientists investigating various issues in life sciences the word "NO" was used in a negative context. It is astounding to observe how recently researchers are addressing the issue of NO, namely, nitric oxide, in over fifty publications weekly. Science journal, while naming nitric oxide: "Molecule of the Year" (December 1992), said it all: "NO news is good news. " For a long period of time NO was considered as a pollutant and every ecology minded person tried to eliminate it. It was the discovery of NO involvement in the process of host killing by macrophages and several years later the finding that EDRF is none else but NO, that promoted this field. Nitric oxide's major role in the control of blood pressure is merely one factor of an extensive list of effects and functions attributed to it. NO is implicated in long-term potentiation (LPT), a principal process involved in memory consolidation and it is considered as the main biochemical substance responsible for penile erection. It should be noted that additional roles for NO are discovered continuously as many laboratories join the quest for the mystery of this small molecule. The observation that NO is involved in various biological processes is not unique, as other second messengers (i. e. , cyclic AMP), participate in a diverse set of functions.
Functional Nitric Oxide Nutrition
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Author : Nathan S Bryan Phd
language : en
Publisher: Crescendo Publishing, LLC
Release Date : 2018-05
Functional Nitric Oxide Nutrition written by Nathan S Bryan Phd and has been published by Crescendo Publishing, LLC this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05 with categories.
This book describes the role of nitric oxide in health and disease. Nitric oxide is one of the most important molecules produced by humans and is considered the "Holy Grail" in cardiovascular medicine. Loss of nitric oxide production is what leads to chronic disease. Without healthy NO (Nitric Oxide) levels you cannot be healthy and prevent the diseases of aging. Nitric oxide is the secret to anti-aging. This book reveals the latest scientific and medical information so that readers can understand the importance of nitric oxide for optimal health. This eye-opening book teaches how the body makes NO, what goes wrong in people that can't make NO, and perhaps most importantly, how to restore production of this "miracle molecule."
Pathophysiology And Clinical Applications Of Nitric Oxide
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Author : Gabor M. Rubanyi
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Pathophysiology And Clinical Applications Of Nitric Oxide written by Gabor M. Rubanyi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Science categories.
Research on the key mediator nitric oxide has increased exponentially over the last ten years. It is now clear that, in addition to its role within the cardiovascular system, this mediator is also implicated in the normal physiological function and disease pathology of several organs and systems. A number of the fundamental research observations are now being developed into therapeutic principles and these are being pursued through clinical trials. This is the first work summarizing, in its two volumes, the quantum leap from basic science to clinical applications emerging from this decade of research.
Nitric Oxide And The Regulation Of The Peripheral Circulation
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Author : Philip J. Kadowitz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Nitric Oxide And The Regulation Of The Peripheral Circulation written by Philip J. Kadowitz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.