Nitroglycerin
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Nitroglycerin 9
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Author : Thomas Meinertz
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-10-12
Nitroglycerin 9 written by Thomas Meinertz and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-12 with Medical categories.
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Nitroglycerin 6
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Author : H. Roskamm
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-07-22
Nitroglycerin 6 written by H. Roskamm and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-22 with Medical categories.
No detailed description available for "Nitroglycerin 6".
Nitroglycerin 8
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Author : H. C. Mehmel
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-10-12
Nitroglycerin 8 written by H. C. Mehmel and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-12 with Medical categories.
No detailed description available for "Nitroglycerin 8".
The Behavior Of Nitroglycerin When Heated
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Author : Walter Otheman Snelling
language : en
Publisher:
Release Date : 1912
The Behavior Of Nitroglycerin When Heated written by Walter Otheman Snelling and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1912 with Nitroglycerin categories.
Nitroglycerin 5
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Author : Bodo E. Strauer
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-10-08
Nitroglycerin 5 written by Bodo E. Strauer and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-08 with Medical categories.
No detailed description available for "Nitroglycerin 5".
Organic Nitrates
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Author : P. Needleman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Organic Nitrates written by P. Needleman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.
Nitro Glycerine As A Remedy For Angina Pectoris
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Author : William Murrell
language : en
Publisher:
Release Date : 1882
Nitro Glycerine As A Remedy For Angina Pectoris written by William Murrell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1882 with Angina pectoris categories.
Nitroglycerin 8
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Author : Helmuth C. Mehmel
language : en
Publisher:
Release Date : 1996
Nitroglycerin 8 written by Helmuth C. Mehmel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.
Nitroglycerin 5
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Author : Bodo-Eckehard Strauer
language : en
Publisher: Walter De Gruyter Incorporated
Release Date : 1987
Nitroglycerin 5 written by Bodo-Eckehard Strauer and has been published by Walter De Gruyter Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
Nitroglycerin Sustained Release Tablet Formulation Design And Evaluation
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Author : Subrata Bhadra
language : en
Publisher: GRIN Verlag
Release Date : 2013-08-07
Nitroglycerin Sustained Release Tablet Formulation Design And Evaluation written by Subrata Bhadra and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-07 with Medical categories.
Master's Thesis from the year 2010 in the subject Medicine - Pharmacology, Pharmacy, University of Dhaka (M. Pharm, in Pharmaceutical Technology), language: English, abstract: The aim of the present studies was to develop and characterize 2.6 mg sustained release matrix tablets of Nitroglycerin. Tablets were prepared by direct compression method. Methocel K15M CR and Methocel K100LV CR polymers were used as rate retarding agents in nine formulations (F-1 to F-9). The granules were evaluated for angle of repose, loose bulk density, tapped bulk density, Carr’s index, Hausner ratio, moisture content, total porosity and assay. The tablets were subjected to diameter, thickness, assay, uniformity of content, assay after 1Month at 40°C+75%RH, hardness, friability, and in vitro dissolution studies. The granules showed satisfactory flow properties, compressibility, and drug content. All the tablet formulations showed acceptable pharmacotechnical properties and complied with pharmacopoeial specifications for tested parameters. The in vitro dissolution study was carried out for 8 hour using USP-2009 Apparatus-I (Rotating basket method) in distilled water as the dissolution medium. The release mechanisms were explored and explained by Zero order, First order, Higuchi, Korsmeyer-Peppas and Hixson-Crowell equations. Nine formulations were prepared by using three variable ratio of two polymers; Methocel K15M CR (25%, 20% and 15%) and Methocel K100LV CR (15%, 10% and 5%) where all the formulations (F-1 to F-9) contained 0.5% colloidal silicon dioxide and 1% magnesium stearate. Among these nine formulations, six formulations; F-2 (Methocel K15M CR: Methocel K100LV CR = 25% : 10%), F-3 (Methocel K15M CR : Methocel K100LV CR = 25% : 5%), F-4 (Methocel K15M CR : Methocel K100LV CR = 20% : 15%) F-5 (Methocel K15M CR: Methocel K100LV CR = 20% : 10%), F-6 (Methocel K15M CR : Methocel K100LV CR = 20% : 5%) and F-7 (Methocel K15M CR : Methocel K100LV CR = 15% : 15%) met the official specification of release profile. It was also found that the type and the amount of polymers significantly affect the time required for 50% (T50% or MDT) of drug release, release rate constant and diffusion exponent. Higher the MDT value indicates a higher drug retaining capacity of the polymers and vice-versa. Kinetic modeling of in vitro dissolution profiles revealed the drug release mechanism of all proposed formulations followed anomalous type or non-Fickian transport (n>0.43 and n