Nitroglycerin 6


Nitroglycerin 6
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Nitroglycerin 6


Nitroglycerin 6
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Author : H. Roskamm
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-07-22

Nitroglycerin 6 written by H. Roskamm and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-22 with Medical categories.


No detailed description available for "Nitroglycerin 6".



Organic Nitrates


Organic Nitrates
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Author : P. Needleman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Organic Nitrates written by P. Needleman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.



Nitroglycerin Sustained Release Tablet Formulation Design And Evaluation


Nitroglycerin Sustained Release Tablet Formulation Design And Evaluation
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Author : Subrata Bhadra
language : en
Publisher: GRIN Verlag
Release Date : 2013-08-07

Nitroglycerin Sustained Release Tablet Formulation Design And Evaluation written by Subrata Bhadra and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-07 with Medical categories.


Master's Thesis from the year 2010 in the subject Medicine - Pharmacology, Pharmacy, University of Dhaka (M. Pharm, in Pharmaceutical Technology), language: English, abstract: The aim of the present studies was to develop and characterize 2.6 mg sustained release matrix tablets of Nitroglycerin. Tablets were prepared by direct compression method. Methocel K15M CR and Methocel K100LV CR polymers were used as rate retarding agents in nine formulations (F-1 to F-9). The granules were evaluated for angle of repose, loose bulk density, tapped bulk density, Carr’s index, Hausner ratio, moisture content, total porosity and assay. The tablets were subjected to diameter, thickness, assay, uniformity of content, assay after 1Month at 40°C+75%RH, hardness, friability, and in vitro dissolution studies. The granules showed satisfactory flow properties, compressibility, and drug content. All the tablet formulations showed acceptable pharmacotechnical properties and complied with pharmacopoeial specifications for tested parameters. The in vitro dissolution study was carried out for 8 hour using USP-2009 Apparatus-I (Rotating basket method) in distilled water as the dissolution medium. The release mechanisms were explored and explained by Zero order, First order, Higuchi, Korsmeyer-Peppas and Hixson-Crowell equations. Nine formulations were prepared by using three variable ratio of two polymers; Methocel K15M CR (25%, 20% and 15%) and Methocel K100LV CR (15%, 10% and 5%) where all the formulations (F-1 to F-9) contained 0.5% colloidal silicon dioxide and 1% magnesium stearate. Among these nine formulations, six formulations; F-2 (Methocel K15M CR: Methocel K100LV CR = 25% : 10%), F-3 (Methocel K15M CR : Methocel K100LV CR = 25% : 5%), F-4 (Methocel K15M CR : Methocel K100LV CR = 20% : 15%) F-5 (Methocel K15M CR: Methocel K100LV CR = 20% : 10%), F-6 (Methocel K15M CR : Methocel K100LV CR = 20% : 5%) and F-7 (Methocel K15M CR : Methocel K100LV CR = 15% : 15%) met the official specification of release profile. It was also found that the type and the amount of polymers significantly affect the time required for 50% (T50% or MDT) of drug release, release rate constant and diffusion exponent. Higher the MDT value indicates a higher drug retaining capacity of the polymers and vice-versa. Kinetic modeling of in vitro dissolution profiles revealed the drug release mechanism of all proposed formulations followed anomalous type or non-Fickian transport (n>0.43 and n



Nitroglycerin 7


Nitroglycerin 7
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Author : P. G. Hugenholtz
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-07-08

Nitroglycerin 7 written by P. G. Hugenholtz and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-08 with Medical categories.


No detailed description available for "Nitroglycerin 7".



Cumulated Index Medicus


Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1997

Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medicine categories.




Nitroglycerin 5


Nitroglycerin 5
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Author : Bodo E. Strauer
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-10-08

Nitroglycerin 5 written by Bodo E. Strauer and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-08 with Medical categories.


No detailed description available for "Nitroglycerin 5".



Bulletin


Bulletin
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Author :
language : en
Publisher:
Release Date : 1920

Bulletin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1920 with Mines and mineral resources categories.




Early Interventions In Acute Myocardial Infarction


Early Interventions In Acute Myocardial Infarction
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Author : Elliot Rapaport
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Early Interventions In Acute Myocardial Infarction written by Elliot Rapaport and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Our understanding of the pathophysiology of acute myocardial infarction has grown enormously in recent years. This has led to an increasingly aggressive approach to management, designed to blunt the extent of infarction by salvaging acutely ischemic myocardium. Alternatives now include throm bolysis, PTCA with and without prior thrombolysis, and emergency bypass surgery, as well as the more aggressive use of a variety of drugs. This book consists of a series of chapters by experienced cardiologists and cardiovascular surgeons that present today's state of the art in managing acute myocardial infarction. It is written with the purpose of presenting practical approaches of value to the clinician related to the more complex problems faced in dealing with patients undergoing myocardial infarction. xi EARLY INTERVENTIONS IN ACUTE MYOCARDIAL INFARCTION 1. MANAGEMENT OF ARRHYTHMIAS IN THE CORONARY CARE UNIT NORA GOLDSCHLAGER, RODERICK WOODS, AND NEAL BENOWITZ With the advent of coronary care units, mortality from cardiac arrhythmias occurring during acute myocardial infarction has been unquestionably and dramatically reduced. In addition, continuous electrocardiographic monitoring has resulted in the recognition of specific arrhythmias related to acute ischemic heart disease and thus to the development of appropriate strategies for their management. This chapter will review certain specific aspects of those bradyarrhythmias and atrial and ventricular tachyarrhythmias that are seen most commonly in acute myocardial infarction. Pharmacologic therapy, including the use of some of the newer antiarrhythmic agents, will be discussed, as will pacemaker ther apy of both bradyarrhythmias and tachyarrhythmias.



Drug Utilization Review In Skilled Nursing Facilities


Drug Utilization Review In Skilled Nursing Facilities
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Author : Hugh F. Kabat
language : en
Publisher:
Release Date : 1975

Drug Utilization Review In Skilled Nursing Facilities written by Hugh F. Kabat and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Chemotherapy categories.




Chemicals Identified In Human Biological Media


Chemicals Identified In Human Biological Media
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Author :
language : en
Publisher:
Release Date : 1981

Chemicals Identified In Human Biological Media written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Biochemistry categories.